blebbistatin-837 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the blebbistatin-837 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD3 abhydrolase domain containing 3
ADAM22 ADAM metallopeptidase domain 22
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADRBK1 adrenergic, beta, receptor kinase 1
AHCYL2 adenosylhomocysteinase-like 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP26 Rho GTPase activating protein 26
ATF3 activating transcription factor 3
ATG13 autophagy related 13
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B9D2 B9 protein domain 2
BICD1 bicaudal D homolog 1 (Drosophila)
C14ORF93 chromosome 14 open reading frame 93
CACYBP calcyclin binding protein
CALCOCO1 calcium binding and coiled-coil domain 1
CALML3 calmodulin-like 3
CCDC170 coiled-coil domain containing 170
CD52 CD52 molecule
CEP164 centrosomal protein 164kDa
CLDN15 claudin 15
CRELD1 cysteine-rich with EGF-like domains 1
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DMWD dystrophia myotonica, WD repeat containing
DOCK6 dedicator of cytokinesis 6
DRD1 dopamine receptor D1
EDRF1 erythroid differentiation regulatory factor 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETNK2 ethanolamine kinase 2
FAM134B family with sequence similarity 134, member B
FAXDC2 fatty acid hydroxylase domain containing 2
FBXW12 F-box and WD repeat domain containing 12
FER1L4 fer-1-like family member 4, pseudogene (functional)
FLT4 fms-related tyrosine kinase 4
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GRM8 glutamate receptor, metabotropic 8
GSAP gamma-secretase activating protein
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HMOX1 heme oxygenase 1
HRASLS2 HRAS-like suppressor 2
IPO8 importin 8
IQCK IQ motif containing K
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD12 potassium channel tetramerization domain containing 12
KLF9 Kruppel-like factor 9
KLHL24 kelch-like family member 24
LIG4 ligase IV, DNA, ATP-dependent
LIMK2 LIM domain kinase 2
LOC57399 uncharacterized gastric protein ZA52P
LPAR4 lysophosphatidic acid receptor 4
MAP7D3 MAP7 domain containing 3
MARC2 mitochondrial amidoxime reducing component 2
MARS methionyl-tRNA synthetase
METTL7A methyltransferase like 7A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP19 matrix metallopeptidase 19
NAG18 NAG18 mRNA
NCR2 natural cytotoxicity triggering receptor 2
NF1 neurofibromin 1
NLGN1 neuroligin 1
ORC5 origin recognition complex, subunit 5
PADI1 peptidyl arginine deiminase, type I
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLK4 polo-like kinase 4
PRB1 proline-rich protein BstNI subfamily 1
PROS1 protein S (alpha)
RABGAP1L RAB GTPase activating protein 1-like
RBM5 RNA binding motif protein 5
RGS12 regulator of G-protein signaling 12
RPS3A ribosomal protein S3A
RTEL1 regulator of telomere elongation helicase 1
RUFY2 RUN and FYVE domain containing 2
SAPCD1 suppressor APC domain containing 1
SHB Src homology 2 domain containing adaptor protein B
SIM2 single-minded family bHLH transcription factor 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC38A7 solute carrier family 38, member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STYK1 serine/threonine/tyrosine kinase 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFF2 trefoil factor 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAIP TRAF interacting protein
TRIP11 thyroid hormone receptor interactor 11
ZBTB43 zinc finger and BTB domain containing 43
ZNF219 zinc finger protein 219
ZNF253 zinc finger protein 253
ZNF43 zinc finger protein 43
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTN4 actinin, alpha 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AEN apoptosis enhancing nuclease
AGO3 argonaute RISC catalytic component 3
APIP APAF1 interacting protein
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP13A2 ATPase type 13A2
C1ORF115 chromosome 1 open reading frame 115
C21ORF91 chromosome 21 open reading frame 91
CEP72 centrosomal protein 72kDa
CEP97 centrosomal protein 97kDa
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCP1A decapping mRNA 1A
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAL4 dynein, axonemal, light chain 4
DNALI1 dynein, axonemal, light intermediate chain 1
EHBP1L1 EH domain binding protein 1-like 1
ELOVL4 ELOVL fatty acid elongase 4
FICD FIC domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FRS2 fibroblast growth factor receptor substrate 2
GALT galactose-1-phosphate uridylyltransferase
GAR1 GAR1 ribonucleoprotein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPSE heparanase
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR2 interferon (alpha, beta and omega) receptor 2
INHBB inhibin, beta B
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KRT15 keratin 15, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
MAP6D1 MAP6 domain containing 1
MATK megakaryocyte-associated tyrosine kinase
MED15 mediator complex subunit 15
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIS18BP1 MIS18 binding protein 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MVD mevalonate (diphospho) decarboxylase
NARFL nuclear prelamin A recognition factor-like
NBEAL2 neurobeachin-like 2
NECAP2 NECAP endocytosis associated 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLRX1 NLR family member X1
NPY5R neuropeptide Y receptor Y5
PARP16 poly (ADP-ribose) polymerase family, member 16
PGM1 phosphoglucomutase 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLA2G15 phospholipase A2, group XV
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKX protein kinase, X-linked
PRR7 proline rich 7 (synaptic)
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB33B RAB33B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L RAD54-like (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
REEP4 receptor accessory protein 4
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMAD7 SMAD family member 7
SNORA21 small nucleolar RNA, H/ACA box 21
SYBU syntabulin (syntaxin-interacting)
TAGLN transgelin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOP1 thimet oligopeptidase 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM109 transmembrane protein 109
TMEM38B transmembrane protein 38B
TNRC6B trinucleotide repeat containing 6B
TRIM25 tripartite motif containing 25
TSPYL2 TSPY-like 2
USP6NL USP6 N-terminal like
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR25 WD repeat domain 25
WDR76 WD repeat domain 76
WWC2 WW and C2 domain containing 2
XAB2 XPA binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF580 zinc finger protein 580
ZNF592 zinc finger protein 592
ZNF668 zinc finger protein 668
ZNF813 zinc finger protein 813