bleomycin-sulfate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

711 genes differentially expressed following the bleomycin-sulfate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TBP TATA box binding protein 7.25573
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1 6.96641
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 6.58166
SPTAN1 spectrin, alpha, non-erythrocytic 1 6.52274
DIPK1A divergent protein kinase domain 1A 6.131
FSD1 fibronectin type III and SPRY domain containing 1 5.85273
DIXDC1 DIX domain containing 1 5.65081
CNKSR1 connector enhancer of kinase suppressor of Ras 1 5.55682
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 5.47785
MYL7 myosin, light chain 7, regulatory 5.30948
RPS25 ribosomal protein S25 5.27884
MEA1 male-enhanced antigen 1 5.25303
CTF1 cardiotrophin 1 5.22197
MTNR1B melatonin receptor 1B 5.21211
HOXC11 homeobox C11 5.1418
BPHL biphenyl hydrolase-like (serine hydrolase) 5.11802
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 5.08053
NXPH4 neurexophilin 4 5.04351
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 4.98827
NDRG1 N-myc downstream regulated 1 4.97327
CTSV cathepsin V 4.9337
EI24 etoposide induced 2.4 4.92492
CXCR4 chemokine (C-X-C motif) receptor 4 4.9096
ST14 suppression of tumorigenicity 14 (colon carcinoma) 4.87987
SCAMP2 secretory carrier membrane protein 2 4.87193
SNX29 sorting nexin 29 4.8468
SLC66A3 solute carrier family 66 member 3 4.81814
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 4.80079
FBXL18 F-box and leucine-rich repeat protein 18 4.79802
CADM1 cell adhesion molecule 1 4.75988
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 4.74913
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 4.7313
DSTYK dual serine/threonine and tyrosine protein kinase 4.68515
PRKD3 protein kinase D3 4.64293
SPTBN4 spectrin, beta, non-erythrocytic 4 4.62148
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 4.61002
LAMB3 laminin, beta 3 4.60468
ZFR2 zinc finger RNA binding protein 2 4.59005
FAM50B family with sequence similarity 50, member B 4.57372
IGSF6 immunoglobulin superfamily, member 6 4.56936
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 4.56033
GBP2 guanylate binding protein 2, interferon-inducible 4.54344
SF3B4 splicing factor 3b, subunit 4, 49kDa 4.53077
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.53008
ARPC5L actin related protein 2/3 complex, subunit 5-like 4.51686
NPC2 Niemann-Pick disease, type C2 4.49864
CCL15 chemokine (C-C motif) ligand 15 4.49037
POLR1HASP POLR1H antisense, pseudogene 4.46691
CIDEA cell death-inducing DFFA-like effector a 4.43349
ZNF280B zinc finger protein 280B 4.42955
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 4.42362
TPM2 tropomyosin 2 (beta) 4.40147
LYZL6 lysozyme-like 6 4.39899
PINK1 PTEN induced putative kinase 1 4.38365
NELFE negative elongation factor complex member E 4.36343
EML1 echinoderm microtubule associated protein like 1 4.3524
ZNF493 zinc finger protein 493 4.3467
RPL37A ribosomal protein L37a 4.34191
ANKRD10 ankyrin repeat domain 10 4.31158
RPS13 ribosomal protein S13 4.30456
BRS3 bombesin-like receptor 3 4.27145
GPRIN2 G protein regulated inducer of neurite outgrowth 2 4.24331
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 4.20837
EFR3B EFR3 homolog B (S. cerevisiae) 4.20382
RPS14 ribosomal protein S14 4.18065
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 4.17987
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 4.1783
SIPA1L3 signal-induced proliferation-associated 1 like 3 4.16586
HHAT hedgehog acyltransferase 4.14321
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 4.13017
HOXC4 homeobox C4 4.12732
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 4.12706
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 4.12648
EAPP E2F-associated phosphoprotein 4.10423
PTK7 protein tyrosine kinase 7 (inactive) 4.10192
ZPBP zona pellucida binding protein 4.09313
RPL22 ribosomal protein L22 4.08471
MPPED1 metallophosphoesterase domain containing 1 4.08042
RPS5 ribosomal protein S5 4.07474
STK19 serine/threonine kinase 19 4.06489
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 4.05323
ZNF623 zinc finger protein 623 4.04791
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 4.04058
KDM3A lysine (K)-specific demethylase 3A 4.03713
