bile Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A fluid secreted by the liver and poured into the small intestine via the bile ducts. Important constituents are conjugated bile salts, cholesterol, phospholipid, bilirubin diglucuronide, and electrolytes. Bile is alkaline due to its bicarbonate content, is golden brown to greenish yellow in color, and has a bitter taste. Bile secreted by the liver is concentrated in the gallbladder. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000121)
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Genes

164 proteins co-occuring with the tissue bile in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.21193
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.08242
GPBAR1 G protein-coupled bile acid receptor 1 1.96198
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.71092
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.70246
POGK pogo transposable element with KRAB domain 1.64907
FGF19 fibroblast growth factor 19 1.62657
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.60763
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.55309
GUSB glucuronidase, beta 1.432
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.42784
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.37864
CCK cholecystokinin 1.34089
DHRS9 dehydrogenase/reductase (SDR family) member 9 1.30478
OR51F1 olfactory receptor, family 51, subfamily F, member 1 (gene/pseudogene) 1.25681
ALPPL2 alkaline phosphatase, placental-like 2 1.23985
ALPL alkaline phosphatase, liver/bone/kidney 1.2394
ALPP alkaline phosphatase, placental 1.23851
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.21668
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.20912
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.19356
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.17402
SLC51A solute carrier family 51, alpha subunit 1.11243
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 1.10624
GCG glucagon 1.08501
FABP6 fatty acid binding protein 6, ileal 1.07618
ALB albumin 1.03478
CD79A CD79a molecule, immunoglobulin-associated alpha 0.958585
TMEM126A transmembrane protein 126A 0.913933
HMX2 H6 family homeobox 2 0.8601
SLC51B solute carrier family 51, beta subunit 0.843706
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 0.837833
MRPS15 mitochondrial ribosomal protein S15 0.824431
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.820666
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.776079
GGT1 gamma-glutamyltransferase 1 0.773174
CSN1S1 casein alpha s1 0.761984
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.758259
NT5E 5'-nucleotidase, ecto (CD73) 0.757432
MLN motilin 0.757432
PNLIP pancreatic lipase 0.755777
HRC histidine rich calcium binding protein 0.742152
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.73803
INS insulin 0.736382
NR1I3 nuclear receptor subfamily 1, group I, member 3 0.733089
DNAH8 dynein, axonemal, heavy chain 8 0.732265
SST somatostatin 0.719113
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.705583
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.684735
TBCC tubulin folding cofactor C 0.680248
ARSH arylsulfatase family, member H 0.679433
MRPS7 mitochondrial ribosomal protein S7 0.666402
TRIM37 tripartite motif containing 37 0.665588
KRTDAP keratinocyte differentiation-associated protein 0.663149
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.654618
MUC2 mucin 2, oligomeric mucus/gel-forming 0.648127
MTTP microsomal triglyceride transfer protein 0.609332
CCKAR cholecystokinin A receptor 0.606916
JUN jun proto-oncogene 0.605709
PLA2G1B phospholipase A2, group IB (pancreas) 0.575216
GIF gastric intrinsic factor (vitamin B synthesis) 0.569622
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.566828
ACOX2 acyl-CoA oxidase 2, branched chain 0.558059
CDX2 caudal type homeobox 2 0.552888
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.549312
APOA1 apolipoprotein A-I 0.546533
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 0.541773
PPY pancreatic polypeptide 0.541377
ATP13A1 ATPase type 13A1 0.540188
KLB klotho beta 0.533856
PNMA1 paraneoplastic Ma antigen 1 0.526744
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.522405
CDX1 caudal type homeobox 1 0.516891
AQP12A aquaporin 12A 0.505495
TNN tenascin N 0.505102
APOB apolipoprotein B 0.503141
ACOX3 acyl-CoA oxidase 3, pristanoyl 0.501965
SLC35E2B solute carrier family 35, member E2B 0.501182
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.484766
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 0.476589
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.472704
BAAT bile acid CoA:amino acid N-acyltransferase 0.4634
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.450657
AKR1D1 aldo-keto reductase family 1, member D1 0.447961
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.442194
ERH enhancer of rudimentary homolog (Drosophila) 0.435672
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.434906
IK IK cytokine, down-regulator of HLA II 0.422673
AQP8 aquaporin 8 0.420766
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.419623
HBD hemoglobin, delta 0.415053
MUC3A mucin 3A, cell surface associated 0.411251
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.408592
FGFR4 fibroblast growth factor receptor 4 0.404797
PEX2 peroxisomal biogenesis factor 2 0.398735
MAPK8 mitogen-activated protein kinase 8 0.397979
LACTB lactamase, beta 0.390421
HSF4 heat shock transcription factor 4 0.38552
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.384013
PEX10 peroxisomal biogenesis factor 10 0.382884
GSX1 GS homeobox 1 0.367502
SUB1 SUB1 homolog (S. cerevisiae) 0.363393
TBK1 TANK-binding kinase 1 0.355942
HIST1H1D histone cluster 1, H1d 0.352227
NTS neurotensin 0.348148
MCM5 minichromosome maintenance complex component 5 0.335968
CLPS colipase, pancreatic 0.333028
APOE apolipoprotein E 0.330827
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.328628
ZNF347 zinc finger protein 347 0.32753
PNP purine nucleoside phosphorylase 0.327164
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 0.326432
PYY peptide YY 0.322414
BAG6 BCL2-associated athanogene 6 0.317315
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.316588
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.314046
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.312595
F2 coagulation factor II (thrombin) 0.309335
GAST gastrin 0.306805
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.306444
HBB hemoglobin, beta 0.30464
KRAS Kirsten rat sarcoma viral oncogene homolog 0.298883
MUC6 mucin 6, oligomeric mucus/gel-forming 0.297806
AQP6 aquaporin 6, kidney specific 0.297447
PPARA peroxisome proliferator-activated receptor alpha 0.295297
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.292436
GGT2 gamma-glutamyltransferase 2 0.291008
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.287803
LAP3 leucine aminopeptidase 3 0.287447
RPL5 ribosomal protein L5 0.285316
CYTIP cytohesin 1 interacting protein 0.282837
CEL carboxyl ester lipase 0.2779
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.274045
AFP alpha-fetoprotein 0.270214
GLP2R glucagon-like peptide 2 receptor 0.268482
G6PC glucose-6-phosphatase, catalytic subunit 0.265725
FECH ferrochelatase 0.262986
FOXO1 forkhead box O1 0.260606
B3GAT2 beta-1,3-glucuronyltransferase 2 0.256902
CPOX coproporphyrinogen oxidase 0.255234
EGFR epidermal growth factor receptor 0.252919
CAT catalase 0.24804
ACP2 acid phosphatase 2, lysosomal 0.241132
PI3 peptidase inhibitor 3, skin-derived 0.238706
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.236627
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.234878
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.234878
PTRF polymerase I and transcript release factor 0.232599
FGF1 fibroblast growth factor 1 (acidic) 0.226926
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.226411
TNF tumor necrosis factor 0.2259
MFN1 mitofusin 1 0.224893
ZC3H12D zinc finger CCCH-type containing 12D 0.223906
SORD sorbitol dehydrogenase 0.22246
EPHA1 EPH receptor A1 0.222224
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.222224
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.221061
ACAA1 acetyl-CoA acyltransferase 1 0.219928
TTR transthyretin 0.219264
HIST1H1B histone cluster 1, H1b 0.217762
S100A2 S100 calcium binding protein A2 0.215341
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.214202
FBP1 fructose-1,6-bisphosphatase 1 0.214017
CBR1 carbonyl reductase 1 0.212586