betazole-5445 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the betazole-5445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADAM12 ADAM metallopeptidase domain 12
ADD2 adducin 2 (beta)
ADGRB3 adhesion G protein-coupled receptor B3
AFF3 AF4/FMR2 family, member 3
AIM1L absent in melanoma 1-like
ALB albumin
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APAF1 apoptotic peptidase activating factor 1
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP1 bone morphogenetic protein 1
C14ORF1 chromosome 14 open reading frame 1
C1QL1 complement component 1, q subcomponent-like 1
CCDC132 coiled-coil domain containing 132
CCL22 chemokine (C-C motif) ligand 22
CD47 CD47 molecule
CD86 CD86 molecule
CDHR2 cadherin-related family member 2
CHM choroideremia (Rab escort protein 1)
CLEC4E C-type lectin domain family 4, member E
CLSTN3 calsyntenin 3
CLTA clathrin, light chain A
CNGA1 cyclic nucleotide gated channel alpha 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CNTNAP1 contactin associated protein 1
COL19A1 collagen, type XIX, alpha 1
DENND6B DENN/MADD domain containing 6B
DNASE2B deoxyribonuclease II beta
DSC3 desmocollin 3
ETV6 ets variant 6
EXOSC2 exosome component 2
FZD1 frizzled class receptor 1
GK3P glycerol kinase 3 pseudogene
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR137 G protein-coupled receptor 137
GTDC1 glycosyltransferase-like domain containing 1
HDAC7 histone deacetylase 7
HIPK3 homeodomain interacting protein kinase 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA1 homeobox A1
HOXA4 homeobox A4
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL1RN interleukin 1 receptor antagonist
IL9R interleukin 9 receptor
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KDM8 lysine (K)-specific demethylase 8
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KREMEN2 kringle containing transmembrane protein 2
LAMP1 lysosomal-associated membrane protein 1
LCT lactase
LMF2 lipase maturation factor 2
MAP4 microtubule-associated protein 4
MATN1 matrilin 1, cartilage matrix protein
MCTP2 multiple C2 domains, transmembrane 2
METTL5 methyltransferase like 5
MSR1 macrophage scavenger receptor 1
MTL5 metallothionein-like 5, testis-specific (tesmin)
MUC3B mucin 3B, cell surface associated
NCOR2 nuclear receptor corepressor 2
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NUP188 nucleoporin 188kDa
OASL 2'-5'-oligoadenylate synthetase-like
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCM1 pericentriolar material 1
PEX3 peroxisomal biogenesis factor 3
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PVR poliovirus receptor
RAB3B RAB3B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RECQL5 RecQ protein-like 5
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS20 regulator of G-protein signaling 20
S100A1 S100 calcium binding protein A1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFRP4 secreted frizzled-related protein 4
SLMO1 slowmo homolog 1 (Drosophila)
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SRSF5 serine/arginine-rich splicing factor 5
SSTR5 somatostatin receptor 5
SV2C synaptic vesicle glycoprotein 2C
TBRG4 transforming growth factor beta regulator 4
TBX21 T-box 21
TP53I11 tumor protein p53 inducible protein 11
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WSB1 WD repeat and SOCS box containing 1
ZBTB18 zinc finger and BTB domain containing 18
ZHX3 zinc fingers and homeoboxes 3
ZNF44 zinc finger protein 44
ZNF609 zinc finger protein 609
ZNF750 zinc finger protein 750
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACBD4 acyl-CoA binding domain containing 4
ACTL8 actin-like 8
AHDC1 AT hook, DNA binding motif, containing 1
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANXA2P3 annexin A2 pseudogene 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF88 chromosome 10 open reading frame 88
C11ORF80 chromosome 11 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C7ORF43 chromosome 7 open reading frame 43
C8ORF60 chromosome 8 open reading frame 60
CAPN5 calpain 5
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A5 collagen, type IV, alpha 5
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
DBF4B DBF4 zinc finger B
DGAT1 diacylglycerol O-acyltransferase 1
DNAL4 dynein, axonemal, light chain 4
DPY19L1P1 DPY19L1 pseudogene 1
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO4 F-box protein 4
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GLRA1 glycine receptor, alpha 1
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H3E histone cluster 1, H3e
HYI hydroxypyruvate isomerase (putative)
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
ITPKC inositol-trisphosphate 3-kinase C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0754 KIAA0754
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LOC257152 uncharacterized LOC257152
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3A mucin 3A, cell surface associated
N4BP3 NEDD4 binding protein 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOD1 nucleotide-binding oligomerization domain containing 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA9 protocadherin alpha 9
PLCG1 phospholipase C, gamma 1
PODNL1 podocan-like 1
RAB30 RAB30, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RUSC2 RUN and SH3 domain containing 2
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP7 SUMO1/sentrin specific peptidase 7
SETD1A SET domain containing 1A
SKI SKI proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLN sarcolipin
SOAT2 sterol O-acyltransferase 2
SPON2 spondin 2, extracellular matrix protein
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPP1 uridine phosphorylase 1
VASH2 vasohibin 2
WDR62 WD repeat domain 62
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF446 zinc finger protein 446