Dataset | GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations |
Category | transcriptomics |
Type | transcription factor perturbation |
Description | transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus) |
External Link | http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS1731 |
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133 genes differentially expressed following the bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
Symbol | Name | Standardized Value |
---|---|---|
BNC1 | basonuclin 1 | 5.18155 |
GSTM2 | glutathione S-transferase mu 2 (muscle) | 4.68503 |
COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | 4.49463 |
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 3.23861 |
SNHG1 | small nucleolar RNA host gene 1 | 2.75789 |
MYEOV2 | myeloma overexpressed 2 | 2.75789 |
P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | 2.75789 |
SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 2.75789 |
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 2.75789 |
CANX | calnexin | 2.75789 |
ASB11 | ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase | 2.75789 |
GSTO1 | glutathione S-transferase omega 1 | 2.54466 |
USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) | 2.54466 |
GSTM1 | glutathione S-transferase mu 1 | 2.19742 |
PHGDH | phosphoglycerate dehydrogenase | 1.93332 |
CCNL2 | cyclin L2 | 1.33914 |
TSC22D1 | TSC22 domain family, member 1 | 0.790056 |
IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.790056 |
TRA2B | transformer 2 beta homolog (Drosophila) | 0.790056 |
KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.790056 |
COL7A1 | collagen, type VII, alpha 1 | 0.790056 |
MBNL1 | muscleblind-like splicing regulator 1 | 0.790056 |
PYCR2 | pyrroline-5-carboxylate reductase family, member 2 | 0.790056 |
SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.790056 |
C12ORF57 | chromosome 12 open reading frame 57 | 0.790056 |
TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 0.790056 |
HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.790056 |
SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.790056 |
CDK16 | cyclin-dependent kinase 16 | 0.790056 |
SEC11C | SEC11 homolog C (S. cerevisiae) | 0.790056 |
PIAS4 | protein inhibitor of activated STAT, 4 | 0.790056 |
PPP1R37 | protein phosphatase 1, regulatory subunit 37 | 0.790056 |
KARS | lysyl-tRNA synthetase | 0.790056 |
PAM | peptidylglycine alpha-amidating monooxygenase | 0.790056 |
ODC1 | ornithine decarboxylase 1 | 0.790056 |
UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.790056 |
GNS | glucosamine (N-acetyl)-6-sulfatase | 0.722335 |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.722335 |
LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.722335 |
DHPS | deoxyhypusine synthase | 0.609711 |
RPS27L | ribosomal protein S27-like | 0.50108 |
SDS | serine dehydratase | 0.50108 |
CRELD2 | cysteine-rich with EGF-like domains 2 | 0.50108 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.50108 |
KIAA1324 | KIAA1324 | 0.50108 |
PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.50108 |
NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 0.50108 |
TSPAN13 | tetraspanin 13 | 0.50108 |
GJB4 | gap junction protein, beta 4, 30.3kDa | 0.50108 |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.50108 |
POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.50108 |
CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.50108 |
SPAST | spastin | 0.369792 |
MYO7A | myosin VIIA | 0.3662 |
SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.356471 |
BST2 | bone marrow stromal cell antigen 2 | 0.356471 |
NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 0.264339 |
TMEM189 | transmembrane protein 189 | 0.264339 |
QTRT1 | queuine tRNA-ribosyltransferase 1 | 0.233802 |
TNRC6A | trinucleotide repeat containing 6A | 0.232302 |
CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.232302 |
Symbol | Name | Standardized Value |
---|---|---|
