biperiden-3321 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the biperiden-3321 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
ADAM22 ADAM metallopeptidase domain 22
ALOX15 arachidonate 15-lipoxygenase
AMACR alpha-methylacyl-CoA racemase
AMPD3 adenosine monophosphate deaminase 3
ARC activity-regulated cytoskeleton-associated protein
ARPIN actin-related protein 2/3 complex inhibitor
ARR3 arrestin 3, retinal (X-arrestin)
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C1ORF54 chromosome 1 open reading frame 54
CAPN15 calpain 15
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEL carboxyl ester lipase
CLDN1 claudin 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CRTC1 CREB regulated transcription coactivator 1
CTIF CBP80/20-dependent translation initiation factor
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DMXL2 Dmx-like 2
DSC2 desmocollin 2
EPHB2 EPH receptor B2
FGFR1 fibroblast growth factor receptor 1
FSCN1 fascin actin-bundling protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GLB1L galactosidase, beta 1-like
GLS glutaminase
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
GRK5 G protein-coupled receptor kinase 5
GRM1 glutamate receptor, metabotropic 1
GRM7 glutamate receptor, metabotropic 7
HFE hemochromatosis
HNF4A hepatocyte nuclear factor 4, alpha
HR hair growth associated
KCTD17 potassium channel tetramerization domain containing 17
KIF25 kinesin family member 25
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT24 keratin 24, type I
KRT75 keratin 75, type II
KRT83 keratin 83, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAOB monoamine oxidase B
MAP2K5 mitogen-activated protein kinase kinase 5
MARK4 MAP/microtubule affinity-regulating kinase 4
MED18 mediator complex subunit 18
METTL5 methyltransferase like 5
MLANA melan-A
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOF myoferlin
NPR2 natriuretic peptide receptor 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
PCDHB6 protocadherin beta 6
PCDHGA10 protocadherin gamma subfamily A, 10
PLCH1 phospholipase C, eta 1
POLM polymerase (DNA directed), mu
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRLH prolactin releasing hormone
PXN paxillin
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGS12 regulator of G-protein signaling 12
RIN1 Ras and Rab interactor 1
RNFT1 ring finger protein, transmembrane 1
RPL7 ribosomal protein L7
RSU1 Ras suppressor protein 1
SEC24D SEC24 family member D
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SULT4A1 sulfotransferase family 4A, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN2 synapsin II
TGM2 transglutaminase 2
TLDC1 TBC/LysM-associated domain containing 1
TMC6 transmembrane channel-like 6
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
TRA T cell receptor alpha locus
TRAPPC9 trafficking protein particle complex 9
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
VN1R1 vomeronasal 1 receptor 1
VSIG4 V-set and immunoglobulin domain containing 4
WDR76 WD repeat domain 76
WDTC1 WD and tetratricopeptide repeats 1
WIZ widely interspaced zinc finger motifs
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
AFAP1 actin filament associated protein 1
AHNAK2 AHNAK nucleoprotein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BGLAP bone gamma-carboxyglutamate (gla) protein
C21ORF91 chromosome 21 open reading frame 91
C5AR2 complement component 5a receptor 2
C8ORF44 chromosome 8 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPO centromere protein O
CERS4 ceramide synthase 4
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CLEC4E C-type lectin domain family 4, member E
CTRL chymotrypsin-like
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EPHX2 epoxide hydrolase 2, cytoplasmic
FADS2 fatty acid desaturase 2
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPR guanosine monophosphate reductase
GPATCH3 G patch domain containing 3
H1F0 H1 histone family, member 0
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCTD7 potassium channel tetramerization domain containing 7
KDM7A lysine (K)-specific demethylase 7A
KIF20A kinesin family member 20A
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00339 long intergenic non-protein coding RNA 339
LMAN1 lectin, mannose-binding, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
METTL16 methyltransferase like 16
METTL4 methyltransferase like 4
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MOCS3 molybdenum cofactor synthesis 3
MRPL44 mitochondrial ribosomal protein L44
NCALD neurocalcin delta
NPM3 nucleophosmin/nucleoplasmin 3
NSUN6 NOP2/Sun domain family, member 6
NT5DC3 5'-nucleotidase domain containing 3
OLFML2A olfactomedin-like 2A
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFTN1 raftlin, lipid raft linker 1
RLN1 relaxin 1
RNF121 ring finger protein 121
RPL10L ribosomal protein L10-like
SAYSD1 SAYSVFN motif domain containing 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLPI secretory leukocyte peptidase inhibitor
SOX12 SRY (sex determining region Y)-box 12
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TLR2 toll-like receptor 2
TMCC2 transmembrane and coiled-coil domain family 2
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
VIPR1 vasoactive intestinal peptide receptor 1
WFDC2 WAP four-disulfide core domain 2
YY2 YY2 transcription factor
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF204P zinc finger protein 204, pseudogene
ZNF33B zinc finger protein 33B
ZNF365 zinc finger protein 365
ZNF532 zinc finger protein 532
ZNF747 zinc finger protein 747