bilirubin Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A member of the class of biladienes that is a linear tetrapyrrole, product of heme degradation. It is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. (Chemical Entities of Biological Interest Ontology, CHEBI_16990)
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Genes

28 genes associated with the disease bilirubin in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
BLVRA biliverdin reductase A
BTBD16 BTB (POZ) domain containing 16
CAMK4 calcium/calmodulin-dependent protein kinase IV
CDH8 cadherin 8, type 2
ERCC4 excision repair cross-complementation group 4
FMNL2 formin-like 2
FREM2 FRAS1 related extracellular matrix protein 2
HMOX1 heme oxygenase 1
KLHL1 kelch-like family member 1
MROH2A maestro heat-like repeat family member 2A
RUNX1 runt-related transcription factor 1
SLC22A18 solute carrier family 22, member 18
SLCO1B1 solute carrier organic anion transporter family, member 1B1
TDRP testis development related protein
TKTL1 transketolase-like 1
TRIM44 tripartite motif containing 44
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
USP40 ubiquitin specific peptidase 40