| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the betonicine-4301 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTSL4 | ADAMTS-like 4 |
| AFF1 | AF4/FMR2 family, member 1 |
| AQP4 | aquaporin 4 |
| AQP6 | aquaporin 6, kidney specific |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| AURKA | aurora kinase A |
| AVPR1A | arginine vasopressin receptor 1A |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTBP2 | C-terminal binding protein 2 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYTH3 | cytohesin 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK4 | docking protein 4 |
| DST | dystonin |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GK | glycerol kinase |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AB | histone cluster 1, H2ab |
| HRG | histidine-rich glycoprotein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGHM | immunoglobulin heavy constant mu |
| IL2RA | interleukin 2 receptor, alpha |
| IL6ST | interleukin 6 signal transducer |
| IRF4 | interferon regulatory factor 4 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIFC3 | kinesin family member C3 |
| KLHL18 | kelch-like family member 18 |
| LAT2 | linker for activation of T cells family, member 2 |
| LATS1 | large tumor suppressor kinase 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MOS | v-mos Moloney murine sarcoma viral oncogene homolog |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCLN | nicalin |
| NUP54 | nucleoporin 54kDa |
| ONECUT2 | one cut homeobox 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PCM1 | pericentriolar material 1 |
| PER2 | period circadian clock 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POU2F3 | POU class 2 homeobox 3 |
| POU6F1 | POU class 6 homeobox 1 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PTCH2 | patched 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB14 | RAB14, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| REEP2 | receptor accessory protein 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF2 | ring finger protein 2 |
| RUNDC3A | RUN domain containing 3A |
| SCARB1 | scavenger receptor class B, member 1 |
| SCN3B | sodium channel, voltage gated, type III beta subunit |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SUGP1 | SURP and G patch domain containing 1 |
| SZRD1 | SUZ RNA binding domain containing 1 |
| T | T, brachyury homolog (mouse) |
| TADA2A | transcriptional adaptor 2A |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TIPRL | TOR signaling pathway regulator |
| TMPO | thymopoietin |
| TROVE2 | TROVE domain family, member 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TTC39A | tetratricopeptide repeat domain 39A |
| WTAP | Wilms tumor 1 associated protein |
| ZFPL1 | zinc finger protein-like 1 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF280B | zinc finger protein 280B |
| ZNF749 | zinc finger protein 749 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANXA10 | annexin A10 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARRB2 | arrestin, beta 2 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| CAPN15 | calpain 15 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC7 | coiled-coil domain containing 7 |
| CD82 | CD82 molecule |
| CEP41 | centrosomal protein 41kDa |
| CERS4 | ceramide synthase 4 |
| CHRDL1 | chordin-like 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| CPNE7 | copine VII |
| DEAF1 | DEAF1 transcription factor |
| DOC2A | double C2-like domains, alpha |
| EFNB1 | ephrin-B1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EHD3 | EH-domain containing 3 |
| ETV7 | ets variant 7 |
| FAM110B | family with sequence similarity 110, member B |
| FBXO2 | F-box protein 2 |
| FMO4 | flavin containing monooxygenase 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPR22 | G protein-coupled receptor 22 |
| GRM6 | glutamate receptor, metabotropic 6 |
| H1F0 | H1 histone family, member 0 |
| HIST1H2BB | histone cluster 1, H2bb |
| HLX | H2.0-like homeobox |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA7 | homeobox A7 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HYI | hydroxypyruvate isomerase (putative) |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL2RG | interleukin 2 receptor, gamma |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KIAA0319L | KIAA0319-like |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL26 | kelch-like family member 26 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MST1 | macrophage stimulating 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYL9 | myosin, light chain 9, regulatory |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGP | phosphoglycolate phosphatase |
| PICK1 | protein interacting with PRKCA 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLXNB3 | plexin B3 |
| PMPCA | peptidase (mitochondrial processing) alpha |
| POM121 | POM121 transmembrane nucleoporin |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB5B | RAB5B, member RAS oncogene family |
| RBM19 | RNA binding motif protein 19 |
| RNF122 | ring finger protein 122 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RWDD2A | RWD domain containing 2A |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSTR4 | somatostatin receptor 4 |
| TAGLN | transgelin |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLN1 | talin 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN32 | tetraspanin 32 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZIC3 | Zic family member 3 |
| ZNF711 | zinc finger protein 711 |
