| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the bisacodyl-4616 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIF1 | allograft inflammatory factor 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| ATF3 | activating transcription factor 3 |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CA4 | carbonic anhydrase IV |
| CCDC85C | coiled-coil domain containing 85C |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDH8 | cadherin 8, type 2 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CMA1 | chymase 1, mast cell |
| COL3A1 | collagen, type III, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CRYBB1 | crystallin, beta B1 |
| CSN2 | casein beta |
| CTSE | cathepsin E |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DRP2 | dystrophin related protein 2 |
| DSC1 | desmocollin 1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHA7 | EPH receptor A7 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FGF18 | fibroblast growth factor 18 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) |
| GRM4 | glutamate receptor, metabotropic 4 |
| GTPBP1 | GTP binding protein 1 |
| IGHM | immunoglobulin heavy constant mu |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IHH | indian hedgehog |
| IL11 | interleukin 11 |
| IL6 | interleukin 6 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KLHL25 | kelch-like family member 25 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MFAP5 | microfibrillar associated protein 5 |
| MORN1 | MORN repeat containing 1 |
| MSR1 | macrophage scavenger receptor 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NCLN | nicalin |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NEUROG1 | neurogenin 1 |
| NF1 | neurofibromin 1 |
| OTOF | otoferlin |
| PADI4 | peptidyl arginine deiminase, type IV |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RBP3 | retinol binding protein 3, interstitial |
| RGS12 | regulator of G-protein signaling 12 |
| RS1 | retinoschisin 1 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLA | Src-like-adaptor |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STC2 | stanniocalcin 2 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SYT5 | synaptotagmin V |
| TGFB2 | transforming growth factor, beta 2 |
| THPO | thrombopoietin |
| TMEM19 | transmembrane protein 19 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRD | T cell receptor delta locus |
| TSSK2 | testis-specific serine kinase 2 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VGF | VGF nerve growth factor inducible |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CBR3 | carbonyl reductase 3 |
| CCNA1 | cyclin A1 |
| CEP70 | centrosomal protein 70kDa |
| CHEK2 | checkpoint kinase 2 |
| CHMP7 | charged multivesicular body protein 7 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPA4 | carboxypeptidase A4 |
| CTSO | cathepsin O |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOLK | dolichol kinase |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FAM50B | family with sequence similarity 50, member B |
| FZD3 | frizzled class receptor 3 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| IRF1 | interferon regulatory factor 1 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0753 | KIAA0753 |
| KIAA1462 | KIAA1462 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LMNB1 | lamin B1 |
| LOC100272216 | uncharacterized LOC100272216 |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MUTYH | mutY homolog |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NHLRC2 | NHL repeat containing 2 |
| NLRX1 | NLR family member X1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRR15L | proline rich 15-like |
| PRR7 | proline rich 7 (synaptic) |
| PTK6 | protein tyrosine kinase 6 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RANBP17 | RAN binding protein 17 |
| RINT1 | RAD50 interactor 1 |
| SALL2 | spalt-like transcription factor 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2D4A | SH2 domain containing 4A |
| SHROOM2 | shroom family member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAC | SH3 and cysteine rich domain |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TGDS | TDP-glucose 4,6-dehydratase |
| TGS1 | trimethylguanosine synthase 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM177 | transmembrane protein 177 |
| TRIM68 | tripartite motif containing 68 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| UNC119 | unc-119 homolog (C. elegans) |
| YY2 | YY2 transcription factor |
| ZNF177 | zinc finger protein 177 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF239 | zinc finger protein 239 |
| ZNF274 | zinc finger protein 274 |
| ZNF276 | zinc finger protein 276 |
| ZNF365 | zinc finger protein 365 |
| ZNF629 | zinc finger protein 629 |
| ZNF696 | zinc finger protein 696 |
| ZNF7 | zinc finger protein 7 |
| ZNF839 | zinc finger protein 839 |
| ZXDC | ZXD family zinc finger C |