biotin-3289 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the biotin-3289 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACRV1 acrosomal vesicle protein 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOE apolipoprotein E
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BHLHE40 basic helix-loop-helix family, member e40
C19ORF73 chromosome 19 open reading frame 73
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNK cyclin K
CD1A CD1a molecule
CD58 CD58 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CFHR4 complement factor H-related 4
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN4 chloride channel, voltage-sensitive 4
CLCN6 chloride channel, voltage-sensitive 6
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYTH1 cytohesin 1
DFNB31 deafness, autosomal recessive 31
DMBT1 deleted in malignant brain tumors 1
DNASE1 deoxyribonuclease I
DSC2 desmocollin 2
EGR1 early growth response 1
ELAC2 elaC ribonuclease Z 2
ELSPBP1 epididymal sperm binding protein 1
EMX1 empty spiracles homeobox 1
EPX eosinophil peroxidase
F11 coagulation factor XI
FGF23 fibroblast growth factor 23
FLJ11292
FLT3 fms-related tyrosine kinase 3
FZD9 frizzled class receptor 9
GPC1 glypican 1
GPR3 G protein-coupled receptor 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL22 interleukin 22
INA internexin neuronal intermediate filament protein, alpha
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT17 keratin 17, type I
LONP2 lon peptidase 2, peroxisomal
MCAM melanoma cell adhesion molecule
MED20 mediator complex subunit 20
MGC2889 uncharacterized protein MGC2889
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIA melanoma inhibitory activity
MMRN2 multimerin 2
MYOZ1 myozenin 1
MZF1 myeloid zinc finger 1
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NNAT neuronatin
NRL neural retina leucine zipper
NT5M 5',3'-nucleotidase, mitochondrial
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OGFR opioid growth factor receptor
PCDHGA10 protocadherin gamma subfamily A, 10
PDE12 phosphodiesterase 12
PDZK1IP1 PDZK1 interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POLL polymerase (DNA directed), lambda
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCI protein kinase C, iota
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RHEB Ras homolog enriched in brain
RNF126P1 ring finger protein 126 pseudogene 1
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERHL2 serine hydrolase-like 2
SFRP5 secreted frizzled-related protein 5
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SKI SKI proto-oncogene
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPHK2 sphingosine kinase 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBXA2R thromboxane A2 receptor
TMC5 transmembrane channel-like 5
TNS1 tensin 1
TNXB tenascin XB
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSNAXIP1 translin-associated factor X interacting protein 1
UPK3B uroplakin 3B
VARS valyl-tRNA synthetase
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
ZNF154 zinc finger protein 154
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ATP13A2 ATPase type 13A2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C4ORF29 chromosome 4 open reading frame 29
C5AR2 complement component 5a receptor 2
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN15 calpain 15
CD151 CD151 molecule (Raph blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CLGN calmegin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DGAT1 diacylglycerol O-acyltransferase 1
DUSP2 dual specificity phosphatase 2
EFHD2 EF-hand domain family, member D2
FAM86C1 family with sequence similarity 86, member C1
FBXL15 F-box and leucine-rich repeat protein 15
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GSTCD glutathione S-transferase, C-terminal domain containing
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AE histone cluster 1, H2ae
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL12RB1 interleukin 12 receptor, beta 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0754 KIAA0754
KLF11 Kruppel-like factor 11
KRT13 keratin 13, type I
LARP6 La ribonucleoprotein domain family, member 6
LRRC20 leucine rich repeat containing 20
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MGC12488
MTCP1 mature T-cell proliferation 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MXD3 MAX dimerization protein 3
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NRTN neurturin
OGFRL1 opioid growth factor receptor-like 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI2 peptidyl arginine deiminase, type II
PARD6B par-6 family cell polarity regulator beta
PCDHB3 protocadherin beta 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PNPLA6 patatin-like phospholipase domain containing 6
POMT2 protein-O-mannosyltransferase 2
PROS1 protein S (alpha)
PTDSS2 phosphatidylserine synthase 2
RAB5B RAB5B, member RAS oncogene family
RIN2 Ras and Rab interactor 2
RNF43 ring finger protein 43
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS14P3 ribosomal protein S14 pseudogene 3
S100A4 S100 calcium binding protein A4
SECTM1 secreted and transmembrane 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT6 sirtuin 6
SLC12A8 solute carrier family 12, member 8
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNHG20 small nucleolar RNA host gene 20
STK25 serine/threonine kinase 25
STXBP2 syntaxin binding protein 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM8 tripartite motif containing 8
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
WLS wntless Wnt ligand secretion mediator
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF219 zinc finger protein 219
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF552 zinc finger protein 552
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701
ZNF721 zinc finger protein 721
ZNHIT2 zinc finger, HIT-type containing 2