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 4.0307
PALMD palmdelphin 4.01516
SAP30L-AS1 SAP30L antisense RNA 1 (head to head) 4.00577
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 4.00185
FSTL4 follistatin-like 4 3.99972
TP73-AS1 TP73 antisense RNA 1 3.99571
GPR137 G protein-coupled receptor 137 3.99052
PURA purine-rich element binding protein A 3.98791
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 3.98075
BLNK B-cell linker 3.96124
CGB3 chorionic gonadotropin subunit beta 3 3.95883
LIMA1 LIM domain and actin binding 1 3.9526
PRPF3 pre-mRNA processing factor 3 3.93518
ACAT2 acetyl-CoA acetyltransferase 2 3.92201
SHARPIN SHANK-associated RH domain interactor 3.91582
DUSP2 dual specificity phosphatase 2 3.90625
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 3.90206
NSFL1C NSFL1 (p97) cofactor (p47) 3.89624
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 3.89522
TGM4 transglutaminase 4 3.87622
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 3.86926
CPM carboxypeptidase M 3.86146
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.85098
CTNNBIP1 catenin, beta interacting protein 1 3.84153
RNH1 ribonuclease/angiogenin inhibitor 1 3.83531
DTX3 deltex 3, E3 ubiquitin ligase 3.83475
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 3.82403
GAST gastrin 3.82304
TUBA1A tubulin, alpha 1a 3.81988
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 3.81944
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 3.81044
JHY junctional cadherin complex regulator 3.80689
FOXK2 forkhead box K2 3.80106
C6ORF47 chromosome 6 open reading frame 47 3.79929
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 3.79186
SLC17A4 solute carrier family 17, member 4 3.78727
PLA2G2E phospholipase A2, group IIE 3.78586
RPL39L ribosomal protein L39-like 3.7797
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.77683
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.7743
SMG6 SMG6 nonsense mediated mRNA decay factor 3.76426
CORO2A coronin, actin binding protein, 2A 3.74309
ZBTB43 zinc finger and BTB domain containing 43 3.72995
PRPF4 pre-mRNA processing factor 4 3.72916
IL6R interleukin 6 receptor 3.72101
ACTN3 actinin, alpha 3 (gene/pseudogene) 3.70827
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 3.70051
CDC42 cell division cycle 42 3.69974
SDAD1 SDA1 domain containing 1 3.69467
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 3.694
DKKL1 dickkopf-like 1 3.68817
TCHH trichohyalin 3.67948
GPX5 glutathione peroxidase 5 3.67772
NOS2 nitric oxide synthase 2, inducible 3.66064
PKM pyruvate kinase, muscle 3.66049
CCHCR1 coiled-coil alpha-helical rod protein 1 3.65903
HOXA4 homeobox A4 3.65364
PFDN6 prefoldin subunit 6 3.65362
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.65201
RNF115 ring finger protein 115 3.6517
MEF2D myocyte enhancer factor 2D 3.64388
MRPL2 mitochondrial ribosomal protein L2 3.63758
CDK5RAP1 CDK5 regulatory subunit associated protein 1 3.63684
NHLH1 nescient helix loop helix 1 3.63615
DNAAF8 dynein axonemal assembly factor 8 3.63305
NFRKB nuclear factor related to kappaB binding protein 3.626
ZCWPW1 zinc finger, CW type with PWWP domain 1 3.62486
RPL27A ribosomal protein L27a 3.62322
HSF4 heat shock transcription factor 4 3.62134
ALDOC aldolase C, fructose-bisphosphate 3.62086
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 3.60921
GLB1L2 galactosidase, beta 1-like 2 3.60841
ZBTB44 zinc finger and BTB domain containing 44 3.60395
PDLIM5 PDZ and LIM domain 5 3.60355
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 3.59586
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 3.5949
KRT5 keratin 5, type II 3.59462
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 3.58865
MTF2 metal response element binding transcription factor 2 3.58002
TERT telomerase reverse transcriptase 3.57117
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.57081
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 3.56818
C8ORF33 chromosome 8 open reading frame 33 3.56682
PHF20L1 PHD finger protein 20-like 1 3.56081
MPZL2 myelin protein zero-like 2 3.551
SRP54 signal recognition particle 54kDa 3.54888
SRCAP Snf2-related CREBBP activator protein 3.54593
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 3.53725
CSF3 colony stimulating factor 3 (granulocyte) 3.52713
