| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the bicuculline-4574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADD2 | adducin 2 (beta) |
| ADRB3 | adrenoceptor beta 3 |
| AHSP | alpha hemoglobin stabilizing protein |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BBC3 | BCL2 binding component 3 |
| BMP7 | bone morphogenetic protein 7 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C2CD2L | C2CD2-like |
| C3 | complement component 3 |
| CCDC186 | coiled-coil domain containing 186 |
| CLCN1 | chloride channel, voltage-sensitive 1 |
| CLIC2 | chloride intracellular channel 2 |
| CNTNAP2 | contactin associated protein-like 2 |
| CREM | cAMP responsive element modulator |
| DACH1 | dachshund family transcription factor 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DLC1 | DLC1 Rho GTPase activating protein |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK4 | docking protein 4 |
| ESRRG | estrogen-related receptor gamma |
| EVI2A | ecotropic viral integration site 2A |
| FBXO41 | F-box protein 41 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR17 | G protein-coupled receptor 17 |
| HCFC1 | host cell factor C1 |
| HNF1B | HNF1 homeobox B |
| HOXC5 | homeobox C5 |
| HSPA12A | heat shock 70kDa protein 12A |
| IGL | immunoglobulin lambda locus |
| IL36RN | interleukin 36 receptor antagonist |
| IL5RA | interleukin 5 receptor, alpha |
| ITGA7 | integrin, alpha 7 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KIAA0040 | KIAA0040 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MBD2 | methyl-CpG binding domain protein 2 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| METTL7A | methyltransferase like 7A |
| MFAP3 | microfibrillar-associated protein 3 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MTMR3 | myotubularin related protein 3 |
| MTSS1L | metastasis suppressor 1-like |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NRG1 | neuregulin 1 |
| PALM | paralemmin |
| PCDHB3 | protocadherin beta 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PHOX2A | paired-like homeobox 2a |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| POU4F1 | POU class 4 homeobox 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RAG1 | recombination activating gene 1 |
| RGS5 | regulator of G-protein signaling 5 |
| SC5D | sterol-C5-desaturase |
| SCEL | sciellin |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SPPL2B | signal peptide peptidase like 2B |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| TEF | thyrotrophic embryonic factor |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN2 | talin 2 |
| TTC12 | tetratricopeptide repeat domain 12 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VDAC3 | voltage-dependent anion channel 3 |
| WDR59 | WD repeat domain 59 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF225 | zinc finger protein 225 |
| ZNF44 | zinc finger protein 44 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPN15 | calpain 15 |
| CDK6 | cyclin-dependent kinase 6 |
| CES3 | carboxylesterase 3 |
| CHRDL1 | chordin-like 1 |
| CLCA1 | chloride channel accessory 1 |
| CLSTN3 | calsyntenin 3 |
| CNTLN | centlein, centrosomal protein |
| DBF4B | DBF4 zinc finger B |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND2D | DENN/MADD domain containing 2D |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP9 | dual specificity phosphatase 9 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FA2H | fatty acid 2-hydroxylase |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FLCN | folliculin |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4A | histone cluster 1, H4a |
| HOXA1 | homeobox A1 |
| IFNA14 | interferon, alpha 14 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITK | IL2-inducible T-cell kinase |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF13 | Kruppel-like factor 13 |
| LAMC3 | laminin, gamma 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY96 | lymphocyte antigen 96 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MDFI | MyoD family inhibitor |
| MEGF8 | multiple EGF-like-domains 8 |
| MMRN2 | multimerin 2 |
| MTMR11 | myotubularin related protein 11 |
| MUC3B | mucin 3B, cell surface associated |
| MX1 | MX dynamin-like GTPase 1 |
| MYLK | myosin light chain kinase |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NDRG4 | NDRG family member 4 |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PEX26 | peroxisomal biogenesis factor 26 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLAC8 | placenta-specific 8 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PROX1 | prospero homeobox 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCIN | scinderin |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNHG3 | small nucleolar RNA host gene 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STX17 | syntaxin 17 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| TUBB2B | tubulin, beta 2B class IIb |
| USP19 | ubiquitin specific peptidase 19 |
| WDR4 | WD repeat domain 4 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF343 | zinc finger protein 343 |
| ZNF76 | zinc finger protein 76 |