binding of sperm to zona pellucida Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place. (Gene Ontology, GO_0007339)
External Link http://amigo.geneontology.org/amigo/term/GO:0007339
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Genes

21 genes participating in the binding of sperm to zona pellucida biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM18 ADAM metallopeptidase domain 18
ADAM2 ADAM metallopeptidase domain 2
ADAM32 ADAM metallopeptidase domain 32
CRISP1 cysteine-rich secretory protein 1
FETUB fetuin B
LOC112694756 uncharaterized LOC112694756
LY6K lymphocyte antigen 6 complex, locus K
PCSK4 proprotein convertase subtilisin/kexin type 4
PRSS37 protease, serine, 37
PRSS55 protease, serine, 55
SPACA4 sperm acrosome associated 4
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
TEX101 testis expressed 101
UBAP2L ubiquitin associated protein 2-like
VDAC2 voltage-dependent anion channel 2
ZAN zonadhesin (gene/pseudogene)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4
ZPBP zona pellucida binding protein
ZPBP2 zona pellucida binding protein 2