FMO4 flavin containing monooxygenase 4 3.52327
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 3.52063
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 3.50904
SIDT1 SID1 transmembrane family, member 1 3.50836
CAST calpastatin 3.50418
NOS1 nitric oxide synthase 1 (neuronal) 3.5025
REEP5 receptor accessory protein 5 3.49567
TESK2 testis-specific kinase 2 3.49555
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 3.49506
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 3.4895
STK17A serine/threonine kinase 17a 3.48754
TRAPPC4 trafficking protein particle complex 4 3.48561
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 3.48274
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 3.48214
EXOSC4 exosome component 4 3.48093
ENO1 enolase 1, (alpha) 3.47713
KRTAP5-9 keratin associated protein 5-9 3.47542
MYOM2 myomesin 2 3.46473
LEP leptin 3.46237
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 3.45984
ARNT aryl hydrocarbon receptor nuclear translocator 3.45719
RPS3 ribosomal protein S3 3.45591
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 3.45565
FKBP14 FK506 binding protein 14, 22 kDa 3.45416
TCL1A T-cell leukemia/lymphoma 1A 3.43615
CUTC cutC copper transporter 3.43342
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 3.42937
BOP1 block of proliferation 1 3.42527
CYRIB CYFIP related Rac1 interactor B 3.42391
LAMC3 laminin, gamma 3 3.42157
AKAP12 A kinase (PRKA) anchor protein 12 3.4209
RABIF RAB interacting factor 3.41939
ACRV1 acrosomal vesicle protein 1 3.414
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 3.40291
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 3.39857
MYL10 myosin, light chain 10, regulatory 3.39703
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 3.39562
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 3.39491
EGFL7 EGF-like-domain, multiple 7 3.39442
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 3.39025
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 3.38396
SELENOP selenoprotein P 3.37861
BRD7P3 bromodomain containing 7 pseudogene 3 3.37368
RPS24 ribosomal protein S24 3.37328
RABGAP1 RAB GTPase activating protein 1 3.37323
ATF7IP2 activating transcription factor 7 interacting protein 2 3.3654
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 3.36305
H2AC8 H2A clustered histone 8 3.36282
NACA nascent polypeptide-associated complex alpha subunit 3.35942
RIPK4 receptor-interacting serine-threonine kinase 4 3.35077
SKI SKI proto-oncogene 3.34687
GJB5 gap junction protein, beta 5, 31.1kDa 3.34623
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 3.34555
IL1A interleukin 1, alpha 3.34393
FMO5 flavin containing monooxygenase 5 3.34382
ZPR1 ZPR1 zinc finger 3.34081
CAPN3 calpain 3, (p94) 3.34006
NKIRAS2 NFKB inhibitor interacting Ras-like 2 3.33804
EDA ectodysplasin A 3.33631
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.33369
GJA8 gap junction protein, alpha 8, 50kDa 3.33091
PCDHGA9 protocadherin gamma subfamily A, 9 3.32819
KRT76 keratin 76, type II 3.3275
RAB28 RAB28, member RAS oncogene family 3.32715
SLC35F2 solute carrier family 35, member F2 3.323
VEGFB vascular endothelial growth factor B 3.32006
TDRKH tudor and KH domain containing 3.31916
BFAR bifunctional apoptosis regulator 3.31795
IGSF3 immunoglobulin superfamily, member 3 3.3021
POMC proopiomelanocortin 3.30005
MAP7D1 MAP7 domain containing 1 3.29801
EFR3A EFR3 homolog A (S. cerevisiae) 3.29648
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 3.28958
HK2 hexokinase 2 3.28926
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 3.27495
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 3.27306
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 3.27198
CNMD chondromodulin 3.26862
HDAC9 histone deacetylase 9 3.26657
EDDM3A epididymal protein 3A 3.26369
PRR34 proline rich 34 3.26098
AAAS achalasia, adrenocortical insufficiency, alacrimia 3.26097
PMVK phosphomevalonate kinase 3.25904
YBX2 Y box binding protein 2 3.25874
ADGRL2 adhesion G protein-coupled receptor L2 3.25739
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 3.25642
ZNF7 zinc finger protein 7 3.25426
CCNE2 cyclin E2 3.24521
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 3.2422
OPLAH 5-oxoprolinase (ATP-hydrolysing) 3.23871
GPR162 G protein-coupled receptor 162 3.2355
FN3KRP fructosamine 3 kinase related protein 3.2342
