bezafibrate-2630 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bezafibrate-2630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAP2 ArfGAP with dual PH domains 2
AIM1L absent in melanoma 1-like
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APAF1 apoptotic peptidase activating factor 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C3 complement component 3
CA4 carbonic anhydrase IV
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD14 caspase recruitment domain family, member 14
CCDC57 coiled-coil domain containing 57
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHN2 chimerin 2
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO7 coronin 7
CPNE7 copine VII
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPK2 death-associated protein kinase 2
DLX2 distal-less homeobox 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DTNA dystrobrevin, alpha
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR1 fibroblast growth factor receptor 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP8 FK506 binding protein 8, 38kDa
GIPR gastric inhibitory polypeptide receptor
GLG1 golgi glycoprotein 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR182 G protein-coupled receptor 182
GYG2 glycogenin 2
HAMP hepcidin antimicrobial peptide
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2BN histone cluster 1, H2bn
HYAL1 hyaluronoglucosaminidase 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL27RA interleukin 27 receptor, alpha
INTS1 integrator complex subunit 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLF9 Kruppel-like factor 9
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA3 melanoma antigen family A3
MINK1 misshapen-like kinase 1
MPL MPL proto-oncogene, thrombopoietin receptor
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC8 mucin 8
NPR2 natriuretic peptide receptor 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NT5M 5',3'-nucleotidase, mitochondrial
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARVA parvin, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAC4 placenta-specific 4
PLAT plasminogen activator, tissue
PLD3 phospholipase D family, member 3
PRAMEF11 PRAME family member 11
PRPH2 peripherin 2 (retinal degeneration, slow)
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTPRU protein tyrosine phosphatase, receptor type, U
RARA retinoic acid receptor, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SAFB scaffold attachment factor B
SCAI suppressor of cancer cell invasion
SCARB1 scavenger receptor class B, member 1
SDC2 syndecan 2
SDPR serum deprivation response
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SND1-IT1 SND1 intronic transcript 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STARD8 StAR-related lipid transfer (START) domain containing 8
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLDC1 TBC/LysM-associated domain containing 1
TMEM176A transmembrane protein 176A
TMEM53 transmembrane protein 53
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM36 tripartite motif containing 36
VASH2 vasohibin 2
VCX2 variable charge, X-linked 2
WNT6 wingless-type MMTV integration site family, member 6
WSB1 WD repeat and SOCS box containing 1
ZNF204P zinc finger protein 204, pseudogene
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76
ZYX zyxin

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
AIM1 absent in melanoma 1
ANKRD28 ankyrin repeat domain 28
BATF basic leucine zipper transcription factor, ATF-like
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
C5AR2 complement component 5a receptor 2
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALCOCO1 calcium binding and coiled-coil domain 1
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRELD1 cysteine-rich with EGF-like domains 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL15 F-box and leucine-rich repeat protein 15
FKBP5 FK506 binding protein 5
GCA grancalcin, EF-hand calcium binding protein
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GRAMD3 GRAM domain containing 3
GTF2I general transcription factor IIi
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC10 homeobox C10
IL4R interleukin 4 receptor
IREB2 iron-responsive element binding protein 2
JRKL JRK-like
KATNBL1 katanin p80 subunit B-like 1
KLF11 Kruppel-like factor 11
KLF3 Kruppel-like factor 3 (basic)
KRI1 KRI1 homolog (S. cerevisiae)
LARP6 La ribonucleoprotein domain family, member 6
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHX1 LIM homeobox 1
LIAS lipoic acid synthetase
LINC00339 long intergenic non-protein coding RNA 339
LNPEP leucyl/cystinyl aminopeptidase
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
METTL2B methyltransferase like 2B
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NUPL2 nucleoporin like 2
OGFRL1 opioid growth factor receptor-like 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGPEP1 pyroglutamyl-peptidase I
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNPLA6 patatin-like phospholipase domain containing 6
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
PRKX protein kinase, X-linked
PRMT7 protein arginine methyltransferase 7
PRSS22 protease, serine, 22
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASA2 RAS p21 protein activator 2
RECQL4 RecQ protein-like 4
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF141 ring finger protein 141
RPGR retinitis pigmentosa GTPase regulator
SHPK sedoheptulokinase
SLC16A6 solute carrier family 16, member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STAG3 stromal antigen 3
STX5 syntaxin 5
THRAP3 thyroid hormone receptor associated protein 3
TICAM1 toll-like receptor adaptor molecule 1
TM7SF3 transmembrane 7 superfamily member 3
TMC7 transmembrane channel-like 7
TMEM183A transmembrane protein 183A
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
ULK1 unc-51 like autophagy activating kinase 1
WDR4 WD repeat domain 4
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP30 ZFP30 zinc finger protein