| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the bisoprolol-5348 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRD6 | ankyrin repeat domain 6 |
| APC | adenomatous polyposis coli |
| APOC1 | apolipoprotein C-I |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARTN | artemin |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTBD7 | BTB (POZ) domain containing 7 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CREBZF | CREB/ATF bZIP transcription factor |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DSC2 | desmocollin 2 |
| EPOR | erythropoietin receptor |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM188A | family with sequence similarity 188, member A |
| FAS | Fas cell surface death receptor |
| FHL1 | four and a half LIM domains 1 |
| FOSL2 | FOS-like antigen 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H1B | histone cluster 1, H1b |
| HMOX1 | heme oxygenase 1 |
| HNMT | histamine N-methyltransferase |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IPO8 | importin 8 |
| IRF9 | interferon regulatory factor 9 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KLK5 | kallikrein-related peptidase 5 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAP4 | microtubule-associated protein 4 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPE1 | metallophosphoesterase 1 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAGLU | N-acetylglucosaminidase, alpha |
| NEK1 | NIMA-related kinase 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NLGN1 | neuroligin 1 |
| NNAT | neuronatin |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OSMR | oncostatin M receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PDAP1 | PDGFA associated protein 1 |
| PDCD2 | programmed cell death 2 |
| PDCD6 | programmed cell death 6 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| RANBP3 | RAN binding protein 3 |
| RECQL5 | RecQ protein-like 5 |
| RSU1 | Ras suppressor protein 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SP110 | SP110 nuclear body protein |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| SVIL | supervillin |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TOP3A | topoisomerase (DNA) III alpha |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TTC33 | tetratricopeptide repeat domain 33 |
| USP20 | ubiquitin specific peptidase 20 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VWA5A | von Willebrand factor A domain containing 5A |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| XAB2 | XPA binding protein 2 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF16 | zinc finger protein 16 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AXIN1 | axin 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CIC | capicua transcriptional repressor |
| CLDN15 | claudin 15 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EGR3 | early growth response 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPHA2 | EPH receptor A2 |
| EVPL | envoplakin |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FPGS | folylpolyglutamate synthase |
| HHLA3 | HERV-H LTR-associating 3 |
| HOXC10 | homeobox C10 |
| HSPA2 | heat shock 70kDa protein 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLC2 | kinesin light chain 2 |
| KLF11 | Kruppel-like factor 11 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC257152 | uncharacterized LOC257152 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEFV | Mediterranean fever |
| MEIS1 | Meis homeobox 1 |
| MT1E | metallothionein 1E |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NBAS | neuroblastoma amplified sequence |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| PGBD5 | piggyBac transposable element derived 5 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PRPH | peripherin |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| PUS1 | pseudouridylate synthase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RPL26 | ribosomal protein L26 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAMP4 | secretory carrier membrane protein 4 |
| SIL1 | SIL1 nucleotide exchange factor |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| TUBA4A | tubulin, alpha 4a |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WLS | wntless Wnt ligand secretion mediator |
| XYLT2 | xylosyltransferase II |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF23 | zinc finger protein 23 |
| ZNF408 | zinc finger protein 408 |
| ZNF432 | zinc finger protein 432 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF7 | zinc finger protein 7 |
| ZW10 | zw10 kinetochore protein |