ZSWIM1 zinc finger, SWIM-type containing 1 3.23105
EFNA4 ephrin-A4 3.22916
ADCY2 adenylate cyclase 2 (brain) 3.22848
PGK2 phosphoglycerate kinase 2 3.22745
DENND6B DENN/MADD domain containing 6B 3.2255
FRY furry homolog (Drosophila) 3.22052
SPAG4 sperm associated antigen 4 3.21616
FBXO42 F-box protein 42 3.21567
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 3.21273
GAN gigaxonin 3.21242
ELP5 elongator acetyltransferase complex subunit 5 3.20888
ACR acrosin 3.2073
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 3.20593
IL22 interleukin 22 3.20394
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 3.20317
SLC35E1 solute carrier family 35, member E1 3.20306
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 3.19793
UNC5C unc-5 homolog C (C. elegans) 3.19736
KALRN kalirin, RhoGEF kinase 3.19653
SETD1A SET domain containing 1A 3.19255
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 3.19222
ELOA elongin A 3.1895
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 3.18599
PXDC1 PX domain containing 1 3.18349
CAMKMT calmodulin-lysine N-methyltransferase 3.18051
CCDC57 coiled-coil domain containing 57 3.17945
RHBG Rh family, B glycoprotein (gene/pseudogene) 3.17937
NEU3 sialidase 3 (membrane sialidase) 3.17714
HINFP histone H4 transcription factor 3.17708
SLC39A4 solute carrier family 39 (zinc transporter), member 4 3.17561
CREBZF CREB/ATF bZIP transcription factor 3.17395
ZFYVE9 zinc finger, FYVE domain containing 9 3.16713
SYK spleen tyrosine kinase 3.16706
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.16443
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 3.159
TNS4 tensin 4 3.15835
VIM vimentin 3.15825
LY9 lymphocyte antigen 9 3.1559
CD40LG CD40 ligand 3.15455
THAP3 THAP domain containing, apoptosis associated protein 3 3.1539
IRGQ immunity-related GTPase family, Q 3.14897
MN1 meningioma (disrupted in balanced translocation) 1 3.14562
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 3.14186
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 3.14147
TSPY1 testis specific protein, Y-linked 1 3.13977
ATXN3 ataxin 3 3.13817
RPS11 ribosomal protein S11 3.13416
CCDC71 coiled-coil domain containing 71 3.12772
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 3.12248
IRF9 interferon regulatory factor 9 3.1195
NLRP3 NLR family, pyrin domain containing 3 3.11887
REXO2 RNA exonuclease 2 3.11841
HILPDA hypoxia inducible lipid droplet-associated 3.11261
KLK5 kallikrein-related peptidase 5 3.11202
GBX1 gastrulation brain homeobox 1 3.11071
TMC5 transmembrane channel-like 5 3.11071
SYNGR1 synaptogyrin 1 3.10928
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 3.10685
NEMP1 nuclear envelope integral membrane protein 1 3.10107
SAFB2 scaffold attachment factor B2 3.10015
CCDC69 coiled-coil domain containing 69 3.09892
ANKH ANKH inorganic pyrophosphate transport regulator 3.0989
TPTE transmembrane phosphatase with tensin homology 3.09829
PTN pleiotrophin 3.09754
KDM4A lysine (K)-specific demethylase 4A 3.09709
DSE dermatan sulfate epimerase 3.09442
PIGR polymeric immunoglobulin receptor 3.091
CST8 cystatin 8 (cystatin-related epididymal specific) 3.08834
MYH11 myosin, heavy chain 11, smooth muscle 3.08563
ACKR2 atypical chemokine receptor 2 3.08422
GAS6 growth arrest-specific 6 3.08398
CIITA class II, major histocompatibility complex, transactivator 3.07905
SOX9 SRY (sex determining region Y)-box 9 3.07831
DKFZP586I1420 uncharacterized protein DKFZp586I1420 3.07726
NOL10 nucleolar protein 10 3.07716
OTUD3 OTU deubiquitinase 3 3.07368
ARCN1 archain 1 3.07313
EDN2 endothelin 2 3.07174
TEX11 testis expressed 11 3.06954
FCF1 FCF1 rRNA-processing protein 3.06948
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 3.06892
GJC2 gap junction protein, gamma 2, 47kDa 3.06847
ARSD arylsulfatase D 3.06644
UBE2G2 ubiquitin-conjugating enzyme E2G 2 3.06399
DNMBP dynamin binding protein 3.06261
GPR25 G protein-coupled receptor 25 3.05973
TMEM243 transmembrane protein 243, mitochondrial 3.05829
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.05458
PTCRA pre T-cell antigen receptor alpha 3.048
DNASE1L2 deoxyribonuclease I-like 2 3.04637
PCDHGA3 protocadherin gamma subfamily A, 3 3.04547
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.04145
FRS2 fibroblast growth factor receptor substrate 2 3.03907
