blindness Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

626 genes co-occuring with the disease blindness in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NDP Norrie disease (pseudoglioma) 1.92576
RHO rhodopsin 1.85273
RPE65 retinal pigment epithelium-specific protein 65kDa 1.84727
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.79165
CFH complement factor H 1.68136
VEGFA vascular endothelial growth factor A 1.65745
CRX cone-rod homeobox 1.6162
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.6162
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.58939
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.5282
MYO7A myosin VIIA 1.52248
CEP290 centrosomal protein 290kDa 1.47023
RPGR retinitis pigmentosa GTPase regulator 1.38428
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.36553
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.33894
WDR36 WD repeat domain 36 1.29877
NRL neural retina leucine zipper 1.27824
HTRA1 HtrA serine peptidase 1 1.27563
LCA5 Leber congenital amaurosis 5 1.26342
ALMS1 Alstrom syndrome protein 1 1.24037
OPTN optineurin 1.23907
LRP5 low density lipoprotein receptor-related protein 5 1.21435
INS insulin 1.2018
SRCIN1 SRC kinase signaling inhibitor 1 1.18927
TEX28 testis expressed 28 1.1793
TEX28P2 testis expressed 28 pseudogene 2 1.1793
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.17464
CLN3 ceroid-lipofuscinosis, neuronal 3 1.16821
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.1473
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 1.14517
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.13755
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.12572
CLN5 ceroid-lipofuscinosis, neuronal 5 1.12319
ATXN7 ataxin 7 1.11898
CRYAA crystallin, alpha A 1.08999
PPT1 palmitoyl-protein thioesterase 1 1.08789
PCDH15 protocadherin-related 15 1.0816
TULP1 tubby like protein 1 1.07782
OPN4 opsin 4 1.07236
CNGB3 cyclic nucleotide gated channel beta 3 1.06942
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 1.06942
CHM choroideremia (Rab escort protein 1) 1.05934
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.03788
AVPR2 arginine vasopressin receptor 2 1.03493
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.03198
CRYBB2 crystallin, beta B2 1.00794
RBP3 retinol binding protein 3, interstitial 0.988114
CDH23 cadherin-related 23 0.984321
CNGB1 cyclic nucleotide gated channel beta 1 0.97338
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.967502
NXNL2 nucleoredoxin-like 2 0.965405
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.962053
CNGA3 cyclic nucleotide gated channel alpha 3 0.960797
NXNL1 nucleoredoxin-like 1 0.954943
CD4 CD4 molecule 0.953273
FAM161A family with sequence similarity 161, member A 0.927105
SLC7A14 solute carrier family 7, member 14 0.90321
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 0.901978
TMCO1 transmembrane and coiled-coil domains 1 0.891308
CRYGC crystallin, gamma C 0.887208
TIMP3 TIMP metallopeptidase inhibitor 3 0.88516
ZNF469 zinc finger protein 469 0.872053
VSX2 visual system homeobox 2 0.870825
LAMA3 laminin, alpha 3 0.870825
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.870006
RCVRN recoverin 0.868777
CLUL1 clusterin-like 1 (retinal) 0.862637
DTHD1 death domain containing 1 0.858134
NUB1 negative regulator of ubiquitin-like proteins 1 0.856087
CRYBA1 crystallin, beta A1 0.85404
NPR1 natriuretic peptide receptor 1 0.852402
GUCY2C guanylate cyclase 2C 0.851583
CRYGD crystallin, gamma D 0.849126
FOXC1 forkhead box C1 0.830689
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.829049
SIX6 SIX homeobox 6 0.821257
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.806077
RILPL2 Rab interacting lysosomal protein-like 2 0.794591
KLHL23 kelch-like family member 23 0.794591
MTERF3 mitochondrial transcription termination factor 3 0.794591
