biperiden-5279 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the biperiden-5279 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
ALOX5 arachidonate 5-lipoxygenase
AMACR alpha-methylacyl-CoA racemase
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARNT aryl hydrocarbon receptor nuclear translocator
ASIC1 acid sensing (proton gated) ion channel 1
ATG10 autophagy related 10
BTN3A1 butyrophilin, subfamily 3, member A1
C3 complement component 3
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CD3D CD3d molecule, delta (CD3-TCR complex)
CD83 CD83 molecule
CDHR2 cadherin-related family member 2
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFAP70 cilia and flagella associated protein 70
COL19A1 collagen, type XIX, alpha 1
COL5A2 collagen, type V, alpha 2
COPA coatomer protein complex, subunit alpha
CSF1 colony stimulating factor 1 (macrophage)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DIO2 deiodinase, iodothyronine, type II
DLX2 distal-less homeobox 2
DMP1 dentin matrix acidic phosphoprotein 1
DMXL2 Dmx-like 2
DOCK6 dedicator of cytokinesis 6
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DVL2 dishevelled segment polarity protein 2
FOXG1 forkhead box G1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GOLGA8A golgin A8 family, member A
GP2 glycoprotein 2 (zymogen granule membrane)
GPR137 G protein-coupled receptor 137
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDLBP high density lipoprotein binding protein
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IFT54 intraflagellar transport 54
IL18 interleukin 18
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIF1C kinesin family member 1C
KRT75 keratin 75, type II
KRT8 keratin 8, type II
LIF leukemia inhibitory factor
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEF2D myocyte enhancer factor 2D
MFAP3L microfibrillar-associated protein 3-like
MMP11 matrix metallopeptidase 11
MTAP methylthioadenosine phosphorylase
MYB v-myb avian myeloblastosis viral oncogene homolog
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NTNG1 netrin G1
OGFR opioid growth factor receptor
OLFML2A olfactomedin-like 2A
PAX8 paired box 8
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM7 PDZ and LIM domain 7 (enigma)
PGAM2 phosphoglycerate mutase 2 (muscle)
PIAS2 protein inhibitor of activated STAT, 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT2 protein arginine methyltransferase 2
PRUNE2 prune homolog 2 (Drosophila)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAPSN receptor-associated protein of the synapse
SDC3 syndecan 3
SIRT5 sirtuin 5
SLC39A9 solute carrier family 39, member 9
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD1 SMAD family member 1
SSX1 synovial sarcoma, X breakpoint 1
STK24 serine/threonine kinase 24
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SVIL supervillin
SYT5 synaptotagmin V
TBC1D22A TBC1 domain family, member 22A
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGM4 transglutaminase 4
TRIO trio Rho guanine nucleotide exchange factor
UBXN1 UBX domain protein 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZNF345 zinc finger protein 345
ZNF440 zinc finger protein 440
ZNF446 zinc finger protein 446
ZNF518A zinc finger protein 518A
ZNF551 zinc finger protein 551
ZNF76 zinc finger protein 76
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
ADTRP androgen-dependent TFPI-regulating protein
AMPD1 adenosine monophosphate deaminase 1
ARL15 ADP-ribosylation factor-like 15
BCAS1 breast carcinoma amplified sequence 1
BLNK B-cell linker
BMP10 bone morphogenetic protein 10
C1ORF21 chromosome 1 open reading frame 21
CD82 CD82 molecule
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CIDEC cell death-inducing DFFA-like effector c
CLDN1 claudin 1
CNTN1 contactin 1
CPA4 carboxypeptidase A4
CRABP1 cellular retinoic acid binding protein 1
CUL9 cullin 9
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNM3 dynamin 3
ECHDC3 enoyl CoA hydratase domain containing 3
EDAR ectodysplasin A receptor
FADS2 fatty acid desaturase 2
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
FRMD1 FERM domain containing 1
GAS2 growth arrest-specific 2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR27 G protein-coupled receptor 27
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H4E histone cluster 1, H4e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IL2RG interleukin 2 receptor, gamma
INPP1 inositol polyphosphate-1-phosphatase
KIF5A kinesin family member 5A
KLHL25 kelch-like family member 25
LAX1 lymphocyte transmembrane adaptor 1
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYL5 myosin, light chain 5, regulatory
MYOZ3 myozenin 3
NEUROD4 neuronal differentiation 4
NPM3 nucleophosmin/nucleoplasmin 3
OCA2 oculocutaneous albinism II
ONECUT2 one cut homeobox 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
OVOL1 ovo-like zinc finger 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDHB13 protocadherin beta 13
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PENK proenkephalin
PLAC1 placenta-specific 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POU4F2 POU class 4 homeobox 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPL10L ribosomal protein L10-like
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SDS serine dehydratase
SEPP1 selenoprotein P, plasma, 1
SETD1A SET domain containing 1A
SIGLEC15 sialic acid binding Ig-like lectin 15
STRA6 stimulated by retinoic acid 6
TESK1 testis-specific kinase 1
TEX14 testis expressed 14
TEX40 testis expressed 40
TGFBR1 transforming growth factor, beta receptor 1
TMEM212 transmembrane protein 212
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TUBA3D tubulin, alpha 3d
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
XYLT1 xylosyltransferase I
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZNF747 zinc finger protein 747
ZSCAN26 zinc finger and SCAN domain containing 26