| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the betazole-5445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADD2 | adducin 2 (beta) |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| AFF3 | AF4/FMR2 family, member 3 |
| AIM1L | absent in melanoma 1-like |
| ALB | albumin |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BMP1 | bone morphogenetic protein 1 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD47 | CD47 molecule |
| CD86 | CD86 molecule |
| CDHR2 | cadherin-related family member 2 |
| CHM | choroideremia (Rab escort protein 1) |
| CLEC4E | C-type lectin domain family 4, member E |
| CLSTN3 | calsyntenin 3 |
| CLTA | clathrin, light chain A |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| CNTNAP1 | contactin associated protein 1 |
| COL19A1 | collagen, type XIX, alpha 1 |
| DENND6B | DENN/MADD domain containing 6B |
| DNASE2B | deoxyribonuclease II beta |
| DSC3 | desmocollin 3 |
| ETV6 | ets variant 6 |
| EXOSC2 | exosome component 2 |
| FZD1 | frizzled class receptor 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR137 | G protein-coupled receptor 137 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HDAC7 | histone deacetylase 7 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL1RN | interleukin 1 receptor antagonist |
| IL9R | interleukin 9 receptor |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LCT | lactase |
| LMF2 | lipase maturation factor 2 |
| MAP4 | microtubule-associated protein 4 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| METTL5 | methyltransferase like 5 |
| MSR1 | macrophage scavenger receptor 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MUC3B | mucin 3B, cell surface associated |
| NCOR2 | nuclear receptor corepressor 2 |
| NF1 | neurofibromin 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NUP188 | nucleoporin 188kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCM1 | pericentriolar material 1 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PVR | poliovirus receptor |
| RAB3B | RAB3B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RECQL5 | RecQ protein-like 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS20 | regulator of G-protein signaling 20 |
| S100A1 | S100 calcium binding protein A1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SFRP4 | secreted frizzled-related protein 4 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SSTR5 | somatostatin receptor 5 |
| SV2C | synaptic vesicle glycoprotein 2C |
| TBRG4 | transforming growth factor beta regulator 4 |
| TBX21 | T-box 21 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF44 | zinc finger protein 44 |
| ZNF609 | zinc finger protein 609 |
| ZNF750 | zinc finger protein 750 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AXIN1 | axin 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPN5 | calpain 5 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CRY2 | cryptochrome circadian clock 2 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DBF4B | DBF4 zinc finger B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO4 | F-box protein 4 |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GLRA1 | glycine receptor, alpha 1 |
| GPR27 | G protein-coupled receptor 27 |
| GPR87 | G protein-coupled receptor 87 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3E | histone cluster 1, H3e |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0754 | KIAA0754 |
| LHX6 | LIM homeobox 6 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC257152 | uncharacterized LOC257152 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MUC3A | mucin 3A, cell surface associated |
| N4BP3 | NEDD4 binding protein 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCDHA9 | protocadherin alpha 9 |
| PLCG1 | phospholipase C, gamma 1 |
| PODNL1 | podocan-like 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF122 | ring finger protein 122 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SETD1A | SET domain containing 1A |
| SKI | SKI proto-oncogene |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLN | sarcolipin |
| SOAT2 | sterol O-acyltransferase 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STEAP4 | STEAP family member 4 |
| TOM1 | target of myb1 (chicken) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPP1 | uridine phosphorylase 1 |
| VASH2 | vasohibin 2 |
| WDR62 | WD repeat domain 62 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF446 | zinc finger protein 446 |