| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the betaxolol-3208 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BPY2 | basic charge, Y-linked, 2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC181 | coiled-coil domain containing 181 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CEP152 | centrosomal protein 152kDa |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CPA4 | carboxypeptidase A4 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DICER1 | dicer 1, ribonuclease type III |
| EDNRA | endothelin receptor type A |
| EML3 | echinoderm microtubule associated protein like 3 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EXPH5 | exophilin 5 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGF4 | fibroblast growth factor 4 |
| FKBP6 | FK506 binding protein 6, 36kDa |
| FMO5 | flavin containing monooxygenase 5 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GPR88 | G protein-coupled receptor 88 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GSTP1 | glutathione S-transferase pi 1 |
| HAVCR1 | hepatitis A virus cellular receptor 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HHAT | hedgehog acyltransferase |
| HIST1H1T | histone cluster 1, H1t |
| HOXA10 | homeobox A10 |
| HPN | hepsin |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL20RA | interleukin 20 receptor, alpha |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JAM3 | junctional adhesion molecule 3 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KLF13 | Kruppel-like factor 13 |
| KLHL22 | kelch-like family member 22 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| METTL7A | methyltransferase like 7A |
| MYOZ3 | myozenin 3 |
| MZF1 | myeloid zinc finger 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| OBSL1 | obscurin-like 1 |
| ONECUT2 | one cut homeobox 2 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLXNB1 | plexin B1 |
| PLXNB2 | plexin B2 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRTN3 | proteinase 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAB11B | RAB11B, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBFA | ribosome binding factor A (putative) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RETN | resistin |
| RGS14 | regulator of G-protein signaling 14 |
| RHBDL1 | rhomboid, veinlet-like 1 (Drosophila) |
| RUNX1 | runt-related transcription factor 1 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SNAI2 | snail family zinc finger 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNX13 | sorting nexin 13 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRR1B | small proline-rich protein 1B |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TENM1 | teneurin transmembrane protein 1 |
| TEX15 | testis expressed 15 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFB1 | transforming growth factor, beta 1 |
| TMEM242 | transmembrane protein 242 |
| TNC | tenascin C |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF41 | zinc finger protein 41 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BFSP1 | beaded filament structural protein 1, filensin |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCNO | cyclin O |
| CENPO | centromere protein O |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CNN2 | calponin 2 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CSTA | cystatin A (stefin A) |
| DBR1 | debranching RNA lariats 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| E2F8 | E2F transcription factor 8 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIRA | histone cell cycle regulator |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BC | histone cluster 1, H2bc |
| HSPA1L | heat shock 70kDa protein 1-like |
| IL17RA | interleukin 17 receptor A |
| IRF6 | interferon regulatory factor 6 |
| ITGA6 | integrin, alpha 6 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC257152 | uncharacterized LOC257152 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYZ | lysozyme |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANBA | mannosidase, beta A, lysosomal |
| METTL4 | methyltransferase like 4 |
| MICB | MHC class I polypeptide-related sequence B |
| MTMR6 | myotubularin related protein 6 |
| MVD | mevalonate (diphospho) decarboxylase |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NEK11 | NIMA-related kinase 11 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OTUD3 | OTU deubiquitinase 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PSKH1 | protein serine kinase H1 |
| RARS | arginyl-tRNA synthetase |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM42 | RNA binding motif protein 42 |
| RGS20 | regulator of G-protein signaling 20 |
| RIN2 | Ras and Rab interactor 2 |
| RNF121 | ring finger protein 121 |
| S100A4 | S100 calcium binding protein A4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SECTM1 | secreted and transmembrane 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TDRD1 | tudor domain containing 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMEM165 | transmembrane protein 165 |
| TMEM209 | transmembrane protein 209 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TPCN1 | two pore segment channel 1 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TSPYL2 | TSPY-like 2 |
| VEGFB | vascular endothelial growth factor B |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
| WASF2 | WAS protein family, member 2 |
| WDR82 | WD repeat domain 82 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF189 | zinc finger protein 189 |
| ZNF212 | zinc finger protein 212 |
| ZNF280D | zinc finger protein 280D |
| ZNF35 | zinc finger protein 35 |
| ZNF571 | zinc finger protein 571 |
| ZNF586 | zinc finger protein 586 |
| ZNF696 | zinc finger protein 696 |
| ZNF816 | zinc finger protein 816 |