VEZT vezatin, adherens junctions transmembrane protein 3.03749
ESR2 estrogen receptor 2 (ER beta) 3.03507
NOTCH3 notch 3 3.03324
FBP1 fructose-1,6-bisphosphatase 1 3.03027
MRNIP MRN complex interacting protein 3.02986
TKFC triokinase/FMN cyclase 3.02953
SSUH2 ssu-2 homolog (C. elegans) 3.02388
ANXA11 annexin A11 3.02304
XAF1 XIAP associated factor 1 3.02215
KDM7A lysine (K)-specific demethylase 7A 3.02148
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 3.02014
AGO2 argonaute RISC catalytic component 2 3.0186
CFDP1 craniofacial development protein 1 3.0152
PDK2 pyruvate dehydrogenase kinase, isozyme 2 3.01268
SEPTIN6 septin 6 3.0122
PRDM13 PR domain containing 13 3.00783
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 3.00732
GPX7 glutathione peroxidase 7 3.00469
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.00426
ZNF671 zinc finger protein 671 3.00295
AVPR1B arginine vasopressin receptor 1B 3.00205
ENPEP glutamyl aminopeptidase (aminopeptidase A) 3.00168

decreased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -9.03251
SFRP5 secreted frizzled-related protein 5 -7.06708
DENND1A DENN/MADD domain containing 1A -6.95123
PRKCH protein kinase C, eta -6.41893
HRH3 histamine receptor H3 -6.26978
CEP170 centrosomal protein 170kDa -6.15065
CSN3 casein kappa -5.7404
PNLIP pancreatic lipase -5.43716
ARL8B ADP-ribosylation factor-like 8B -5.26471
XPO1 exportin 1 -5.24108
TCIM transcriptional and immune response regulator -5.22985
FH fumarate hydratase -5.21723
CELA2B chymotrypsin-like elastase family, member 2B -5.11885
PTK2B protein tyrosine kinase 2 beta -5.00179
PPARG peroxisome proliferator-activated receptor gamma -4.93908
GSE1 Gse1 coiled-coil protein -4.90735
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -4.89212
CHM choroideremia (Rab escort protein 1) -4.83254
CEP57 centrosomal protein 57kDa -4.82747
PRSS1 protease, serine, 1 (trypsin 1) -4.78395
H1-10 H1.10 linker histone -4.74985
STIMATE STIM activating enhancer -4.73152
AKT1 v-akt murine thymoma viral oncogene homolog 1 -4.68144
TAGLN3 transgelin 3 -4.62803
SNX11 sorting nexin 11 -4.62457
CISH cytokine inducible SH2-containing protein -4.6138
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -4.60932
CELF2 CUGBP, Elav-like family member 2 -4.59812
GORASP1 golgi reassembly stacking protein 1, 65kDa -4.59141
CD244 CD244 molecule, natural killer cell receptor 2B4 -4.56524
CELA2A chymotrypsin-like elastase family, member 2A -4.54021
NRTN neurturin -4.52808
MYD88 myeloid differentiation primary response 88 -4.45973
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -4.45659
ENOSF1 enolase superfamily member 1 -4.45047
ETHE1 ethylmalonic encephalopathy 1 -4.44826
UBXN4 UBX domain protein 4 -4.44197
GRM1 glutamate receptor, metabotropic 1 -4.43056
IL6ST interleukin 6 signal transducer -4.41866
SNRPA small nuclear ribonucleoprotein polypeptide A -4.41483
PSIP1 PC4 and SFRS1 interacting protein 1 -4.39396
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -4.3765
CD7 CD7 molecule -4.3508
PNPLA3 patatin-like phospholipase domain containing 3 -4.35004
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -4.3498
RGS7 regulator of G-protein signaling 7 -4.31455
TECTA tectorin alpha -4.28768
RRAGB Ras-related GTP binding B -4.27658
GRAP2 GRB2-related adaptor protein 2 -4.27546
NAGLU N-acetylglucosaminidase, alpha -4.27238
CAPN1 calpain 1, (mu/I) large subunit -4.25916
BCL2 B-cell CLL/lymphoma 2 -4.23688
SNCA synuclein, alpha (non A4 component of amyloid precursor) -4.23547
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -4.23467
UBA7 ubiquitin-like modifier activating enzyme 7 -4.20103
CTRC chymotrypsin C (caldecrin) -4.19045
SEPTIN2 septin 2 -4.18465
EIF1 eukaryotic translation initiation factor 1 -4.16888
PARD3 par-3 family cell polarity regulator -4.1576
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -4.15545
TIMP1 TIMP metallopeptidase inhibitor 1 -4.1431
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -4.12391
COASY CoA synthase -4.10448
ARID4B AT rich interactive domain 4B (RBP1-like) -4.09442
REPIN1 replication initiator 1 -4.07302
BCLAF1 BCL2-associated transcription factor 1 -4.07153
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -4.06932
RPP38 ribonuclease P/MRP 38kDa subunit -4.05113
