| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the betonicine-6063 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADCY9 | adenylate cyclase 9 |
| APOA1 | apolipoprotein A-I |
| AQP7 | aquaporin 7 |
| ATN1 | atrophin 1 |
| BGN | biglycan |
| BIN1 | bridging integrator 1 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CDHR2 | cadherin-related family member 2 |
| CHI3L2 | chitinase 3-like 2 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| COMP | cartilage oligomeric matrix protein |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CST4 | cystatin S |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCC | DCC netrin 1 receptor |
| DUSP9 | dual specificity phosphatase 9 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FAM106A | family with sequence similarity 106, member A |
| FGF6 | fibroblast growth factor 6 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FYB | FYN binding protein |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAS7 | growth arrest-specific 7 |
| GP5 | glycoprotein V (platelet) |
| GPATCH4 | G patch domain containing 4 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HDAC7 | histone deacetylase 7 |
| HHAT | hedgehog acyltransferase |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HNMT | histamine N-methyltransferase |
| HOXB3 | homeobox B3 |
| HR | hair growth associated |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR7P1 | 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 |
| IAPP | islet amyloid polypeptide |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL16 | interleukin 16 |
| ITGB7 | integrin, beta 7 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIF1C | kinesin family member 1C |
| KRT83 | keratin 83, type II |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAOA | monoamine oxidase A |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYOZ1 | myozenin 1 |
| NAG18 | NAG18 mRNA |
| OBSL1 | obscurin-like 1 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PROX1 | prospero homeobox 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RBMXL2 | RNA binding motif protein, X-linked-like 2 |
| RELN | reelin |
| RFPL3 | ret finger protein-like 3 |
| RGS14 | regulator of G-protein signaling 14 |
| RGS9 | regulator of G-protein signaling 9 |
| RTN2 | reticulon 2 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SH2D3A | SH2 domain containing 3A |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SP100 | SP100 nuclear antigen |
| SPATA6 | spermatogenesis associated 6 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TCF3 | transcription factor 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TPMT | thiopurine S-methyltransferase |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTL8 | actin-like 8 |
| ADM | adrenomedullin |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC6 | coiled-coil domain containing 6 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRY2 | cryptochrome circadian clock 2 |
| CRYGC | crystallin, gamma C |
| CTSF | cathepsin F |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBR1 | debranching RNA lariats 1 |
| DEAF1 | DEAF1 transcription factor |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSE | dermatan sulfate epimerase |
| EFNA3 | ephrin-A3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FRK | fyn-related Src family tyrosine kinase |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GID4 | GID complex subunit 4 |
| GPR21 | G protein-coupled receptor 21 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HDAC11 | histone deacetylase 11 |
| HIST1H4D | histone cluster 1, H4d |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXB2 | homeobox B2 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIF16B | kinesin family member 16B |
| LMNB1 | lamin B1 |
| LRRC61 | leucine rich repeat containing 61 |
| MALL | mal, T-cell differentiation protein-like |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MYL5 | myosin, light chain 5, regulatory |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PLA2G10 | phospholipase A2, group X |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RRAGB | Ras-related GTP binding B |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SH2D4A | SH2 domain containing 4A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPAG4 | sperm associated antigen 4 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBX19 | T-box 19 |
| TESC | tescalcin |
| THBS3 | thrombospondin 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TPTE | transmembrane phosphatase with tensin homology |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTBK2 | tau tubulin kinase 2 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| USP18 | ubiquitin specific peptidase 18 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR33 | WD repeat domain 33 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF143 | zinc finger protein 143 |
| ZNF273 | zinc finger protein 273 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF350 | zinc finger protein 350 |
| ZNF510 | zinc finger protein 510 |
| ZNF532 | zinc finger protein 532 |
| ZNF573 | zinc finger protein 573 |