RLBP1 retinaldehyde binding protein 1 0.792951
ZNF644 zinc finger protein 644 0.785165
TULP3 tubby like protein 3 0.782298
MRPL47 mitochondrial ribosomal protein L47 0.776568
RAB42 RAB42, member RAS oncogene family 0.776568
C12ORF56 chromosome 12 open reading frame 56 0.776568
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 0.776568
FZD4 frizzled class receptor 4 0.767985
LCN1 lipocalin 1 0.765535
MVB12B multivesicular body subunit 12B 0.765127
IQCB1 IQ motif containing B1 0.762678
PRCD progressive rod-cone degeneration 0.761047
LACE1 lactation elevated 1 0.754527
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.748017
CFB complement factor B 0.74761
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.743141
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.743141
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.732191
COMMD6 COMM domain containing 6 0.729762
C1QTNF9B C1q and tumor necrosis factor related protein 9B 0.721673
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.720058
ZC3H11A zinc finger CCCH-type containing 11A 0.716425
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.716021
IGF1 insulin-like growth factor 1 (somatomedin C) 0.714811
SRBD1 S1 RNA binding domain 1 0.714811
CERKL ceramide kinase-like 0.714005
ICAM1 intercellular adhesion molecule 1 0.707157
CRYGS crystallin, gamma S 0.70434
DTWD2 DTW domain containing 2 0.703536
PLIN2 perilipin 2 0.689492
UFSP2 UFM1-specific peptidase 2 0.687091
AFAP1 actin filament associated protein 1 0.677903
DFNB31 deafness, autosomal recessive 31 0.676308
TSPAN12 tetraspanin 12 0.671527
HMX3 H6 family homeobox 3 0.655254
ELOVL4 ELOVL fatty acid elongase 4 0.652089
CPNE1 copine I 0.651298
AQP4 aquaporin 4 0.648928
C2ORF71 chromosome 2 open reading frame 71 0.646165
BBS5 Bardet-Biedl syndrome 5 0.645375
PRIMPOL primase and polymerase (DNA-directed) 0.643797
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 0.643797
FGF2 fibroblast growth factor 2 (basic) 0.641433
XG Xg blood group 0.640926
C2 complement component 2 0.640645
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.640251
C3 complement component 3 0.633563
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.631205
PRDM5 PR domain containing 5 0.626888
FYCO1 FYVE and coiled-coil domain containing 1 0.626103
TJP1 tight junction protein 1 0.626103
DMXL1 Dmx-like 1 0.622967
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.61866
KERA keratocan 0.61866
PAX6 paired box 6 0.61866
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.613574
UBA6 ubiquitin-like modifier activating enzyme 6 0.613183
PPP1R17 protein phosphatase 1, regulatory subunit 17 0.610448
HSF4 heat shock transcription factor 4 0.609276
OPA1 optic atrophy 1 (autosomal dominant) 0.608885
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.60303
ACBD5 acyl-CoA binding domain containing 5 0.59952
OSTM1 osteopetrosis associated transmembrane protein 1 0.598351
CNTF ciliary neurotrophic factor 0.596012
GFAP glial fibrillary acidic protein 0.592506
SH3BP4 SH3-domain binding protein 4 0.592116
CCL2 chemokine (C-C motif) ligand 2 0.587054
RAB8A RAB8A, member RAS oncogene family 0.581996
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.578106
CRYBB3 crystallin, beta B3 0.577716
ST18 suppression of tumorigenicity 18, zinc finger 0.577327
SOD2 superoxide dismutase 2, mitochondrial 0.575383
PARL presenilin associated, rhomboid-like 0.574994
MYO6 myosin VI 0.573828
COL8A2 collagen, type VIII, alpha 2 0.571495
CTGF connective tissue growth factor 0.569941
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.567997
MAOA monoamine oxidase A 0.567997
CRYBB1 crystallin, beta B1 0.565666
ADGRV1 adhesion G protein-coupled receptor V1 0.564889
CCDC101 coiled-coil domain containing 101 0.561781
RBP7 retinol binding protein 7, cellular 0.561781
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 0.559839
