betazole-1854 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the betazole-1854 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRL1 adhesion G protein-coupled receptor L1
ATP11A ATPase, class VI, type 11A
AURKA aurora kinase A
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C1ORF56 chromosome 1 open reading frame 56
CCL22 chemokine (C-C motif) ligand 22
CCS copper chaperone for superoxide dismutase
CD38 CD38 molecule
CD86 CD86 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CENPA centromere protein A
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC4E C-type lectin domain family 4, member E
CLIP2 CAP-GLY domain containing linker protein 2
CNOT4 CCR4-NOT transcription complex, subunit 4
CRELD1 cysteine-rich with EGF-like domains 1
CREM cAMP responsive element modulator
CRYL1 crystallin, lambda 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNS cystinosin, lysosomal cystine transporter
CTSB cathepsin B
CYTH1 cytohesin 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGAT1 diacylglycerol O-acyltransferase 1
DUSP1 dual specificity phosphatase 1
E2F4 E2F transcription factor 4, p107/p130-binding
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EPHB2 EPH receptor B2
EPHB6 EPH receptor B6
EPS8L1 EPS8-like 1
ERCC6 excision repair cross-complementation group 6
ERCC6L excision repair cross-complementation group 6-like
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM13A family with sequence similarity 13, member A
FAM149B1 family with sequence similarity 149, member B1
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLP1R glucagon-like peptide 1 receptor
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTDC1 glycosyltransferase-like domain containing 1
HLA-DRA major histocompatibility complex, class II, DR alpha
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFFO1 intermediate filament family orphan 1
IGFLR1 IGF-like family receptor 1
IL1B interleukin 1, beta
INF2 inverted formin, FH2 and WH2 domain containing
ING4 inhibitor of growth family, member 4
IQSEC1 IQ motif and Sec7 domain 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
KYNU kynureninase
MAP2K7 mitogen-activated protein kinase kinase 7
MAP7 microtubule-associated protein 7
MIIP migration and invasion inhibitory protein
MKL2 MKL/myocardin-like 2
MPZ myelin protein zero
MST1 macrophage stimulating 1
MTUS1 microtubule associated tumor suppressor 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYL10 myosin, light chain 10, regulatory
NCOA2 nuclear receptor coactivator 2
NES nestin
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRP1 neuropilin 1
PORCN porcupine homolog (Drosophila)
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP1R7 protein phosphatase 1, regulatory subunit 7
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM5 RNA binding motif protein 5
RRBP1 ribosome binding protein 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SH2D2A SH2 domain containing 2A
SIDT2 SID1 transmembrane family, member 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC12A8 solute carrier family 12, member 8
SLC31A2 solute carrier family 31 (copper transporter), member 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
STS steroid sulfatase (microsomal), isozyme S
TBC1D2 TBC1 domain family, member 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TMCC1 transmembrane and coiled-coil domain family 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRADD TNFRSF1A-associated via death domain
TRD T cell receptor delta locus
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ANKRD55 ankyrin repeat domain 55
ANXA3 annexin A3
APOL6 apolipoprotein L, 6
ARHGAP10 Rho GTPase activating protein 10
BBS7 Bardet-Biedl syndrome 7
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BYSL bystin-like
C12ORF29 chromosome 12 open reading frame 29
C2CD2 C2 calcium-dependent domain containing 2
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
CA2 carbonic anhydrase II
CBS cystathionine-beta-synthase
CCDC86 coiled-coil domain containing 86
CEP72 centrosomal protein 72kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CTSG cathepsin G
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOSC5 exosome component 5
FADS2 fatty acid desaturase 2
FAM13B family with sequence similarity 13, member B
FAM216A family with sequence similarity 216, member A
FAM86B1 family with sequence similarity 86, member B1
FBXL15 F-box and leucine-rich repeat protein 15
GALT galactose-1-phosphate uridylyltransferase
GPHN gephyrin
GPR63 G protein-coupled receptor 63
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HEATR3 HEAT repeat containing 3
HSPA4L heat shock 70kDa protein 4-like
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT57 intraflagellar transport 57
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ISOC2 isochorismatase domain containing 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LZTR1 leucine-zipper-like transcription regulator 1
METTL8 methyltransferase like 8
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL12 mitochondrial ribosomal protein L12
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NARFL nuclear prelamin A recognition factor-like
NAT10 N-acetyltransferase 10 (GCN5-related)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NKRF NFKB repressing factor
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL6 nucleolar protein 6 (RNA-associated)
PFAS phosphoribosylformylglycinamidine synthase
PGPEP1 pyroglutamyl-peptidase I
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLXND1 plexin D1
PNMA1 paraneoplastic Ma antigen 1
PRR7 proline rich 7 (synaptic)
PSAT1 phosphoserine aminotransferase 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PUS7 pseudouridylate synthase 7 (putative)
RBM28 RNA binding motif protein 28
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNH1 ribonuclease/angiogenin inhibitor 1
RPIA ribose 5-phosphate isomerase A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RSAD1 radical S-adenosyl methionine domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
SCRIB scribbled planar cell polarity protein
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEH1L SEH1-like (S. cerevisiae)
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNX15 sorting nexin 15
SRD5A3 steroid 5 alpha-reductase 3
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TEC tec protein tyrosine kinase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM177 transmembrane protein 177
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTF2 transcription termination factor, RNA polymerase II
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBFD1 ubiquitin family domain containing 1
USP20 ubiquitin specific peptidase 20
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43
ZNF536 zinc finger protein 536
ZNF671 zinc finger protein 671