GLI2 GLI family zinc finger 2 -4.03608
SASH3 SAM and SH3 domain containing 3 -4.01976
OGDHL oxoglutarate dehydrogenase-like -4.01256
SLC12A8 solute carrier family 12, member 8 -4.01035
VGF VGF nerve growth factor inducible -4.00702
ARF4 ADP-ribosylation factor 4 -4.00018
IDE insulin-degrading enzyme -3.99409
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -3.9868
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -3.97974
CALB1 calbindin 1, 28kDa -3.97289
MTMR8 myotubularin related protein 8 -3.9698
LARS2 leucyl-tRNA synthetase 2, mitochondrial -3.95704
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.94742
PLA2G1B phospholipase A2, group IB (pancreas) -3.93514
GPR6 G protein-coupled receptor 6 -3.93296
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -3.93139
SNAP25 synaptosomal-associated protein, 25kDa -3.92357
ZNF23 zinc finger protein 23 -3.91551
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -3.90871
POLR1D polymerase (RNA) I polypeptide D, 16kDa -3.89026
ZNF480 zinc finger protein 480 -3.88217
TLE5 TLE family member 5, transcriptional modulator -3.87837
NGFR nerve growth factor receptor -3.87401
CRYBA2 crystallin, beta A2 -3.87009
MGMT O-6-methylguanine-DNA methyltransferase -3.86799
DYNLT3 dynein, light chain, Tctex-type 3 -3.86231
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 -3.85696
DLD dihydrolipoamide dehydrogenase -3.85266
CIAO3 cytosolic iron-sulfur assembly component 3 -3.84743
NAMPT nicotinamide phosphoribosyltransferase -3.83223
TMF1 TATA element modulatory factor 1 -3.82185
RALYL RALY RNA binding protein-like -3.82081
FHIP2B FHF complex subunit HOOK interacting protein 2B -3.81094
THSD4 thrombospondin, type I, domain containing 4 -3.80692
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -3.80193
UBA3 ubiquitin-like modifier activating enzyme 3 -3.79724
TARP TCR gamma alternate reading frame protein -3.79435
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -3.78874
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -3.7859
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -3.78289
OSGIN2 oxidative stress induced growth inhibitor family member 2 -3.77953
LALBA lactalbumin, alpha- -3.77548
PPARA peroxisome proliferator-activated receptor alpha -3.77325
PHF10 PHD finger protein 10 -3.7731
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -3.76685
XPO7 exportin 7 -3.76455
CD96 CD96 molecule -3.76265
C4ORF19 chromosome 4 open reading frame 19 -3.75691
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -3.75176
SELENOW selenoprotein W -3.73606
EXD2 exonuclease 3'-5' domain containing 2 -3.73455
CNBP CCHC-type zinc finger, nucleic acid binding protein -3.73335
GPHN gephyrin -3.73206
PNLIPRP1 pancreatic lipase-related protein 1 -3.71689
CDC45 cell division cycle 45 -3.71366
KIRREL1 kirre like nephrin family adhesion molecule 1 -3.70552
TOR1A torsin family 1, member A (torsin A) -3.69101
RCL1 RNA terminal phosphate cyclase-like 1 -3.6902
LUZP4 leucine zipper protein 4 -3.68253
CPA1 carboxypeptidase A1 (pancreatic) -3.67885
TPD52L2 tumor protein D52-like 2 -3.67742
MLX MLX, MAX dimerization protein -3.67059
CTRB2 chymotrypsinogen B2 -3.65572
CFAP20 cilia and flagella associated protein 20 -3.65571
SORD sorbitol dehydrogenase -3.64939
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -3.64497
SRSF5 serine/arginine-rich splicing factor 5 -3.64404
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -3.64375
FXN frataxin -3.64083
ABHD10 abhydrolase domain containing 10 -3.62662
KRT38 keratin 38, type I -3.61745
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -3.61367
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -3.60822
MID1 midline 1 -3.60062
NCS1 neuronal calcium sensor 1 -3.59706
MINDY1 MINDY lysine 48 deubiquitinase 1 -3.59454
IL17RB interleukin 17 receptor B -3.59419
APTX aprataxin -3.59398
NME3 NME/NM23 nucleoside diphosphate kinase 3 -3.5873
LGI1 leucine-rich, glioma inactivated 1 -3.58444
PEF1 penta-EF-hand domain containing 1 -3.57639
EGFR epidermal growth factor receptor -3.57367
ANKRD53 ankyrin repeat domain 53 -3.57333
PLA2R1 phospholipase A2 receptor 1, 180kDa -3.56501
IKZF2 IKAROS family zinc finger 2 (Helios) -3.56204
S100A5 S100 calcium binding protein A5 -3.56135
H3-3B H3.3 histone B -3.55907
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -3.55736
