biotin-6689 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the biotin-6689 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
AIF1 allograft inflammatory factor 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ATF6B activating transcription factor 6 beta
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARTPT CART prepropeptide
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC25C cell division cycle 25C
CEP152 centrosomal protein 152kDa
CISH cytokine inducible SH2-containing protein
CLCN4 chloride channel, voltage-sensitive 4
COL9A2 collagen, type IX, alpha 2
CREBZF CREB/ATF bZIP transcription factor
CTNS cystinosin, lysosomal cystine transporter
DAPK2 death-associated protein kinase 2
DOCK9 dedicator of cytokinesis 9
DSCAM Down syndrome cell adhesion molecule
DZIP1 DAZ interacting zinc finger protein 1
EDN3 endothelin 3
EMC1 ER membrane protein complex subunit 1
ETV6 ets variant 6
ETV7 ets variant 7
F5 coagulation factor V (proaccelerin, labile factor)
GLP1R glucagon-like peptide 1 receptor
GRM8 glutamate receptor, metabotropic 8
GUSBP3 glucuronidase, beta pseudogene 3
H2AFX H2A histone family, member X
HAPLN1 hyaluronan and proteoglycan link protein 1
HIC2 hypermethylated in cancer 2
HIPK3 homeodomain interacting protein kinase 3
HPS1 Hermansky-Pudlak syndrome 1
HYAL1 hyaluronoglucosaminidase 1
IL36G interleukin 36, gamma
JPH3 junctophilin 3
JUND jun D proto-oncogene
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLK10 kallikrein-related peptidase 10
LARP7 La ribonucleoprotein domain family, member 7
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBNL2 muscleblind-like splicing regulator 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPIPB3 nuclear pore complex interacting protein family, member B3
NTS neurotensin
NUP54 nucleoporin 54kDa
OLFM1 olfactomedin 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OVOL2 ovo-like zinc finger 2
PDIA2 protein disulfide isomerase family A, member 2
PHOX2B paired-like homeobox 2b
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNB3 plexin B3
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PVR poliovirus receptor
PXN paxillin
RARG retinoic acid receptor, gamma
RECQL5 RecQ protein-like 5
RHOT2 ras homolog family member T2
RPS3A ribosomal protein S3A
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOCS3 suppressor of cytokine signaling 3
SOS2 son of sevenless homolog 2 (Drosophila)
SP1 Sp1 transcription factor
SRSF5 serine/arginine-rich splicing factor 5
TACR1 tachykinin receptor 1
TBC1D30 TBC1 domain family, member 30
TEF thyrotrophic embryonic factor
TMPRSS2 transmembrane protease, serine 2
TPM3 tropomyosin 3
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM3 tripartite motif containing 3
TROVE2 TROVE domain family, member 2
TSPAN1 tetraspanin 1
TSPAN9 tetraspanin 9
YTHDC2 YTH domain containing 2
ZER1 zyg-11 related, cell cycle regulator
ZMAT4 zinc finger, matrin-type 4
ZNF24 zinc finger protein 24
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AGMAT agmatine ureohydrolase (agmatinase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARMCX4 armadillo repeat containing, X-linked 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG4 BCL2-associated athanogene 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
C16ORF45 chromosome 16 open reading frame 45
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC106 coiled-coil domain containing 106
CCDC186 coiled-coil domain containing 186
CD68 CD68 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKL3 cyclin-dependent kinase-like 3
CGA glycoprotein hormones, alpha polypeptide
CHRDL1 chordin-like 1
CYB5R2 cytochrome b5 reductase 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DPF3 D4, zinc and double PHD fingers, family 3
EPHA4 EPH receptor A4
FBXL15 F-box and leucine-rich repeat protein 15
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP10 FK506 binding protein 10, 65 kDa
GALK1 galactokinase 1
GALT galactose-1-phosphate uridylyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H3B histone cluster 1, H3b
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA6 homeobox A6
HOXC13 homeobox C13
HOXC5 homeobox C5
IER3IP1 immediate early response 3 interacting protein 1
IFT54 intraflagellar transport 54
INPPL1 inositol polyphosphate phosphatase-like 1
IQSEC2 IQ motif and Sec7 domain 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
LIME1 Lck interacting transmembrane adaptor 1
LINC00341 long intergenic non-protein coding RNA 341
LOC100287590 uncharacterized LOC100287590
LOC257152 uncharacterized LOC257152
LPAR4 lysophosphatidic acid receptor 4
LRRC6 leucine rich repeat containing 6
MGP matrix Gla protein
MMP13 matrix metallopeptidase 13
MRPL41 mitochondrial ribosomal protein L41
MRPL44 mitochondrial ribosomal protein L44
MYH15 myosin, heavy chain 15
NAG18 NAG18 mRNA
NAT6 N-acetyltransferase 6 (GCN5-related)
NLGN1 neuroligin 1
NPM3 nucleophosmin/nucleoplasmin 3
NXPH4 neurexophilin 4
OLFML2A olfactomedin-like 2A
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRR7 proline rich 7 (synaptic)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAG2 recombination activating gene 2
RAI2 retinoic acid induced 2
RIBC2 RIB43A domain with coiled-coils 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROM1 retinal outer segment membrane protein 1
SCAMP5 secretory carrier membrane protein 5
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECISBP2 SECIS binding protein 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A8 solute carrier family 12, member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TESK1 testis-specific kinase 1
TFF2 trefoil factor 2
TIAM2 T-cell lymphoma invasion and metastasis 2
TK2 thymidine kinase 2, mitochondrial
TMEM212 transmembrane protein 212
TUBG2 tubulin, gamma 2
WNT7A wingless-type MMTV integration site family, member 7A
ZNF222 zinc finger protein 222
ZNF37BP zinc finger protein 37B, pseudogene
ZNF571 zinc finger protein 571
ZNF623 zinc finger protein 623
ZNF702P zinc finger protein 702, pseudogene
ZNF770 zinc finger protein 770
ZSCAN2 zinc finger and SCAN domain containing 2