betulin-2952 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the betulin-2952 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADGRL3 adhesion G protein-coupled receptor L3
AKAP8L A kinase (PRKA) anchor protein 8-like
APLP2 amyloid beta (A4) precursor-like protein 2
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL2L1 BCL2-like 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CBX6 chromobox homolog 6
CCL4 chemokine (C-C motif) ligand 4
CCP110 centriolar coiled coil protein 110kDa
CDC25C cell division cycle 25C
CLEC11A C-type lectin domain family 11, member A
CSF3R colony stimulating factor 3 receptor (granulocyte)
CUX1 cut-like homeobox 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBT dihydrolipoamide branched chain transacylase E2
DEPDC1 DEP domain containing 1
DEPDC5 DEP domain containing 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS7 dehydrogenase/reductase (SDR family) member 7
EML3 echinoderm microtubule associated protein like 3
ENAH enabled homolog (Drosophila)
ENOSF1 enolase superfamily member 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
EXO5 exonuclease 5
FHL1 four and a half LIM domains 1
FLJ10038 uncharacterized protein FLJ10038
FMO5 flavin containing monooxygenase 5
FPGS folylpolyglutamate synthase
FUBP1 far upstream element (FUSE) binding protein 1
GALK1 galactokinase 1
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GIPR gastric inhibitory polypeptide receptor
GLRX3 glutaredoxin 3
GPSM3 G-protein signaling modulator 3
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H3B histone cluster 1, H3b
HMGB3 high mobility group box 3
IL11 interleukin 11
INO80B INO80 complex subunit B
KDM7A lysine (K)-specific demethylase 7A
KLHL22 kelch-like family member 22
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MIR22HG MIR22 host gene
MKL1 megakaryoblastic leukemia (translocation) 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MPZL1 myelin protein zero-like 1
MR1 major histocompatibility complex, class I-related
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
NDE1 nudE neurodevelopment protein 1
NMT2 N-myristoyltransferase 2
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PGBD5 piggyBac transposable element derived 5
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RPS2 ribosomal protein S2
RPS28 ribosomal protein S28
SCYL2 SCY1-like 2 (S. cerevisiae)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMAD3 SMAD family member 3
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOCS2 suppressor of cytokine signaling 2
SPHK2 sphingosine kinase 2
STARD5 StAR-related lipid transfer (START) domain containing 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
THBS3 thrombospondin 3
TLN2 talin 2
TMEM206 transmembrane protein 206
TRAIP TRAF interacting protein
TTLL4 tubulin tyrosine ligase-like family member 4
TTLL7 tubulin tyrosine ligase-like family member 7
WAPAL wings apart-like homolog (Drosophila)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H7B zinc finger CCCH-type containing 7B
ZNF41 zinc finger protein 41
ZNF609 zinc finger protein 609
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ACPP acid phosphatase, prostate
ADM adrenomedullin
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAK1 BCL2-antagonist/killer 1
BNC2 basonuclin 2
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF159 chromosome 1 open reading frame 159
C5 complement component 5
CCDC130 coiled-coil domain containing 130
CCL27 chemokine (C-C motif) ligand 27
CD69 CD69 molecule
CD82 CD82 molecule
CES3 carboxylesterase 3
CHML choroideremia-like (Rab escort protein 2)
CISH cytokine inducible SH2-containing protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CST3 cystatin C
DDN dendrin
DENND5B DENN/MADD domain containing 5B
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMBP dynamin binding protein
DOCK4 dedicator of cytokinesis 4
DUSP2 dual specificity phosphatase 2
DUSP8 dual specificity phosphatase 8
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENO2 enolase 2 (gamma, neuronal)
ERAP2 endoplasmic reticulum aminopeptidase 2
FBXO31 F-box protein 31
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDAP1 ganglioside induced differentiation associated protein 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR27 G protein-coupled receptor 27
GRAMD1B GRAM domain containing 1B
GTF2IRD1 GTF2I repeat domain containing 1
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HP haptoglobin
HYAL3 hyaluronoglucosaminidase 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INF2 inverted formin, FH2 and WH2 domain containing
IPP intracisternal A particle-promoted polypeptide
IRS1 insulin receptor substrate 1
JMJD4 jumonji domain containing 4
KIF13B kinesin family member 13B
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LINC00597 long intergenic non-protein coding RNA 597
LOC729164 hCG1732469
LRP5 low density lipoprotein receptor-related protein 5
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP6D1 MAP6 domain containing 1
MCTP2 multiple C2 domains, transmembrane 2
MMP2 matrix metallopeptidase 2
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MVD mevalonate (diphospho) decarboxylase
MX1 MX dynamin-like GTPase 1
MYO19 myosin XIX
NARFL nuclear prelamin A recognition factor-like
NCALD neurocalcin delta
NFE2L3 nuclear factor, erythroid 2-like 3
NKX3-2 NK3 homeobox 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PARG poly (ADP-ribose) glycohydrolase
PDLIM1 PDZ and LIM domain 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIPOX pipecolic acid oxidase
PLSCR4 phospholipid scramblase 4
PROS1 protein S (alpha)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOB ras homolog family member B
RPAP1 RNA polymerase II associated protein 1
RPL26 ribosomal protein L26
RUSC2 RUN and SH3 domain containing 2
SCAMP5 secretory carrier membrane protein 5
SH3GL1 SH3-domain GRB2-like 1
SPATA20 spermatogenesis associated 20
STAP1 signal transducing adaptor family member 1
STX11 syntaxin 11
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBC1D17 TBC1 domain family, member 17
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPM3 tropomyosin 3
TRIM25 tripartite motif containing 25
TSPAN5 tetraspanin 5
TUBA3C tubulin, alpha 3c
TUBB2A tubulin, beta 2A class IIa
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UPP1 uridine phosphorylase 1
YY2 YY2 transcription factor
ZNF222 zinc finger protein 222
ZNF254 zinc finger protein 254
ZNF506 zinc finger protein 506
ZNF552 zinc finger protein 552