bezafibrate-1275 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bezafibrate-1275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMC7 armadillo repeat containing 7
ATG12 autophagy related 12
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAD BCL2-associated agonist of cell death
BCL2L2 BCL2-like 2
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C16ORF59 chromosome 16 open reading frame 59
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPN3 calpain 3, (p94)
CD1D CD1d molecule
CD52 CD52 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CNTLN centlein, centrosomal protein
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRMP1 collapsin response mediator protein 1
CRYZ crystallin, zeta (quinone reductase)
CSE1L CSE1 chromosome segregation 1-like (yeast)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ELOVL5 ELOVL fatty acid elongase 5
EMC1 ER membrane protein complex subunit 1
EML3 echinoderm microtubule associated protein like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRRA estrogen-related receptor alpha
FAM105A family with sequence similarity 105, member A
FAM13A family with sequence similarity 13, member A
FAM50B family with sequence similarity 50, member B
FCAR Fc fragment of IgA receptor
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLUD2 glutamate dehydrogenase 2
GM2A GM2 ganglioside activator
GOSR2 golgi SNAP receptor complex member 2
HCRP1 hepatocellular carcinoma-related HCRP1
HRH1 histamine receptor H1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL3RA interleukin 3 receptor, alpha (low affinity)
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5K inositol polyphosphate-5-phosphatase K
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDM8 lysine (K)-specific demethylase 8
LIMK2 LIM domain kinase 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MRC2 mannose receptor, C type 2
MTAP methylthioadenosine phosphorylase
NEK3 NIMA-related kinase 3
NFS1 NFS1 cysteine desulfurase
NFYA nuclear transcription factor Y, alpha
NOTCH2 notch 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PDGFB platelet-derived growth factor beta polypeptide
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20L1 PHD finger protein 20-like 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLIN2 perilipin 2
PSD4 pleckstrin and Sec7 domain containing 4
RCAN1 regulator of calcineurin 1
RFXAP regulatory factor X-associated protein
RNFT1 ring finger protein, transmembrane 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SCARB2 scavenger receptor class B, member 2
SH3BP2 SH3-domain binding protein 2
SKIL SKI-like proto-oncogene
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAI1 snail family zinc finger 1
SNX19 sorting nexin 19
SPAST spastin
SPATA2L spermatogenesis associated 2-like
SSBP3 single stranded DNA binding protein 3
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBCCD1 TBCC domain containing 1
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TMCC1 transmembrane and coiled-coil domain family 1
TMEM242 transmembrane protein 242
TMEM5 transmembrane protein 5
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM1 tropomyosin 1 (alpha)
TRDMT1 tRNA aspartic acid methyltransferase 1
UTRN utrophin
VARS valyl-tRNA synthetase
WDR33 WD repeat domain 33
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF10 zinc finger protein 10
ZNF215 zinc finger protein 215
ZNF277 zinc finger protein 277
ZNF444 zinc finger protein 444
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACVR2B activin A receptor, type IIB
AGO4 argonaute RISC catalytic component 4
AHR aryl hydrocarbon receptor
ANAPC2 anaphase promoting complex subunit 2
ANKRD40 ankyrin repeat domain 40
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASCC1 activating signal cointegrator 1 complex subunit 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BOLA1 bolA family member 1
BRPF1 bromodomain and PHD finger containing, 1
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCS copper chaperone for superoxide dismutase
CEP70 centrosomal protein 70kDa
CHKB choline kinase beta
CHMP7 charged multivesicular body protein 7
CINP cyclin-dependent kinase 2 interacting protein
CLSPN claspin
CPPED1 calcineurin-like phosphoesterase domain containing 1
DUSP8 dual specificity phosphatase 8
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETV4 ets variant 4
FAM127A family with sequence similarity 127, member A
FAM53B family with sequence similarity 53, member B
FBRS fibrosin
FHOD1 formin homology 2 domain containing 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FPGS folylpolyglutamate synthase
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GMEB1 glucocorticoid modulatory element binding protein 1
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2BF histone cluster 1, H2bf
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFITM3 interferon induced transmembrane protein 3
IGFLR1 IGF-like family receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0556 KIAA0556
KPTN kaptin (actin binding protein)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAP1S microtubule-associated protein 1S
MBTD1 mbt domain containing 1
MCOLN1 mucolipin 1
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MLYCD malonyl-CoA decarboxylase
MNT MAX network transcriptional repressor
MTERF4 mitochondrial transcription termination factor 4
MTRF1 mitochondrial translational release factor 1
MYO19 myosin XIX
NLRX1 NLR family member X1
NOTCH1 notch 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSD1 nuclear receptor binding SET domain protein 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G12A phospholipase A2, group XIIA
PNKP polynucleotide kinase 3'-phosphatase
PYCR1 pyrroline-5-carboxylate reductase 1
RAB33B RAB33B, member RAS oncogene family
RHOBTB1 Rho-related BTB domain containing 1
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPA4 replication protein A4, 30kDa
RPL39L ribosomal protein L39-like
SCAI suppressor of cancer cell invasion
SDF2L1 stromal cell-derived factor 2-like 1
SETD6 SET domain containing 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNIP1 Smad nuclear interacting protein 1
SPATS2 spermatogenesis associated, serine-rich 2
TESC tescalcin
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TMEM62 transmembrane protein 62
TMOD3 tropomodulin 3 (ubiquitous)
TRIM16 tripartite motif containing 16
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPS1 trichorhinophalangeal syndrome I
TSSC4 tumor suppressing subtransferable candidate 4
TUBA3C tubulin, alpha 3c
TUFT1 tuftelin 1
UBE2O ubiquitin-conjugating enzyme E2O
VASP vasodilator-stimulated phosphoprotein
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H3 zinc finger CCCH-type containing 3
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF551 zinc finger protein 551