bicuculline-2796 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the bicuculline-2796 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADAM8 ADAM metallopeptidase domain 8
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARC activity-regulated cytoskeleton-associated protein
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASIC3 acid sensing (proton gated) ion channel 3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAHCC1 BAH domain and coiled-coil containing 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C11ORF80 chromosome 11 open reading frame 80
CABIN1 calcineurin binding protein 1
CALML5 calmodulin-like 5
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CC2D1A coiled-coil and C2 domain containing 1A
CD34 CD34 molecule
CD8A CD8a molecule
CLEC11A C-type lectin domain family 11, member A
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLTC clathrin, heavy chain (Hc)
CNTLN centlein, centrosomal protein
CNTN5 contactin 5
CTSF cathepsin F
CTSZ cathepsin Z
DBT dihydrolipoamide branched chain transacylase E2
DENND5B DENN/MADD domain containing 5B
DLX2 distal-less homeobox 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPYSL4 dihydropyrimidinase-like 4
DTNB dystrobrevin, beta
EFNB3 ephrin-B3
FADS2 fatty acid desaturase 2
FAM46C family with sequence similarity 46, member C
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FHL1 four and a half LIM domains 1
GRK5 G protein-coupled receptor kinase 5
HCFC1 host cell factor C1
HEXA-AS1 HEXA antisense RNA 1
HMG20B high mobility group 20B
HNMT histamine N-methyltransferase
HOXA6 homeobox A6
HPX hemopexin
IHH indian hedgehog
INE1 inactivation escape 1 (non-protein coding)
INO80B INO80 complex subunit B
ITGA10 integrin, alpha 10
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0754 KIAA0754
LDHC lactate dehydrogenase C
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MIR622 microRNA 622
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRG2 neuregulin 2
ONECUT2 one cut homeobox 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PARVB parvin, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRDX2 peroxiredoxin 2
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTRF polymerase I and transcript release factor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RB1 retinoblastoma 1
RHOH ras homolog family member H
ROM1 retinal outer segment membrane protein 1
SH3BP2 SH3-domain binding protein 2
SIAH1 siah E3 ubiquitin protein ligase 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOGA1 suppressor of glucose, autophagy associated 1
ST5 suppression of tumorigenicity 5
STARD8 StAR-related lipid transfer (START) domain containing 8
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAOK2 TAO kinase 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THBD thrombomodulin
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TSPAN32 tetraspanin 32
TTC38 tetratricopeptide repeat domain 38
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS9D1 VPS9 domain containing 1
WDFY3 WD repeat and FYVE domain containing 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBTB7A zinc finger and BTB domain containing 7A
ZNF442 zinc finger protein 442
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCORL1 BCL6 corepressor-like 1
BSPRY B-box and SPRY domain containing
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC121 coiled-coil domain containing 121
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CCNT1 cyclin T1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLCN2 chloride channel, voltage-sensitive 2
CLEC16A C-type lectin domain family 16, member A
CMTR1 cap methyltransferase 1
CPNE1 copine I
CRABP1 cellular retinoic acid binding protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ERCC6 excision repair cross-complementation group 6
ETAA1 Ewing tumor-associated antigen 1
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGGY FGGY carbohydrate kinase domain containing
FMOD fibromodulin
GBAS glioblastoma amplified sequence
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
IGSF1 immunoglobulin superfamily, member 1
IL15RA interleukin 15 receptor, alpha
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC61 leucine rich repeat containing 61
MAN2C1 mannosidase, alpha, class 2C, member 1
MATK megakaryocyte-associated tyrosine kinase
MBIP MAP3K12 binding inhibitory protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED15 mediator complex subunit 15
METTL16 methyltransferase like 16
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NBEAL2 neurobeachin-like 2
NIPAL2 NIPA-like domain containing 2
NT5E 5'-nucleotidase, ecto (CD73)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLXNA3 plexin A3
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RHOBTB2 Rho-related BTB domain containing 2
RPL10L ribosomal protein L10-like
SCAI suppressor of cancer cell invasion
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP7 SUMO1/sentrin specific peptidase 7
SIRT6 sirtuin 6
SLC12A8 solute carrier family 12, member 8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC38A10 solute carrier family 38, member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STARD5 StAR-related lipid transfer (START) domain containing 5
STXBP2 syntaxin binding protein 2
SUN2 Sad1 and UNC84 domain containing 2
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TRIM66 tripartite motif containing 66
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZDHHC24 zinc finger, DHHC-type containing 24
ZMAT5 zinc finger, matrin-type 5
ZNF282 zinc finger protein 282
ZNF365 zinc finger protein 365
ZNF552 zinc finger protein 552
ZNF571 zinc finger protein 571