NBEAL2 neurobeachin-like 2 -3.55732
MSL1 male-specific lethal 1 homolog (Drosophila) -3.52384
MLH1 mutL homolog 1 -3.52104
PLP1 proteolipid protein 1 -3.51622
PCSK1 proprotein convertase subtilisin/kexin type 1 -3.51175
ADGRL3 adhesion G protein-coupled receptor L3 -3.51138
CTAGE11P CTAGE family, member 11, pseudogene -3.51091
NOL4 nucleolar protein 4 -3.5099
CADM3 cell adhesion molecule 3 -3.48708
CLDN14 claudin 14 -3.47828
MTMR4 myotubularin related protein 4 -3.4763
STAT5A signal transducer and activator of transcription 5A -3.47357
ELMO1 engulfment and cell motility 1 -3.4706
ABR active BCR-related -3.47043
UBASH3A ubiquitin associated and SH3 domain containing A -3.4684
PCGF2 polycomb group ring finger 2 -3.46182
LZTFL1 leucine zipper transcription factor-like 1 -3.46156
MID1IP1 MID1 interacting protein 1 -3.45986
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 -3.44914
SST somatostatin -3.44325
HYAL1 hyaluronoglucosaminidase 1 -3.42961
ATXN10 ataxin 10 -3.42807
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -3.4277
CHML choroideremia-like (Rab escort protein 2) -3.42036
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -3.40735
PLIN2 perilipin 2 -3.4032
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled -3.40017
ZNF302 zinc finger protein 302 -3.39465
FGD1 FYVE, RhoGEF and PH domain containing 1 -3.3919
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.39042
IL1R2 interleukin 1 receptor, type II -3.38357
ESD esterase D -3.37982
NEK4 NIMA-related kinase 4 -3.37812
PIERCE1 piercer of microtubule wall 1 -3.37782
INS insulin -3.37377
KERA keratocan -3.36942
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -3.36775
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -3.3638
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 -3.36207
MTIF2 mitochondrial translational initiation factor 2 -3.35839
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled -3.35815
PAPOLB poly(A) polymerase beta (testis specific) -3.35683
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -3.35441
UGT8 UDP glycosyltransferase 8 -3.35362
OGFRL1 opioid growth factor receptor-like 1 -3.34794
ZNF484 zinc finger protein 484 -3.3474
RIMBP2 RIMS binding protein 2 -3.34703
SETD2 SET domain containing 2 -3.34603
GRM6 glutamate receptor, metabotropic 6 -3.33979
CSN2 casein beta -3.33756
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -3.33303
RHOA ras homolog family member A -3.33052
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -3.32601
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -3.3258
GSTM1 glutathione S-transferase mu 1 -3.32561
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.31946
MEOX2 mesenchyme homeobox 2 -3.31812
TRAK1 trafficking protein, kinesin binding 1 -3.3169
GLT8D1 glycosyltransferase 8 domain containing 1 -3.31131
MPZL1 myelin protein zero-like 1 -3.3074
FTO fat mass and obesity associated -3.30597
ODAM odontogenic, ameloblast asssociated -3.30281
FAM30A family with sequence similarity 30 member A -3.29536
QSER1 glutamine and serine rich 1 -3.28961
MTARC2 mitochondrial amidoxime reducing component 2 -3.28878
TTLL12 tubulin tyrosine ligase-like family member 12 -3.28803
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -3.28089
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -3.27933
CD320 CD320 molecule -3.27898
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -3.27714
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein -3.2765
HMG20B high mobility group 20B -3.27281
RBM26 RNA binding motif protein 26 -3.27157
MYL1 myosin, light chain 1, alkali; skeletal, fast -3.2697
ARHGAP6 Rho GTPase activating protein 6 -3.26872
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -3.26812
PNLIPRP2 pancreatic lipase-related protein 2 -3.26643
KDM4C lysine (K)-specific demethylase 4C -3.26032
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -3.25928
SIRAL2 SIR2 antiphage like 2 -3.25792
AMD1 adenosylmethionine decarboxylase 1 -3.25108
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -3.24907
PRKX protein kinase, X-linked -3.24862
ZNF146 zinc finger protein 146 -3.24646
APEH acylaminoacyl-peptide hydrolase -3.24354
SMCO4 single-pass membrane protein with coiled-coil domains 4 -3.2424
SNUPN snurportin 1 -3.24011
SLC25A38 solute carrier family 25, member 38 -3.23698