COL11A1 collagen, type XI, alpha 1 0.551298
TGFB1 transforming growth factor, beta 1 0.549747
CTSD cathepsin D 0.549747
NES nestin 0.547807
SYT5 synaptotagmin V 0.544705
ARL4C ADP-ribosylation factor-like 4C 0.541217
PITX2 paired-like homeodomain 2 0.539667
MERTK MER proto-oncogene, tyrosine kinase 0.538893
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 0.537344
CISD2 CDGSH iron sulfur domain 2 0.535409
ASB10 ankyrin repeat and SOCS box containing 10 0.533475
MLPH melanophilin 0.531928
LUM lumican 0.531541
TBKBP1 TBK1 binding protein 1 0.526132
GUCA1A guanylate cyclase activator 1A (retina) 0.524974
PRELP proline/arginine-rich end leucine-rich repeat protein 0.521502
PRPF31 pre-mRNA processing factor 31 0.521117
RBM10 RNA binding motif protein 10 0.520731
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.512648
GRK1 G protein-coupled receptor kinase 1 0.510344
ACE angiotensin I converting enzyme 0.509576
CNTLN centlein, centrosomal protein 0.509192
ERAS ES cell expressed Ras 0.508041
DNAH8 dynein, axonemal, heavy chain 8 0.507657
ISL2 ISL LIM homeobox 2 0.507657
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.505356
COL18A1 collagen, type XVIII, alpha 1 0.503058
HNMT histamine N-methyltransferase 0.503058
PEX19 peroxisomal biogenesis factor 19 0.501909
CAPN5 calpain 5 0.501527
HACL1 2-hydroxyacyl-CoA lyase 1 0.499997
RFTN1 raftlin, lipid raft linker 1 0.499997
EXOC6 exocyst complex component 6 0.499231
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 0.497703
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.495793
BEST2 bestrophin 2 0.49274
TNF tumor necrosis factor 0.492359
ALB albumin 0.492359
TUB tubby bipartite transcription factor 0.491597
COCH cochlin 0.48893
CNOT3 CCR4-NOT transcription complex, subunit 3 0.488549
ABLIM1 actin binding LIM protein 1 0.483985
MMP9 matrix metallopeptidase 9 0.480186
RAX retina and anterior neural fold homeobox 0.478668
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.476772
TTC8 tetratricopeptide repeat domain 8 0.474877
OAT ornithine aminotransferase 0.474498
CLCN3 chloride channel, voltage-sensitive 3 0.47374
RIPK3 receptor-interacting serine-threonine kinase 3 0.471089
GALM galactose mutarotase (aldose 1-epimerase) 0.470711
MMP1 matrix metallopeptidase 1 0.470332
GTF3A general transcription factor IIIA 0.468441
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.463149
ADGRA3 adhesion G protein-coupled receptor A3 0.462394
DCX doublecortin 0.458241
GPX1 glutathione peroxidase 1 0.455978
BTBD3 BTB (POZ) domain containing 3 0.455601
CRP C-reactive protein, pentraxin-related 0.450701
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.449571
FLT1 fms-related tyrosine kinase 1 0.449571
FASLG Fas ligand (TNF superfamily, member 6) 0.449194
PITPNM3 PITPNM family member 3 0.448441
TMEM114 transmembrane protein 114 0.447687
NOA1 nitric oxide associated 1 0.446182
TPP1 tripeptidyl peptidase I 0.445805
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.439034
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.436402
MKKS McKusick-Kaufman syndrome 0.433772
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.433772
THBS1 thrombospondin 1 0.43227
BBS4 Bardet-Biedl syndrome 4 0.43227
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.43227
MUSTN1 musculoskeletal, embryonic nuclear protein 1 0.430017
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.429642
IL27 interleukin 27 0.428891
BDNF brain-derived neurotrophic factor 0.42814
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.42739
DICER1 dicer 1, ribonuclease type III 0.42589
CD79A CD79a molecule, immunoglobulin-associated alpha 0.425514
IMPG2 interphotoreceptor matrix proteoglycan 2 0.425514
BFSP2 beaded filament structural protein 2, phakinin 0.424765
HLA-B major histocompatibility complex, class I, B 0.422515
BIRC6 baculoviral IAP repeat containing 6 0.42214
