bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS1731
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Genes

133 genes differentially expressed following the bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
BNC1 basonuclin 1 5.18155
GSTM2 glutathione S-transferase mu 2 (muscle) 4.68503
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 4.49463
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 3.23861
SNHG1 small nucleolar RNA host gene 1 2.75789
MYEOV2 myeloma overexpressed 2 2.75789
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.75789
SGK3 serum/glucocorticoid regulated kinase family, member 3 2.75789
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 2.75789
CANX calnexin 2.75789
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 2.75789
GSTO1 glutathione S-transferase omega 1 2.54466
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 2.54466
GSTM1 glutathione S-transferase mu 1 2.19742
PHGDH phosphoglycerate dehydrogenase 1.93332
CCNL2 cyclin L2 1.33914
TSC22D1 TSC22 domain family, member 1 0.790056
IQGAP2 IQ motif containing GTPase activating protein 2 0.790056
TRA2B transformer 2 beta homolog (Drosophila) 0.790056
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.790056
COL7A1 collagen, type VII, alpha 1 0.790056
MBNL1 muscleblind-like splicing regulator 1 0.790056
PYCR2 pyrroline-5-carboxylate reductase family, member 2 0.790056
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.790056
C12ORF57 chromosome 12 open reading frame 57 0.790056
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.790056
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.790056
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.790056
CDK16 cyclin-dependent kinase 16 0.790056
SEC11C SEC11 homolog C (S. cerevisiae) 0.790056
PIAS4 protein inhibitor of activated STAT, 4 0.790056
PPP1R37 protein phosphatase 1, regulatory subunit 37 0.790056
KARS lysyl-tRNA synthetase 0.790056
PAM peptidylglycine alpha-amidating monooxygenase 0.790056
ODC1 ornithine decarboxylase 1 0.790056
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.790056
GNS glucosamine (N-acetyl)-6-sulfatase 0.722335
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.722335
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.722335
DHPS deoxyhypusine synthase 0.609711
RPS27L ribosomal protein S27-like 0.50108
SDS serine dehydratase 0.50108
CRELD2 cysteine-rich with EGF-like domains 2 0.50108
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.50108
KIAA1324 KIAA1324 0.50108
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.50108
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.50108
TSPAN13 tetraspanin 13 0.50108
GJB4 gap junction protein, beta 4, 30.3kDa 0.50108
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.50108
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.50108
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.50108
SPAST spastin 0.369792
MYO7A myosin VIIA 0.3662
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.356471
BST2 bone marrow stromal cell antigen 2 0.356471
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.264339
TMEM189 transmembrane protein 189 0.264339
QTRT1 queuine tRNA-ribosyltransferase 1 0.233802
TNRC6A trinucleotide repeat containing 6A 0.232302
CLIP4 CAP-GLY domain containing linker protein family, member 4 0.232302

decreased expression

Symbol Name Standardized Value
TECR trans-2,3-enoyl-CoA reductase -0.371041
GC group-specific component (vitamin D binding protein) -0.333786
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.333786
CD81 CD81 molecule -0.326776
TGM2 transglutaminase 2 -0.303318
AP4M1 adaptor-related protein complex 4, mu 1 subunit -0.291998
CCNI cyclin I -0.291998
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 -0.291998
NONO non-POU domain containing, octamer-binding -0.291998
AK3 adenylate kinase 3 -0.291998
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.291998
CENPF centromere protein F, 350/400kDa -0.291998
STK39 serine threonine kinase 39 -0.291998
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -0.291998
AASS aminoadipate-semialdehyde synthase -0.291998
TMEM97 transmembrane protein 97 -0.291998
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.291998
METTL7A methyltransferase like 7A -0.291998
GJB1 gap junction protein, beta 1, 32kDa -0.291998
PBX3 pre-B-cell leukemia homeobox 3 -0.291998
GIF gastric intrinsic factor (vitamin B synthesis) -0.291998
FBXO36 F-box protein 36 -0.291998
SCRN2 secernin 2 -0.291998
EIF4H eukaryotic translation initiation factor 4H -0.291998
TEKT1 tektin 1 -0.291998
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.291998
MAT2A methionine adenosyltransferase II, alpha -0.291998
TPD52L2 tumor protein D52-like 2 -0.291998
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -0.291998
AP4B1 adaptor-related protein complex 4, beta 1 subunit -0.277585
TFCP2L1 transcription factor CP2-like 1 -0.27755
NCOA6 nuclear receptor coactivator 6 -0.272668
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.272668
RPL7A ribosomal protein L7a -0.27082
UBAP2 ubiquitin associated protein 2 -0.246202
DDB1 damage-specific DNA binding protein 1, 127kDa -0.246202
CALM3 calmodulin 3 (phosphorylase kinase, delta) -0.246202
TTC7B tetratricopeptide repeat domain 7B -0.211806
CBX3 chromobox homolog 3 -0.211806
MBD2 methyl-CpG binding domain protein 2 -0.211806
DGCR6 DiGeorge syndrome critical region gene 6 -0.209886
AUH AU RNA binding protein/enoyl-CoA hydratase -0.209886
PLA2G1B phospholipase A2, group IB (pancreas) -0.209886
IMMT inner membrane protein, mitochondrial -0.198137
AHCYL1 adenosylhomocysteinase-like 1 -0.198137
ALPI alkaline phosphatase, intestinal -0.198137
RAB3D RAB3D, member RAS oncogene family -0.198137
ISOC1 isochorismatase domain containing 1 -0.198137
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -0.198137
CD164 CD164 molecule, sialomucin -0.198137
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.198137
SUN1 Sad1 and UNC84 domain containing 1 -0.198137
RND2 Rho family GTPase 2 -0.198137
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.198137
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.198137
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.198137
TRAM1 translocation associated membrane protein 1 -0.198137
GJB2 gap junction protein, beta 2, 26kDa -0.198137
PPAP2B phosphatidic acid phosphatase type 2B -0.198137
NCOR1 nuclear receptor corepressor 1 -0.198137
UFM1 ubiquitin-fold modifier 1 -0.117984
GSN gelsolin -0.117984
NUCB2 nucleobindin 2 -0.117984
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.117984
PDZD11 PDZ domain containing 11 -0.094556
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.094556
NTN1 netrin 1 -0.094556
SECISBP2L SECIS binding protein 2-like -0.094556
GPC1 glypican 1 -0.041697
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -0.03624
EGF epidermal growth factor -0.03624
SWI5 SWI5 recombination repair homolog (yeast) -0.03624