| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the betaxolol-1592 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT9 | acyl-CoA thioesterase 9 |
| ACTN2 | actinin, alpha 2 |
| AHR | aryl hydrocarbon receptor |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARMC6 | armadillo repeat containing 6 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CD320 | CD320 molecule |
| CDCA3 | cell division cycle associated 3 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP85 | centrosomal protein 85kDa |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CNTNAP1 | contactin associated protein 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EFNB3 | ephrin-B3 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ELK1 | ELK1, member of ETS oncogene family |
| EVL | Enah/Vasp-like |
| FAM188A | family with sequence similarity 188, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FBXO9 | F-box protein 9 |
| FNBP1 | formin binding protein 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GML | glycosylphosphatidylinositol anchored molecule like |
| IRF4 | interferon regulatory factor 4 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLK13 | kallikrein-related peptidase 13 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LRRC15 | leucine rich repeat containing 15 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| METTL5 | methyltransferase like 5 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MOB1A | MOB kinase activator 1A |
| MTMR3 | myotubularin related protein 3 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYO1C | myosin IC |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit |
| NAAA | N-acylethanolamine acid amidase |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDRG2 | NDRG family member 2 |
| NMB | neuromedin B |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDCL | phosducin-like |
| PDS5A | PDS5 cohesin associated factor A |
| PER2 | period circadian clock 2 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLD2 | phospholipase D2 |
| PORCN | porcupine homolog (Drosophila) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTMA | prothymosin, alpha |
| RAB28 | RAB28, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RHOH | ras homolog family member H |
| RIOK3 | RIO kinase 3 |
| RPL7 | ribosomal protein L7 |
| SDC2 | syndecan 2 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SGSM3 | small G protein signaling modulator 3 |
| SHROOM2 | shroom family member 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
| SNX15 | sorting nexin 15 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPN | sialophorin |
| SRBD1 | S1 RNA binding domain 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| THRB | thyroid hormone receptor, beta |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZNF510 | zinc finger protein 510 |
| ZNF771 | zinc finger protein 771 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AACS | acetoacetyl-CoA synthetase |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACOT8 | acyl-CoA thioesterase 8 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APOBR | apolipoprotein B receptor |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMC7 | armadillo repeat containing 7 |
| ATG2A | autophagy related 2A |
| AURKB | aurora kinase B |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCDC47 | coiled-coil domain containing 47 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CDC34 | cell division cycle 34 |
| CDK5 | cyclin-dependent kinase 5 |
| CDKN2AIP | CDKN2A interacting protein |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFL1 | cofilin 1 (non-muscle) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CPNE1 | copine I |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DPP3 | dipeptidyl-peptidase 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EMC2 | ER membrane protein complex subunit 2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EXOC5 | exocyst complex component 5 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FTO | fat mass and obesity associated |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| ICAM3 | intercellular adhesion molecule 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JMJD4 | jumonji domain containing 4 |
| KIFC1 | kinesin family member C1 |
| LMAN2L | lectin, mannose-binding 2-like |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MLPH | melanophilin |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| NABP2 | nucleic acid binding protein 2 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUBP1 | nucleotide binding protein 1 |
| NUP93 | nucleoporin 93kDa |
| OAZ2 | ornithine decarboxylase antizyme 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PANX1 | pannexin 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PITRM1 | pitrilysin metallopeptidase 1 |
| PODNL1 | podocan-like 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| RAD9A | RAD9 homolog A (S. pombe) |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| RWDD2B | RWD domain containing 2B |
| SLC25A38 | solute carrier family 25, member 38 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A4RG | SLC2A4 regulator |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| TAC3 | tachykinin 3 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNRC6B | trinucleotide repeat containing 6B |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TXLNA | taxilin alpha |
| TXNDC15 | thioredoxin domain containing 15 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 |
| ZNF189 | zinc finger protein 189 |
