| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the betaxolol-4608 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACAN | aggrecan |
| ADRA2C | adrenoceptor alpha 2C |
| AGRP | agouti related neuropeptide |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| APOB | apolipoprotein B |
| BEX1 | brain expressed, X-linked 1 |
| BGN | biglycan |
| BRD7P3 | bromodomain containing 7 pseudogene 3 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CARD10 | caspase recruitment domain family, member 10 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK2 | cyclin-dependent kinase 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DKKL1 | dickkopf-like 1 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DLX2 | distal-less homeobox 2 |
| DSC1 | desmocollin 1 |
| DTNA | dystrobrevin, alpha |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPO | erythropoietin |
| EPYC | epiphycan |
| FAM63A | family with sequence similarity 63, member A |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HBB | hemoglobin, beta |
| HIST1H3F | histone cluster 1, H3f |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IHH | indian hedgehog |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIR2DS4 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 |
| KLHL22 | kelch-like family member 22 |
| KLK12 | kallikrein-related peptidase 12 |
| KLK3 | kallikrein-related peptidase 3 |
| LOXL3 | lysyl oxidase-like 3 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MLANA | melan-A |
| MTRF1L | mitochondrial translational release factor 1-like |
| MUC4 | mucin 4, cell surface associated |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| NPPA | natriuretic peptide A |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDE11A | phosphodiesterase 11A |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PML | promyelocytic leukemia |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRPH | peripherin |
| PRY | PTPN13-like, Y-linked |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| RET | ret proto-oncogene |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2D1A | SH2 domain containing 1A |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TAS2R8 | taste receptor, type 2, member 8 |
| THOC5 | THO complex 5 |
| TLE4 | transducin-like enhancer of split 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM40 | transmembrane protein 40 |
| TRD | T cell receptor delta locus |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TSHR | thyroid stimulating hormone receptor |
| TSKS | testis-specific serine kinase substrate |
| TSSK2 | testis-specific serine kinase 2 |
| UNC93A | unc-93 homolog A (C. elegans) |
| UPK2 | uroplakin 2 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF471 | zinc finger protein 471 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CBX7 | chromobox homolog 7 |
| CCDC106 | coiled-coil domain containing 106 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CISH | cytokine inducible SH2-containing protein |
| CLDND1 | claudin domain containing 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CORO1A | coronin, actin binding protein, 1A |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGF | epidermal growth factor |
| EN2 | engrailed homeobox 2 |
| ETNK2 | ethanolamine kinase 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FLCN | folliculin |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| GPR3 | G protein-coupled receptor 3 |
| GRAMD1B | GRAM domain containing 1B |
| H1F0 | H1 histone family, member 0 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1T | histone cluster 1, H1t |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0753 | KIAA0753 |
| KIAA1549L | KIAA1549-like |
| KIFC1 | kinesin family member C1 |
| KRT75 | keratin 75, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP7D1 | MAP7 domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MVP | major vault protein |
| NDP | Norrie disease (pseudoglioma) |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PALM | paralemmin |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PKN1 | protein kinase N1 |
| PLAC8 | placenta-specific 8 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RASA2 | RAS p21 protein activator 2 |
| REEP4 | receptor accessory protein 4 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRAGB | Ras-related GTP binding B |
| SIRT6 | sirtuin 6 |
| SLC12A9 | solute carrier family 12, member 9 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STK16 | serine/threonine kinase 16 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UNKL | unkempt family zinc finger-like |
| USP20 | ubiquitin specific peptidase 20 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF253 | zinc finger protein 253 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
