biotin-2428 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the biotin-2428 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACSF2 acyl-CoA synthetase family member 2
ADCY9 adenylate cyclase 9
AIF1 allograft inflammatory factor 1
AIM1L absent in melanoma 1-like
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
BEGAIN brain-enriched guanylate kinase-associated
C1ORF105 chromosome 1 open reading frame 105
CA5B carbonic anhydrase VB, mitochondrial
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC85C coiled-coil domain containing 85C
CD84 CD84 molecule
CDC25C cell division cycle 25C
CTRL chymotrypsin-like
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DUSP13 dual specificity phosphatase 13
E2F5 E2F transcription factor 5, p130-binding
EFNA3 ephrin-A3
EIF1 eukaryotic translation initiation factor 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM105A family with sequence similarity 105, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLII flightless I homolog (Drosophila)
FSHB follicle stimulating hormone, beta polypeptide
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
H2AFX H2A histone family, member X
ICAM2 intercellular adhesion molecule 2
IDS iduronate 2-sulfatase
IFITM1 interferon induced transmembrane protein 1
IFT27 intraflagellar transport 27
IL12RB1 interleukin 12 receptor, beta 1
INPP5J inositol polyphosphate-5-phosphatase J
IPP intracisternal A particle-promoted polypeptide
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LOC730101 uncharacterized LOC730101
LOX lysyl oxidase
LTB4R leukotriene B4 receptor
LTBP2 latent transforming growth factor beta binding protein 2
MAOA monoamine oxidase A
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAX MYC associated factor X
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MLXIP MLX interacting protein
MLXIPL MLX interacting protein-like
MMP25 matrix metallopeptidase 25
MTAP methylthioadenosine phosphorylase
MYH14 myosin, heavy chain 14, non-muscle
NF2 neurofibromin 2 (merlin)
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OCRL oculocerebrorenal syndrome of Lowe
OMD osteomodulin
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PRAMEF11 PRAME family member 11
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB35 RAB35, member RAS oncogene family
RAD54B RAD54 homolog B (S. cerevisiae)
RND1 Rho family GTPase 1
RPS28 ribosomal protein S28
SAFB scaffold attachment factor B
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SMAD5 SMAD family member 5
SUGP1 SURP and G patch domain containing 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D2 TBC1 domain family, member 2
TBX10 T-box 10
TGFBR3 transforming growth factor, beta receptor III
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM63A transmembrane protein 63A
TP53I11 tumor protein p53 inducible protein 11
TRGV5 T cell receptor gamma variable 5
TRIM62 tripartite motif containing 62
USP29 ubiquitin specific peptidase 29
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
YLPM1 YLP motif containing 1
ZBTB17 zinc finger and BTB domain containing 17
ZNF492 zinc finger protein 492
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADORA3 adenosine A3 receptor
AMH anti-Mullerian hormone
ATXN2 ataxin 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
CD79A CD79a molecule, immunoglobulin-associated alpha
CDA cytidine deaminase
CENPT centromere protein T
CHMP1A charged multivesicular body protein 1A
CKB creatine kinase, brain
CNPY4 canopy FGF signaling regulator 4
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DSPP dentin sialophosphoprotein
DTX4 deltex 4, E3 ubiquitin ligase
EGR2 early growth response 2
EPHB6 EPH receptor B6
FAM127B family with sequence similarity 127, member B
FGF23 fibroblast growth factor 23
FUZ fuzzy planar cell polarity protein
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPALPP1 GPALPP motifs containing 1
GPX2 glutathione peroxidase 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HP haptoglobin
IL2 interleukin 2
IL3RA interleukin 3 receptor, alpha (low affinity)
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL21 kelch-like family member 21
KLHL28 kelch-like family member 28
KLHL36 kelch-like family member 36
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LINS lines homolog (Drosophila)
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
MBTD1 mbt domain containing 1
MILR1 mast cell immunoglobulin-like receptor 1
MIR22HG MIR22 host gene
MTERF1 mitochondrial transcription termination factor 1
MYL5 myosin, light chain 5, regulatory
NIPAL2 NIPA-like domain containing 2
OCEL1 occludin/ELL domain containing 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PDLIM2 PDZ and LIM domain 2 (mystique)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITX2 paired-like homeodomain 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PROCR protein C receptor, endothelial
PTGES2 prostaglandin E synthase 2
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOF ras homolog family member F (in filopodia)
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNX15 sorting nexin 15
SPATS2 spermatogenesis associated, serine-rich 2
SSFA2 sperm specific antigen 2
STK16 serine/threonine kinase 16
TAGLN transgelin
TBC1D19 TBC1 domain family, member 19
TCEA2 transcription elongation factor A (SII), 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TLN1 talin 1
TMEM184C transmembrane protein 184C
TRABD TraB domain containing
TRAF1 TNF receptor-associated factor 1
TRDMT1 tRNA aspartic acid methyltransferase 1
TTC30A tetratricopeptide repeat domain 30A
TTLL1 tubulin tyrosine ligase-like family member 1
UPP1 uridine phosphorylase 1
VEGFC vascular endothelial growth factor C
WDR33 WD repeat domain 33
WNT16 wingless-type MMTV integration site family, member 16
ZNF215 zinc finger protein 215
ZNF701 zinc finger protein 701
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862