| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the betaxolol-5669 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM11 | ADAM metallopeptidase domain 11 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADRB1 | adrenoceptor beta 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPH | amphiphysin |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOL6 | apolipoprotein L, 6 |
| APOM | apolipoprotein M |
| ATP11A | ATPase, class VI, type 11A |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BTNL3 | butyrophilin-like 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CNPY4 | canopy FGF signaling regulator 4 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| EFNB3 | ephrin-B3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GLRA2 | glycine receptor, alpha 2 |
| GPR50 | G protein-coupled receptor 50 |
| GRAMD1C | GRAM domain containing 1C |
| GRM6 | glutamate receptor, metabotropic 6 |
| GYPC | glycophorin C (Gerbich blood group) |
| HBEGF | heparin-binding EGF-like growth factor |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4E | histone cluster 1, H4e |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IGL | immunoglobulin lambda locus |
| IL1R2 | interleukin 1 receptor, type II |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRS2 | insulin receptor substrate 2 |
| ITGB7 | integrin, beta 7 |
| KLF12 | Kruppel-like factor 12 |
| KRT83 | keratin 83, type II |
| LOXL3 | lysyl oxidase-like 3 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYZ | lysozyme |
| LYZL6 | lysozyme-like 6 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MUSK | muscle, skeletal, receptor tyrosine kinase |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEK1 | NIMA-related kinase 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NF1 | neurofibromin 1 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRSN2 | neurensin 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDPN | podoplanin |
| PEG3 | paternally expressed 3 |
| PMP2 | peripheral myelin protein 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RHCG | Rh family, C glycoprotein |
| RND1 | Rho family GTPase 1 |
| SALL1 | spalt-like transcription factor 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| STOML1 | stomatin (EPB72)-like 1 |
| SYT2 | synaptotagmin II |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM10 | tripartite motif containing 10 |
| TRIM3 | tripartite motif containing 3 |
| UPK3B | uroplakin 3B |
| VCAN | versican |
| ZNF154 | zinc finger protein 154 |
| ZNF197 | zinc finger protein 197 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADCY6 | adenylate cyclase 6 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAX | BCL2-associated X protein |
| BBC3 | BCL2 binding component 3 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC186 | coiled-coil domain containing 186 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CTAGE9 | CTAGE family, member 9 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EFNA3 | ephrin-A3 |
| FAAH | fatty acid amide hydrolase |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRK | fyn-related Src family tyrosine kinase |
| FUZ | fuzzy planar cell polarity protein |
| GLI3 | GLI family zinc finger 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFT140 | intraflagellar transport 140 |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0895 | KIAA0895 |
| KIFC1 | kinesin family member C1 |
| LMNB1 | lamin B1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| NKX3-2 | NK3 homeobox 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OCA2 | oculocutaneous albinism II |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PC | pyruvate carboxylase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMCH | pro-melanin-concentrating hormone |
| PODNL1 | podocan-like 1 |
| PODXL2 | podocalyxin-like 2 |
| PRPH | peripherin |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNX10 | sorting nexin 10 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STIM1 | stromal interaction molecule 1 |
| STK4 | serine/threonine kinase 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBR1 | T-box, brain, 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM180 | transmembrane protein 180 |
| TRAIP | TRAF interacting protein |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| UBQLN4 | ubiquilin 4 |
| VEGFC | vascular endothelial growth factor C |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VIM | vimentin |
| WWC2 | WW and C2 domain containing 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF136 | zinc finger protein 136 |
| ZNF211 | zinc finger protein 211 |
| ZNF286A | zinc finger protein 286A |
| ZNF571 | zinc finger protein 571 |
| ZNF606 | zinc finger protein 606 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