TECR | trans-2,3-enoyl-CoA reductase | -0.371041 |
GC | group-specific component (vitamin D binding protein) | -0.333786 |
VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.333786 |
CD81 | CD81 molecule | -0.326776 |
TGM2 | transglutaminase 2 | -0.303318 |
AP4M1 | adaptor-related protein complex 4, mu 1 subunit | -0.291998 |
CCNI | cyclin I | -0.291998 |
IGDCC4 | immunoglobulin superfamily, DCC subclass, member 4 | -0.291998 |
NONO | non-POU domain containing, octamer-binding | -0.291998 |
AK3 | adenylate kinase 3 | -0.291998 |
MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.291998 |
CENPF | centromere protein F, 350/400kDa | -0.291998 |
STK39 | serine threonine kinase 39 | -0.291998 |
HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.291998 |
AASS | aminoadipate-semialdehyde synthase | -0.291998 |
TMEM97 | transmembrane protein 97 | -0.291998 |
SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.291998 |
METTL7A | methyltransferase like 7A | -0.291998 |
GJB1 | gap junction protein, beta 1, 32kDa | -0.291998 |
PBX3 | pre-B-cell leukemia homeobox 3 | -0.291998 |
GIF | gastric intrinsic factor (vitamin B synthesis) | -0.291998 |
FBXO36 | F-box protein 36 | -0.291998 |
SCRN2 | secernin 2 | -0.291998 |
EIF4H | eukaryotic translation initiation factor 4H | -0.291998 |
TEKT1 | tektin 1 | -0.291998 |
NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.291998 |
MAT2A | methionine adenosyltransferase II, alpha | -0.291998 |
TPD52L2 | tumor protein D52-like 2 | -0.291998 |
PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | -0.291998 |
AP4B1 | adaptor-related protein complex 4, beta 1 subunit | -0.277585 |
TFCP2L1 | transcription factor CP2-like 1 | -0.27755 |
NCOA6 | nuclear receptor coactivator 6 | -0.272668 |
MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.272668 |
RPL7A | ribosomal protein L7a | -0.27082 |
UBAP2 | ubiquitin associated protein 2 | -0.246202 |
DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.246202 |
CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.246202 |
TTC7B | tetratricopeptide repeat domain 7B | -0.211806 |
CBX3 | chromobox homolog 3 | -0.211806 |
MBD2 | methyl-CpG binding domain protein 2 | -0.211806 |
DGCR6 | DiGeorge syndrome critical region gene 6 | -0.209886 |
AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.209886 |
PLA2G1B | phospholipase A2, group IB (pancreas) | -0.209886 |
IMMT | inner membrane protein, mitochondrial | -0.198137 |
AHCYL1 | adenosylhomocysteinase-like 1 | -0.198137 |
ALPI | alkaline phosphatase, intestinal | -0.198137 |
RAB3D | RAB3D, member RAS oncogene family | -0.198137 |
ISOC1 | isochorismatase domain containing 1 | -0.198137 |
ATP5F1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 | -0.198137 |
CD164 | CD164 molecule, sialomucin | -0.198137 |
HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.198137 |
SUN1 | Sad1 and UNC84 domain containing 1 | -0.198137 |
RND2 | Rho family GTPase 2 | -0.198137 |
HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.198137 |
DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.198137 |
CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.198137 |
TRAM1 | translocation associated membrane protein 1 | -0.198137 |
GJB2 | gap junction protein, beta 2, 26kDa | -0.198137 |
PPAP2B | phosphatidic acid phosphatase type 2B | -0.198137 |
NCOR1 | nuclear receptor corepressor 1 | -0.198137 |
UFM1 | ubiquitin-fold modifier 1 | -0.117984 |
GSN | gelsolin | -0.117984 |
NUCB2 | nucleobindin 2 | -0.117984 |
RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.117984 |
PDZD11 | PDZ domain containing 11 | -0.094556 |
ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.094556 |
NTN1 | netrin 1 | -0.094556 |
SECISBP2L | SECIS binding protein 2-like | -0.094556 |
GPC1 | glypican 1 | -0.041697 |
HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.03624 |
EGF | epidermal growth factor | -0.03624 |
SWI5 | SWI5 recombination repair homolog (yeast) | -0.03624 |