biperiden-2460 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the biperiden-2460 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADGRG2 adhesion G protein-coupled receptor G2
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
B9D1 B9 protein domain 1
BEGAIN brain-enriched guanylate kinase-associated
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C5ORF45 chromosome 5 open reading frame 45
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC85C coiled-coil domain containing 85C
CCSER2 coiled-coil serine-rich protein 2
CD248 CD248 molecule, endosialin
CEND1 cell cycle exit and neuronal differentiation 1
CLEC3B C-type lectin domain family 3, member B
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRHR2 corticotropin releasing hormone receptor 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DIO2 deiodinase, iodothyronine, type II
DNMBP dynamin binding protein
EIF1 eukaryotic translation initiation factor 1
EPN1 epsin 1
FBLN1 fibulin 1
FBXO31 F-box protein 31
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOSR2 golgi SNAP receptor complex member 2
GPR132 G protein-coupled receptor 132
GPR137 G protein-coupled receptor 137
GPR176 G protein-coupled receptor 176
HOMER3 homer scaffolding protein 3
HOXB9 homeobox B9
IFT122 intraflagellar transport 122
IFT27 intraflagellar transport 27
IFT54 intraflagellar transport 54
IL1RN interleukin 1 receptor antagonist
IL6R interleukin 6 receptor
IQCK IQ motif containing K
KAT8 K(lysine) acetyltransferase 8
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF1A kinesin family member 1A
KRT8P12 keratin 8 pseudogene 12
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LIG3 ligase III, DNA, ATP-dependent
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTB4R leukotriene B4 receptor
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLXIPL MLX interacting protein-like
MNMIP1 manchette microtubule inner protein 1
MRPS12 mitochondrial ribosomal protein S12
MYBPC3 myosin binding protein C, cardiac
MYL10 myosin, light chain 10, regulatory
NADK NAD kinase
NDRG3 NDRG family member 3
NEK9 NIMA-related kinase 9
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOX1 NADPH oxidase 1
NPC1 Niemann-Pick disease, type C1
NUP188 nucleoporin 188kDa
NUP54 nucleoporin 54kDa
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGB5 protocadherin gamma subfamily B, 5
PEX10 peroxisomal biogenesis factor 10
PLK4 polo-like kinase 4
PPP1R26 protein phosphatase 1, regulatory subunit 26
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40A RAB40A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RHOD ras homolog family member D
RNASE3 ribonuclease, RNase A family, 3
RXRB retinoid X receptor, beta
SEC24D SEC24 family member D
SHB Src homology 2 domain containing adaptor protein B
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPPL2B signal peptide peptidase like 2B
SS18 synovial sarcoma translocation, chromosome 18
SYK spleen tyrosine kinase
SYNC syncoilin, intermediate filament protein
T T, brachyury homolog (mouse)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAT tyrosine aminotransferase
TEC tec protein tyrosine kinase
TPM3 tropomyosin 3
TRD T cell receptor delta locus
TYMP thymidine phosphorylase
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFHX4 zinc finger homeobox 4
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF154 zinc finger protein 154
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
AMH anti-Mullerian hormone
APH1B APH1B gamma secretase subunit
APOLD1 apolipoprotein L domain containing 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CAMTA1 calmodulin binding transcription activator 1
CCDC132 coiled-coil domain containing 132
CD34 CD34 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CNTLN centlein, centrosomal protein
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOK5 docking protein 5
EMID1 EMI domain containing 1
EMILIN2 elastin microfibril interfacer 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM127A family with sequence similarity 127, member A
FAM131A family with sequence similarity 131, member A
FBP1 fructose-1,6-bisphosphatase 1
FCHO1 FCH domain only 1
FGF22 fibroblast growth factor 22
FGL1 fibrinogen-like 1
FKBP9 FK506 binding protein 9, 63 kDa
FMOD fibromodulin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAS6 growth arrest-specific 6
GK2 glycerol kinase 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GOLGA2P5 golgin A2 pseudogene 5
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GRIP2 glutamate receptor interacting protein 2
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA5 homeobox A5
HRH2 histamine receptor H2
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IHH indian hedgehog
IL2 interleukin 2
ITGA10 integrin, alpha 10
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLHL28 kelch-like family member 28
KLHL36 kelch-like family member 36
LAX1 lymphocyte transmembrane adaptor 1
LHFPL2 lipoma HMGIC fusion partner-like 2
LOC257152 uncharacterized LOC257152
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCTP2 multiple C2 domains, transmembrane 2
MIR22HG MIR22 host gene
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCKAP1L NCK-associated protein 1-like
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PADI1 peptidyl arginine deiminase, type I
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP prolactin-induced protein
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
QPCTL glutaminyl-peptide cyclotransferase-like
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RCAN3 RCAN family member 3
REC8 REC8 meiotic recombination protein
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF126P1 ring finger protein 126 pseudogene 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH2D4A SH2 domain containing 4A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAGLN transgelin
TICAM1 toll-like receptor adaptor molecule 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM254 transmembrane protein 254
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D4 TSC22 domain family, member 4
TTC30A tetratricopeptide repeat domain 30A
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
VEGFC vascular endothelial growth factor C
VEZT vezatin, adherens junctions transmembrane protein
VPS9D1 VPS9 domain containing 1
WNT16 wingless-type MMTV integration site family, member 16
ZBTB38 zinc finger and BTB domain containing 38
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF749 zinc finger protein 749