biperiden-5644 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the biperiden-5644 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ADARB1 adenosine deaminase, RNA-specific, B1
AKR1C1 aldo-keto reductase family 1, member C1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
CA4 carbonic anhydrase IV
CADM4 cell adhesion molecule 4
CAMKV CaM kinase-like vesicle-associated
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK13 cyclin-dependent kinase 13
CEP295 centrosomal protein 295kDa
CHKB choline kinase beta
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
COL13A1 collagen, type XIII, alpha 1
COL17A1 collagen, type XVII, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREM cAMP responsive element modulator
CTIF CBP80/20-dependent translation initiation factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DLC1 DLC1 Rho GTPase activating protein
DZIP3 DAZ interacting zinc finger protein 3
EDA ectodysplasin A
EDNRA endothelin receptor type A
FBXO21 F-box protein 21
FGF13 fibroblast growth factor 13
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT3LG fms-related tyrosine kinase 3 ligand
FOXI1 forkhead box I1
HEG1 heart development protein with EGF-like domains 1
HFE hemochromatosis
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXA11 homeobox A11
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
ITGB8 integrin, beta 8
KIF13A kinesin family member 13A
KRT75 keratin 75, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP1 lysosomal-associated membrane protein 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAOB monoamine oxidase B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MID1 midline 1
MKL1 megakaryoblastic leukemia (translocation) 1
MMP11 matrix metallopeptidase 11
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVB12B multivesicular body subunit 12B
MYBPC3 myosin binding protein C, cardiac
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PALM paralemmin
PBX2 pre-B-cell leukemia homeobox 2
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK3 polo-like kinase 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRKCB protein kinase C, beta
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RBM34 RNA binding motif protein 34
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RSL1D1 ribosomal L1 domain containing 1
RUNDC3A RUN domain containing 3A
SC5D sterol-C5-desaturase
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH3GL3 SH3-domain GRB2-like 3
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35E2 solute carrier family 35, member E2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMR3A submaxillary gland androgen regulated protein 3A
SPON1 spondin 1, extracellular matrix protein
SSX1 synovial sarcoma, X breakpoint 1
TEX14 testis expressed 14
TPMT thiopurine S-methyltransferase
TSC22D2 TSC22 domain family, member 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPRBP Vpr (HIV-1) binding protein
VSNL1 visinin-like 1
WAPAL wings apart-like homolog (Drosophila)
ZEB1 zinc finger E-box binding homeobox 1
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF277 zinc finger protein 277
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADCY7 adenylate cyclase 7
AHNAK2 AHNAK nucleoprotein 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AQP7 aquaporin 7
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIR1 corepressor interacting with RBPJ, 1
CNTN1 contactin 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPED1 cadherin-like and PC-esterase domain containing 1
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOK5 docking protein 5
DYSF dysferlin
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPX eosinophil peroxidase
EXOC6B exocyst complex component 6B
EXOSC1 exosome component 1
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FRMD1 FERM domain containing 1
GAS2 growth arrest-specific 2
GEM GTP binding protein overexpressed in skeletal muscle
GFI1 growth factor independent 1 transcription repressor
GK2 glycerol kinase 2
GPR1 G protein-coupled receptor 1
GPR27 G protein-coupled receptor 27
GPR39 G protein-coupled receptor 39
HCG4 HLA complex group 4 (non-protein coding)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H3E histone cluster 1, H3e
HIST1H4D histone cluster 1, H4d
HP haptoglobin
HPN hepsin
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL2 interleukin 2
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK10 potassium channel, two pore domain subfamily K, member 10
LRP5L low density lipoprotein receptor-related protein 5-like
MAK male germ cell-associated kinase
MXRA8 matrix-remodelling associated 8
NCALD neurocalcin delta
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX9 paired box 9
PCDHA5 protocadherin alpha 5
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
PQLC2 PQ loop repeat containing 2
PRAMEF10 PRAME family member 10
PRAMEF11 PRAME family member 11
PRB3 proline-rich protein BstNI subfamily 3
PRDM16 PR domain containing 16
PROL1 proline rich, lacrimal 1
PRSS53 protease, serine, 53
PSG11 pregnancy specific beta-1-glycoprotein 11
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SAG S-antigen; retina and pineal gland (arrestin)
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SP1 Sp1 transcription factor
SPRR1B small proline-rich protein 1B
SSTR4 somatostatin receptor 4
STRA6 stimulated by retinoic acid 6
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TUBA4B tubulin, alpha 4b
TUBB7P tubulin, beta 7, pseudogene
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
VN1R1 vomeronasal 1 receptor 1
VNN2 vanin 2
WNT10B wingless-type MMTV integration site family, member 10B
YY2 YY2 transcription factor
ZFHX4 zinc finger homeobox 4
ZNF205 zinc finger protein 205
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816