bisoprolol-1287 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bisoprolol-1287 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARL1 ADP-ribosylation factor-like 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A3 ATPase type 13A3
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C6ORF62 chromosome 6 open reading frame 62
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC93 coiled-coil domain containing 93
CCNG2 cyclin G2
CD52 CD52 molecule
CDC5L cell division cycle 5-like
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK10 cyclin-dependent kinase 10
CDK6 cyclin-dependent kinase 6
CLCF1 cardiotrophin-like cytokine factor 1
CLIC4 chloride intracellular channel 4
COPA coatomer protein complex, subunit alpha
CTIF CBP80/20-dependent translation initiation factor
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DOK5 docking protein 5
ELL2 elongation factor, RNA polymerase II, 2
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERLIN1 ER lipid raft associated 1
FEM1C fem-1 homolog c (C. elegans)
FNTB farnesyltransferase, CAAX box, beta
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMD1 FERM domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR19 G protein-coupled receptor 19
GTF2I general transcription factor IIi
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HBS1L HBS1-like translational GTPase
HCRP1 hepatocellular carcinoma-related HCRP1
HIC2 hypermethylated in cancer 2
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL3RA interleukin 3 receptor, alpha (low affinity)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCTD13 potassium channel tetramerization domain containing 13
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK5 kallikrein-related peptidase 5
LINC00094 long intergenic non-protein coding RNA 94
LMAN1 lectin, mannose-binding, 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAOA monoamine oxidase A
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MED20 mediator complex subunit 20
MED21 mediator complex subunit 21
METTL5 methyltransferase like 5
MKL2 MKL/myocardin-like 2
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO1E myosin IE
NFYA nuclear transcription factor Y, alpha
NRP1 neuropilin 1
NXT2 nuclear transport factor 2-like export factor 2
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PDZD7 PDZ domain containing 7
PHTF2 putative homeodomain transcription factor 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAGL2 pleiomorphic adenoma gene-like 2
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PPARD peroxisome proliferator-activated receptor delta
PRNP prion protein
RAB6A RAB6A, member RAS oncogene family
RASA3 RAS p21 protein activator 3
RFXAP regulatory factor X-associated protein
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RPS2 ribosomal protein S2
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP1B ribosomal RNA processing 1B
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIRT5 sirtuin 5
SLC25A40 solute carrier family 25, member 40
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SP1 Sp1 transcription factor
SRPR signal recognition particle receptor (docking protein)
SRSF1 serine/arginine-rich splicing factor 1
SSBP3 single stranded DNA binding protein 3
TMCO1 transmembrane and coiled-coil domains 1
TMEM134 transmembrane protein 134
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF552 zinc finger protein 552
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD14A abhydrolase domain containing 14A
AIM2 absent in melanoma 2
ANAPC2 anaphase promoting complex subunit 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APH1A APH1A gamma secretase subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCORL1 BCL6 corepressor-like 1
BLVRB biliverdin reductase B
C1ORF21 chromosome 1 open reading frame 21
CA5BP1 carbonic anhydrase VB pseudogene 1
CENPJ centromere protein J
CHMP7 charged multivesicular body protein 7
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CORO7 coronin 7
CRIP1 cysteine-rich protein 1 (intestinal)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNASE1L1 deoxyribonuclease I-like 1
DVL1 dishevelled segment polarity protein 1
ERF Ets2 repressor factor
FAM134C family with sequence similarity 134, member C
FAM179B family with sequence similarity 179, member B
FAM222B family with sequence similarity 222, member B
FAM53B family with sequence similarity 53, member B
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FHOD1 formin homology 2 domain containing 1
GRAMD4 GRAM domain containing 4
GTPBP6 GTP binding protein 6 (putative)
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
IFT46 intraflagellar transport 46
IL17RA interleukin 17 receptor A
IPO4 importin 4
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCTD7 potassium channel tetramerization domain containing 7
KEAP1 kelch-like ECH-associated protein 1
KIAA0556 KIAA0556
KLF11 Kruppel-like factor 11
LAX1 lymphocyte transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MED22 mediator complex subunit 22
MGC12488
MICALL2 MICAL-like 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MON1B MON1 secretory trafficking family member B
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
MYO19 myosin XIX
NT5M 5',3'-nucleotidase, mitochondrial
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACS2 phosphofurin acidic cluster sorting protein 2
PAQR6 progestin and adipoQ receptor family member VI
PHACTR4 phosphatase and actin regulator 4
PHGDH phosphoglycerate dehydrogenase
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRMT7 protein arginine methyltransferase 7
RAB33B RAB33B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM38 RNA binding motif protein 38
RBM42 RNA binding motif protein 42
RECQL4 RecQ protein-like 4
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RWDD3 RWD domain containing 3
S1PR4 sphingosine-1-phosphate receptor 4
SEC31B SEC31 homolog B (S. cerevisiae)
SKI SKI proto-oncogene
SLC35E3 solute carrier family 35, member E3
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNHG20 small nucleolar RNA host gene 20
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPIN1 spindlin 1
SPON2 spondin 2, extracellular matrix protein
TESC tescalcin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM8A transmembrane protein 8A
TOR4A torsin family 4, member A
TRIM28 tripartite motif containing 28
TTBK2 tau tubulin kinase 2
TUBGCP5 tubulin, gamma complex associated protein 5
UBQLN4 ubiquilin 4
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC11 zinc finger, DHHC-type containing 11
ZW10 zw10 kinetochore protein