| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the bicuculline-4397 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALAS2 | 5'-aminolevulinate synthase 2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AMN | amnion associated transmembrane protein |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| ARL4D | ADP-ribosylation factor-like 4D |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CALD1 | caldesmon 1 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD209 | CD209 molecule |
| CD4 | CD4 molecule |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CELF2 | CUGBP, Elav-like family member 2 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLDN17 | claudin 17 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREBBP | CREB binding protein |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DRD2 | dopamine receptor D2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ETV5 | ets variant 5 |
| ETV7 | ets variant 7 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FRMD1 | FERM domain containing 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| GSAP | gamma-secretase activating protein |
| HAS2 | hyaluronan synthase 2 |
| HCRT | hypocretin (orexin) neuropeptide precursor |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IHH | indian hedgehog |
| IL12RB2 | interleukin 12 receptor, beta 2 |
| ITM2C | integral membrane protein 2C |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIAA0485 | uncharacterized LOC57235 |
| LAT2 | linker for activation of T cells family, member 2 |
| MDFI | MyoD family inhibitor |
| MEF2D | myocyte enhancer factor 2D |
| MUC3B | mucin 3B, cell surface associated |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NIPAL3 | NIPA-like domain containing 3 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NPTX2 | neuronal pentraxin II |
| NPY2R | neuropeptide Y receptor Y2 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OLFM1 | olfactomedin 1 |
| ONECUT1 | one cut homeobox 1 |
| OPRL1 | opiate receptor-like 1 |
| PAX8 | paired box 8 |
| PEG10 | paternally expressed 10 |
| PIGR | polymeric immunoglobulin receptor |
| PIP | prolactin-induced protein |
| PLAC4 | placenta-specific 4 |
| PLCH1 | phospholipase C, eta 1 |
| PLLP | plasmolipin |
| PLSCR4 | phospholipid scramblase 4 |
| POF1B | premature ovarian failure, 1B |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| RAB6A | RAB6A, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RPL35A | ribosomal protein L35a |
| S100A8 | S100 calcium binding protein A8 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SNX13 | sorting nexin 13 |
| SOCS7 | suppressor of cytokine signaling 7 |
| STRN3 | striatin, calmodulin binding protein 3 |
| TGM2 | transglutaminase 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNN | tenascin N |
| TRIM10 | tripartite motif containing 10 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| ULBP1 | UL16 binding protein 1 |
| VPS9D1 | VPS9 domain containing 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WSCD1 | WSC domain containing 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF507 | zinc finger protein 507 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AFAP1 | actin filament associated protein 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC186 | coiled-coil domain containing 186 |
| CCNO | cyclin O |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CPNE7 | copine VII |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYGC | crystallin, gamma C |
| CUEDC1 | CUE domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DIXDC1 | DIX domain containing 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLT4 | fms-related tyrosine kinase 4 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HOXA4 | homeobox A4 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| IRF9 | interferon regulatory factor 9 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LHX6 | LIM homeobox 6 |
| LMNB1 | lamin B1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAGEF1 | melanoma antigen family F1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MTCP1 | mature T-cell proliferation 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| OSMR | oncostatin M receptor |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCDHB3 | protocadherin beta 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| PP14571 | uncharacterized LOC100130449 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRR4 | proline rich 4 (lacrimal) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RGS2 | regulator of G-protein signaling 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCRN3 | secernin 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPRR2B | small proline-rich protein 2B |
| SREK1IP1 | SREK1-interacting protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| UPP1 | uridine phosphorylase 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VIM | vimentin |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| YY2 | YY2 transcription factor |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF211 | zinc finger protein 211 |
| ZNF286A | zinc finger protein 286A |
| ZNF428 | zinc finger protein 428 |
| ZNF552 | zinc finger protein 552 |
| ZNF623 | zinc finger protein 623 |
| ZNF696 | zinc finger protein 696 |
| ZNF816 | zinc finger protein 816 |
