| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the bicuculline-2139 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| AFF3 | AF4/FMR2 family, member 3 |
| AGTPBP1 | ATP/GTP binding protein 1 |
| ARMC4 | armadillo repeat containing 4 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASMT | acetylserotonin O-methyltransferase |
| ATP13A2 | ATPase type 13A2 |
| B9D2 | B9 protein domain 2 |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CADM3 | cell adhesion molecule 3 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLMN | calmin (calponin-like, transmembrane) |
| CNTNAP2 | contactin associated protein-like 2 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| COPE | coatomer protein complex, subunit epsilon |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CREM | cAMP responsive element modulator |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSNK1E | casein kinase 1, epsilon |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DLG3 | discs, large homolog 3 (Drosophila) |
| DPEP2 | dipeptidase 2 |
| DUS2 | dihydrouridine synthase 2 |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM65A | family with sequence similarity 65, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FYB | FYN binding protein |
| GALC | galactosylceramidase |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GP6 | glycoprotein VI (platelet) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR137 | G protein-coupled receptor 137 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HOXA3 | homeobox A3 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRC6 | leucine rich repeat containing 6 |
| MED25 | mediator complex subunit 25 |
| MORN1 | MORN repeat containing 1 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO1B | myosin IB |
| NARFL | nuclear prelamin A recognition factor-like |
| NOV | nephroblastoma overexpressed |
| NPEPL1 | aminopeptidase-like 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PADI4 | peptidyl arginine deiminase, type IV |
| PCDH9 | protocadherin 9 |
| PDLIM5 | PDZ and LIM domain 5 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PID1 | phosphotyrosine interaction domain containing 1 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTAFR | platelet-activating factor receptor |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL10 | ribosomal protein L10 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC35G2 | solute carrier family 35, member G2 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SRPK2 | SRSF protein kinase 2 |
| STX2 | syntaxin 2 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPC2 | transient receptor potential cation channel, subfamily C, member 2, pseudogene |
| TUBA4B | tubulin, alpha 4b |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF234 | zinc finger protein 234 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BBC3 | BCL2 binding component 3 |
| BNC2 | basonuclin 2 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTN1 | contactin 1 |
| CORT | cortistatin |
| CTSD | cathepsin D |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DEPDC5 | DEP domain containing 5 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DOLK | dolichol kinase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM63A | family with sequence similarity 63, member A |
| FBRS | fibrosin |
| FMO4 | flavin containing monooxygenase 4 |
| FOXN2 | forkhead box N2 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AM | histone cluster 1, H2am |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL11RA | interleukin 11 receptor, alpha |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0753 | KIAA0753 |
| KLHL26 | kelch-like family member 26 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEH1 | melanoma antigen family H1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NABP1 | nucleic acid binding protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NLK | nemo-like kinase |
| PARG | poly (ADP-ribose) glycohydrolase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRAF2 | PRA1 domain family, member 2 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERTAD3 | SERTA domain containing 3 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP140L | SP140 nuclear body protein-like |
| SPAG4 | sperm associated antigen 4 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STX1A | syntaxin 1A (brain) |
| SV2A | synaptic vesicle glycoprotein 2A |
| SYCP2 | synaptonemal complex protein 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCTN2 | tectonic family member 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLN1 | talin 1 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFB | vascular endothelial growth factor B |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF34 | zinc finger protein 34 |