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -3.23203
SCO2 SCO2 cytochrome c oxidase assembly protein -3.22948
PDIA5 protein disulfide isomerase family A, member 5 -3.2277
NUP54 nucleoporin 54kDa -3.22693
CERS6 ceramide synthase 6 -3.2249
TSPAN4 tetraspanin 4 -3.2243
CELA3A chymotrypsin-like elastase family, member 3A -3.21841
PDHX pyruvate dehydrogenase complex, component X -3.21035
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.20975
UNG uracil-DNA glycosylase -3.2077
PLK4 polo-like kinase 4 -3.20564
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -3.19957
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -3.19856
NEK1 NIMA-related kinase 1 -3.19574
CADPS Ca++-dependent secretion activator -3.18476
FUBP3 far upstream element (FUSE) binding protein 3 -3.18202
SOX14 SRY (sex determining region Y)-box 14 -3.17916
ATP2A3 ATPase, Ca++ transporting, ubiquitous -3.17546
NISCH nischarin -3.17338
POLQ polymerase (DNA directed), theta -3.17337
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -3.17186
BAHCC1 BAH domain and coiled-coil containing 1 -3.16332
ZIC1 Zic family member 1 -3.16244
TBCE tubulin folding cofactor E -3.16126
THAP7 THAP domain containing 7 -3.15952
GPR85 G protein-coupled receptor 85 -3.15069
BRCA1 breast cancer 1, early onset -3.15054
TBCD tubulin folding cofactor D -3.15029
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -3.14872
DCX doublecortin -3.14472
GPRASP1 G protein-coupled receptor associated sorting protein 1 -3.14382
GSTM2 glutathione S-transferase mu 2 (muscle) -3.13346
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -3.13233
POGLUT1 protein O-glucosyltransferase 1 -3.1309
ZNF268 zinc finger protein 268 -3.12209
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -3.11667
PARP3 poly (ADP-ribose) polymerase family, member 3 -3.11129
MYO3A myosin IIIA -3.10888
ADD3 adducin 3 (gamma) -3.1016
SENP7 SUMO1/sentrin specific peptidase 7 -3.10128
MMRN1 multimerin 1 -3.10016
EIPR1 EARP complex and GARP complex interacting protein 1 -3.10008
TUBGCP4 tubulin, gamma complex associated protein 4 -3.09966
SLITRK2 SLIT and NTRK-like family, member 2 -3.09937
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -3.09568
RFX7 regulatory factor X, 7 -3.09163
FTL ferritin, light polypeptide -3.08688
CLDN5 claudin 5 -3.08574
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -3.07074
MTCL1 microtubule crosslinking factor 1 -3.07
VDAC3 voltage-dependent anion channel 3 -3.06733
GRSF1 G-rich RNA sequence binding factor 1 -3.06705
MCTP2 multiple C2 domains, transmembrane 2 -3.06533
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -3.06118
SEPTIN11 septin 11 -3.06118
USP34 ubiquitin specific peptidase 34 -3.05892
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -3.05601
CLDN16 claudin 16 -3.05192
RASL12 RAS-like, family 12 -3.04988
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.0477
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -3.04708
IER2 immediate early response 2 -3.04455
OR2W1 olfactory receptor, family 2, subfamily W, member 1 -3.04433
PTGES prostaglandin E synthase -3.04113
TUBB1 tubulin, beta 1 class VI -3.0397
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -3.03901
UQCRC1 ubiquinol-cytochrome c reductase core protein I -3.03853
SRP9 signal recognition particle 9kDa -3.03826
PROS1 protein S (alpha) -3.03642
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -3.03596
PROCR protein C receptor, endothelial -3.03528
TARBP2 TAR (HIV-1) RNA binding protein 2 -3.0332
APOBR apolipoprotein B receptor -3.0328
RFK riboflavin kinase -3.03091
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -3.02983
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.02898
RAB8B RAB8B, member RAS oncogene family -3.02213
GPR32 G protein-coupled receptor 32 -3.02176
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -3.02106
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa -3.02094
VPS9D1 VPS9 domain containing 1 -3.0192
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -3.01315
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -3.01138
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -3.0112
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -3.01106
INPP5D inositol polyphosphate-5-phosphatase, 145kDa -3.00441
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -3.00154