betazole-1812 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the betazole-1812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKTIP AKT interacting protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APH1A APH1A gamma secretase subunit
APOL6 apolipoprotein L, 6
ATAD5 ATPase family, AAA domain containing 5
B9D1 B9 protein domain 1
BAX BCL2-associated X protein
BCL9 B-cell CLL/lymphoma 9
C11ORF30 chromosome 11 open reading frame 30
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN10 calpain 10
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK17 cyclin-dependent kinase 17
CDK3 cyclin-dependent kinase 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTSZ cathepsin Z
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXCL3 chemokine (C-X-C motif) ligand 3
CYHR1 cysteine/histidine-rich 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLL3 delta-like 3 (Drosophila)
DNPEP aspartyl aminopeptidase
E2F4 E2F transcription factor 4, p107/p130-binding
EGR1 early growth response 1
EML2 echinoderm microtubule associated protein like 2
EML3 echinoderm microtubule associated protein like 3
FAM149B1 family with sequence similarity 149, member B1
FGD6 FYVE, RhoGEF and PH domain containing 6
FNDC4 fibronectin type III domain containing 4
FSCN1 fascin actin-bundling protein 1
H1F0 H1 histone family, member 0
HHEX hematopoietically expressed homeobox
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP5 insulin-like growth factor binding protein 5
ING1 inhibitor of growth family, member 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA10 integrin, alpha 10
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KHSRP KH-type splicing regulatory protein
KIAA0485 uncharacterized LOC57235
LMNB1 lamin B1
LYPD3 LY6/PLAUR domain containing 3
MDM1 Mdm1 nuclear protein homolog (mouse)
MMP3 matrix metallopeptidase 3
MPDZ multiple PDZ domain protein
MRPS11 mitochondrial ribosomal protein S11
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NGF nerve growth factor (beta polypeptide)
NID2 nidogen 2 (osteonidogen)
NOV nephroblastoma overexpressed
ORAI2 ORAI calcium release-activated calcium modulator 2
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
QKI QKI, KH domain containing, RNA binding
RAB11B RAB11B, member RAS oncogene family
RARS arginyl-tRNA synthetase
RNF126P1 ring finger protein 126 pseudogene 1
SCAMP5 secretory carrier membrane protein 5
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS6 suppressor of cytokine signaling 6
SRRM2 serine/arginine repetitive matrix 2
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUSD6 sushi domain containing 6
TADA2A transcriptional adaptor 2A
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAOK1 TAO kinase 1
TBC1D30 TBC1 domain family, member 30
TBX2 T-box 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPD52L1 tumor protein D52-like 1
USP27X ubiquitin specific peptidase 27, X-linked
UTRN utrophin
ZFX zinc finger protein, X-linked
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF239 zinc finger protein 239
ZNF280D zinc finger protein 280D
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
ACBD4 acyl-CoA binding domain containing 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMPD2 adenosine monophosphate deaminase 2
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL2 ADP-ribosylation factor-like 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BBS7 Bardet-Biedl syndrome 7
C10ORF2 chromosome 10 open reading frame 2
C16ORF59 chromosome 16 open reading frame 59
C1ORF112 chromosome 1 open reading frame 112
C1R complement component 1, r subcomponent
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
CAPN15 calpain 15
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNJL cyclin J-like
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CGREF1 cell growth regulator with EF-hand domain 1
CINP cyclin-dependent kinase 2 interacting protein
CLCF1 cardiotrophin-like cytokine factor 1
CLIC3 chloride intracellular channel 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRIP2 cysteine-rich protein 2
CUEDC1 CUE domain containing 1
DCLRE1B DNA cross-link repair 1B
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
E2F1 E2F transcription factor 1
EAF2 ELL associated factor 2
EDN1 endothelin 1
FER fer (fps/fes related) tyrosine kinase
FLJ22184
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUZ fuzzy planar cell polarity protein
GALK1 galactokinase 1
GLI3 GLI family zinc finger 3
GPR176 G protein-coupled receptor 176
GRAMD1C GRAM domain containing 1C
GSDMD gasdermin D
GTPBP6 GTP binding protein 6 (putative)
HAUS6 HAUS augmin-like complex, subunit 6
HOXC4 homeobox C4
HYI hydroxypyruvate isomerase (putative)
IGFLR1 IGF-like family receptor 1
IL17RA interleukin 17 receptor A
IL32 interleukin 32
JUNB jun B proto-oncogene
KIAA0513 KIAA0513
KIFC3 kinesin family member C3
KRT15 keratin 15, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRP5 low density lipoprotein receptor-related protein 5
METTL2B methyltransferase like 2B
MGC12488
MPST mercaptopyruvate sulfurtransferase
MX1 MX dynamin-like GTPase 1
MYL5 myosin, light chain 5, regulatory
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLD2 phospholipase D2
PMM1 phosphomannomutase 1
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF25 ring finger protein 25
RNF31 ring finger protein 31
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SIX1 SIX homeobox 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAP29 synaptosomal-associated protein, 29kDa
SND1-IT1 SND1 intronic transcript 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3 stromal antigen 3
SYT17 synaptotagmin XVII
TBC1D12 TBC1 domain family, member 12
TINAGL1 tubulointerstitial nephritis antigen-like 1
TKFC triokinase/FMN cyclase
TMSB15A thymosin beta 15a
TNNI3 troponin I type 3 (cardiac)
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN12 tetraspanin 12
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UNC119 unc-119 homolog (C. elegans)
WDR18 WD repeat domain 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB3 zinc finger and BTB domain containing 3
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene
ZNF778 zinc finger protein 778