| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the betonicine-2207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP13A2 | ATPase type 13A2 |
| BIN1 | bridging integrator 1 |
| BNC1 | basonuclin 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAV2 | caveolin 2 |
| CD180 | CD180 molecule |
| CD84 | CD84 molecule |
| CLEC4E | C-type lectin domain family 4, member E |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| DSCAM | Down syndrome cell adhesion molecule |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EMP1 | epithelial membrane protein 1 |
| ENG | endoglin |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPS8L2 | EPS8-like 2 |
| FAM13A | family with sequence similarity 13, member A |
| FOXD1 | forkhead box D1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPX2 | glutathione peroxidase 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HOXA1 | homeobox A1 |
| HOXA10 | homeobox A10 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF3A | kinesin family member 3A |
| KLC2 | kinesin light chain 2 |
| KRT86 | keratin 86, type II |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED16 | mediator complex subunit 16 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUP50 | nucleoporin 50kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PERP | PERP, TP53 apoptosis effector |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEC | plectin |
| PLXNA3 | plexin A3 |
| POU6F1 | POU class 6 homeobox 1 |
| PRPF18 | pre-mRNA processing factor 18 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| REC8 | REC8 meiotic recombination protein |
| RGS12 | regulator of G-protein signaling 12 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| STAB2 | stabilin 2 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STOM | stomatin |
| SV2B | synaptic vesicle glycoprotein 2B |
| SYN2 | synapsin II |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCF4 | transcription factor 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEF | thyrotrophic embryonic factor |
| THAP10 | THAP domain containing 10 |
| THTPA | thiamine triphosphatase |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIM58 | tripartite motif containing 58 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TWF1 | twinfilin actin binding protein 1 |
| UPB1 | ureidopropionase, beta |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| USP53 | ubiquitin specific peptidase 53 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WNT2 | wingless-type MMTV integration site family member 2 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOBR | apolipoprotein B receptor |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BNC2 | basonuclin 2 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA11 | carbonic anhydrase XI |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC85C | coiled-coil domain containing 85C |
| CD70 | CD70 molecule |
| CEL | carboxyl ester lipase |
| CEP170B | centrosomal protein 170B |
| CES3 | carboxylesterase 3 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CORT | cortistatin |
| DDN | dendrin |
| DEPDC5 | DEP domain containing 5 |
| DOC2A | double C2-like domains, alpha |
| DUSP8 | dual specificity phosphatase 8 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| EPHB6 | EPH receptor B6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM102A | family with sequence similarity 102, member A |
| FGL1 | fibrinogen-like 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTA4 | glutathione S-transferase alpha 4 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC8 | homeobox C8 |
| IFT140 | intraflagellar transport 140 |
| IL22 | interleukin 22 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLK5 | kallikrein-related peptidase 5 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LINS | lines homolog (Drosophila) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MICALL2 | MICAL-like 2 |
| MXD3 | MAX dimerization protein 3 |
| NKX3-2 | NK3 homeobox 2 |
| NME8 | NME/NM23 family member 8 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PER3 | period circadian clock 3 |
| PLP1 | proteolipid protein 1 |
| POLL | polymerase (DNA directed), lambda |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAF2 | PRA1 domain family, member 2 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF121 | ring finger protein 121 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI1 | snail family zinc finger 1 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STAP1 | signal transducing adaptor family member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAS2R4 | taste receptor, type 2, member 4 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XAB2 | XPA binding protein 2 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF324 | zinc finger protein 324 |
