| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the betonicine-3745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADRA1D | adrenoceptor alpha 1D |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| ATG10 | autophagy related 10 |
| BBC3 | BCL2 binding component 3 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD177 | CD177 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC2B | C-type lectin domain family 2, member B |
| COL1A1 | collagen, type I, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTSZ | cathepsin Z |
| CYBA | cytochrome b-245, alpha polypeptide |
| DESI2 | desumoylating isopeptidase 2 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DIO2 | deiodinase, iodothyronine, type II |
| DKFZP434C153 | DKFZP434C153 protein |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGR1 | early growth response 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FGF22 | fibroblast growth factor 22 |
| FLJ11292 | |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD4A | FERM domain containing 4A |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GAP43 | growth associated protein 43 |
| GFER | growth factor, augmenter of liver regeneration |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HABP4 | hyaluronan binding protein 4 |
| HSF1 | heat shock transcription factor 1 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL36G | interleukin 36, gamma |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LOC100294391 | uncharacterized LOC100294391 |
| LY9 | lymphocyte antigen 9 |
| MEF2D | myocyte enhancer factor 2D |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYL10 | myosin, light chain 10, regulatory |
| NCOR2 | nuclear receptor corepressor 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| ONECUT2 | one cut homeobox 2 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PHF20 | PHD finger protein 20 |
| PIGR | polymeric immunoglobulin receptor |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLK3 | polo-like kinase 3 |
| PQLC2 | PQ loop repeat containing 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRM1 | protamine 1 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVR | poliovirus receptor |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RGS4 | regulator of G-protein signaling 4 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| RPL10 | ribosomal protein L10 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SFRP1 | secreted frizzled-related protein 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| STAB2 | stabilin 2 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TBX1 | T-box 1 |
| TBX6 | T-box 6 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TLK1 | tousled-like kinase 1 |
| TMEM259 | transmembrane protein 259 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSPAN32 | tetraspanin 32 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF140 | zinc finger protein 140 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARSB | arylsulfatase B |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C1R | complement component 1, r subcomponent |
| C3 | complement component 3 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDH19 | cadherin 19, type 2 |
| CEP97 | centrosomal protein 97kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLSTN3 | calsyntenin 3 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COBL | cordon-bleu WH2 repeat protein |
| CRY2 | cryptochrome circadian clock 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNM3 | dynamin 3 |
| DOK5 | docking protein 5 |
| DYM | dymeclin |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGF | epidermal growth factor |
| FAM120C | family with sequence similarity 120C |
| FAM204A | family with sequence similarity 204, member A |
| FAM63A | family with sequence similarity 63, member A |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLB1L | galactosidase, beta 1-like |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HIST1H1D | histone cluster 1, H1d |
| HOXA4 | homeobox A4 |
| HOXA7 | homeobox A7 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT22 | intraflagellar transport 22 |
| IL22 | interleukin 22 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT37 | keratin 37, type I |
| KRT86 | keratin 86, type II |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEA3 | melanoma antigen family A3 |
| MCMBP | minichromosome maintenance complex binding protein |
| MDM4 | MDM4, p53 regulator |
| METTL16 | methyltransferase like 16 |
| MLYCD | malonyl-CoA decarboxylase |
| MYOZ3 | myozenin 3 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA9 | protocadherin alpha 9 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRAMEF10 | PRAME family member 10 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB30 | RAB30, member RAS oncogene family |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RGCC | regulator of cell cycle |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPANXC | SPANX family, member C |
| SPEG | SPEG complex locus |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNGR3 | synaptogyrin 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIGD6 | tigger transposable element derived 6 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TRABD | TraB domain containing |
| UBOX5 | U-box domain containing 5 |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF442 | zinc finger protein 442 |
| ZNF516 | zinc finger protein 516 |
| ZNF573 | zinc finger protein 573 |
| ZNF749 | zinc finger protein 749 |
