betulinic acid-4181 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the betulinic acid-4181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAM8 ADAM metallopeptidase domain 8
AHNAK AHNAK nucleoprotein
AKAP1 A kinase (PRKA) anchor protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ALDOB aldolase B, fructose-bisphosphate
AQP7 aquaporin 7
ARHGAP24 Rho GTPase activating protein 24
ATAT1 alpha tubulin acetyltransferase 1
BCAN brevican
C8A complement component 8, alpha polypeptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC134 coiled-coil domain containing 134
CCL19 chemokine (C-C motif) ligand 19
CDC42 cell division cycle 42
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
CRHR2 corticotropin releasing hormone receptor 2
CSN2 casein beta
CST1 cystatin SN
CXCL8 chemokine (C-X-C motif) ligand 8
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DPF1 D4, zinc and double PHD fingers family 1
DVL2 dishevelled segment polarity protein 2
EFNB3 ephrin-B3
EIF1 eukaryotic translation initiation factor 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELP6 elongator acetyltransferase complex subunit 6
ERICH1 glutamate-rich 1
FKRP fukutin related protein
GBP1 guanylate binding protein 1, interferon-inducible
GIPC2 GIPC PDZ domain containing family, member 2
GLRX glutaredoxin (thioltransferase)
GP2 glycoprotein 2 (zymogen granule membrane)
HHAT hedgehog acyltransferase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA10 homeobox A10
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL36G interleukin 36, gamma
IPO5 importin 5
ITGB8 integrin, beta 8
JPH3 junctophilin 3
LAMB4 laminin, beta 4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMO3 LIM domain only 3 (rhombotin-like 2)
LTBP4 latent transforming growth factor beta binding protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MEP1B meprin A, beta
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP11 matrix metallopeptidase 11
MR1 major histocompatibility complex, class I-related
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1X metallothionein 1X
MYBPC3 myosin binding protein C, cardiac
MYO7A myosin VIIA
MYOZ1 myozenin 1
NDRG2 NDRG family member 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NOD2 nucleotide-binding oligomerization domain containing 2
NPY neuropeptide Y
NRF1 nuclear respiratory factor 1
PCDH8 protocadherin 8
PIGR polymeric immunoglobulin receptor
PILRA paired immunoglobin-like type 2 receptor alpha
PKNOX2 PBX/knotted 1 homeobox 2
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
POU5F1B POU class 5 homeobox 1B
POU6F2 POU class 6 homeobox 2
PTPRD protein tyrosine phosphatase, receptor type, D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC35G2 solute carrier family 35, member G2
SLC6A16 solute carrier family 6, member 16
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNJ2 synaptojanin 2
TDRD12 tudor domain containing 12
TLX3 T-cell leukemia homeobox 3
TMOD1 tropomodulin 1
TSC22D2 TSC22 domain family, member 2
UBXN1 UBX domain protein 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
YY2 YY2 transcription factor
ZER1 zyg-11 related, cell cycle regulator
ZNF711 zinc finger protein 711
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP4 Rho GTPase activating protein 4
ATG10 autophagy related 10
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIRC7 baculoviral IAP repeat containing 7
C1ORF105 chromosome 1 open reading frame 105
C3AR1 complement component 3a receptor 1
CCDC71 coiled-coil domain containing 71
CCDC85C coiled-coil domain containing 85C
CD53 CD53 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP70 cilia and flagella associated protein 70
CNTFR ciliary neurotrophic factor receptor
COL19A1 collagen, type XIX, alpha 1
CRLF1 cytokine receptor-like factor 1
CRMP1 collapsin response mediator protein 1
CUZD1 CUB and zona pellucida-like domains 1
DBF4B DBF4 zinc finger B
DNAH17 dynein, axonemal, heavy chain 17
ERCC2 excision repair cross-complementation group 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FGF16 fibroblast growth factor 16
FOXI1 forkhead box I1
G6PC2 glucose-6-phosphatase, catalytic, 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR63 G protein-coupled receptor 63
GTDC1 glycosyltransferase-like domain containing 1
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HLA-J major histocompatibility complex, class I, J (pseudogene)
ITGA8 integrin, alpha 8
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KEL Kell blood group, metallo-endopeptidase
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLC2 kinesin light chain 2
LHX3 LIM homeobox 3
LINC00341 long intergenic non-protein coding RNA 341
LRP2 low density lipoprotein receptor-related protein 2
MAL mal, T-cell differentiation protein
MAPK10 mitogen-activated protein kinase 10
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MUC3A mucin 3A, cell surface associated
NNAT neuronatin
NPY6R neuropeptide Y receptor Y6 (pseudogene)
ONECUT1 one cut homeobox 1
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PLXNB3 plexin B3
POM121 POM121 transmembrane nucleoporin
POU4F2 POU class 4 homeobox 2
PQLC2 PQ loop repeat containing 2
PRAMEF11 PRAME family member 11
PRF1 perforin 1 (pore forming protein)
PRKCE protein kinase C, epsilon
PRSS53 protease, serine, 53
PSG4 pregnancy specific beta-1-glycoprotein 4
RAD54L2 RAD54-like 2 (S. cerevisiae)
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF32 ring finger protein 32
RORC RAR-related orphan receptor C
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETBP1 SET binding protein 1
SLC12A9 solute carrier family 12, member 9
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLN sarcolipin
SPTA1 spectrin, alpha, erythrocytic 1
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TCEAL2 transcription elongation factor A (SII)-like 2
TGFBR1 transforming growth factor, beta receptor 1
TLR2 toll-like receptor 2
TPSG1 tryptase gamma 1
VN1R1 vomeronasal 1 receptor 1
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF205 zinc finger protein 205
ZNF329 zinc finger protein 329
ZSWIM1 zinc finger, SWIM-type containing 1