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.42139
SLC39A5 solute carrier family 39 (zinc transporter), member 5 0.420641
SKAP2 src kinase associated phosphoprotein 2 0.420266
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.420266
BLID BH3-like motif containing, cell death inducer 0.418768
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.418019
ALG12 ALG12, alpha-1,6-mannosyltransferase 0.416147
SST somatostatin 0.416147
EYS eyes shut homolog (Drosophila) 0.415398
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.415398
B3GAT3 beta-1,3-glucuronyltransferase 3 0.413527
XPOT exportin, tRNA 0.413527
LDB2 LIM domain binding 2 0.412779
PRPF4 pre-mRNA processing factor 4 0.412031
ADAM9 ADAM metallopeptidase domain 9 0.411657
PDZD7 PDZ domain containing 7 0.411283
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.410535
PITX3 paired-like homeodomain 3 0.408292
CAPZB capping protein (actin filament) muscle Z-line, beta 0.408292
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.405678
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.404931
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.403811
SAG S-antigen; retina and pineal gland (arrestin) 0.401945
EMC3 ER membrane protein complex subunit 3 0.400453
GPX5 glutathione peroxidase 5 0.400453
PDIA5 protein disulfide isomerase family A, member 5 0.398962
IL17RC interleukin 17 receptor C 0.398216
GPX4 glutathione peroxidase 4 0.397098
BMP4 bone morphogenetic protein 4 0.39598
MXD3 MAX dimerization protein 3 0.394863
KRT12 keratin 12, type I 0.394118
NF1 neurofibromin 1 0.392629
EMILIN2 elastin microfibril interfacer 2 0.392629
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.391885
FN1 fibronectin 1 0.389281
SYP synaptophysin 0.388166
MMP2 matrix metallopeptidase 2 0.388166
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.388166
ANGPTL7 angiopoietin-like 7 0.387423
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.387423
NINL ninein-like 0.384451
IFT88 intraflagellar transport 88 0.384079
MNX1 motor neuron and pancreas homeobox 1 0.383708
PEX10 peroxisomal biogenesis factor 10 0.37555
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 0.370368
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.369997
MEGF6 multiple EGF-like-domains 6 0.369628
ADCY10 adenylate cyclase 10 (soluble) 0.369628
PRPF6 pre-mRNA processing factor 6 0.368888
SIX3 SIX homeobox 3 0.368149
FILIP1L filamin A interacting protein 1-like 0.367779
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) 0.367779
GJD2 gap junction protein, delta 2, 36kDa 0.36741
CCR2 chemokine (C-C motif) receptor 2 0.36704
PLBD2 phospholipase B domain containing 2 0.366301
PARD6A par-6 family cell polarity regulator alpha 0.366301
EMCN endomucin 0.365932
CAV2 caveolin 2 0.359289
SUCNR1 succinate receptor 1 0.357446
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.356341
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.353763
PTGDR prostaglandin D2 receptor (DP) 0.353395
CAT catalase 0.353027
PEX5 peroxisomal biogenesis factor 5 0.35082
AANAT aralkylamine N-acetyltransferase 0.350084
PRR4 proline rich 4 (lacrimal) 0.350084
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 0.347511
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.346777
MARK3 MAP/microtubule affinity-regulating kinase 3 0.345675
GDNF glial cell derived neurotrophic factor 0.345308
DCLK1 doublecortin-like kinase 1 0.344207
IGF2-AS IGF2 antisense RNA 0.344207
KIFC3 kinesin family member C3 0.343473
MYO10 myosin X 0.340906
GLUL glutamate-ammonia ligase 0.340906
SNX10 sorting nexin 10 0.340539
ZBTB14 zinc finger and BTB domain containing 14 0.340173
TMEM126A transmembrane protein 126A 0.339806
TGFB2 transforming growth factor, beta 2 0.338707
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.337975
CPT1C carnitine palmitoyltransferase 1C 0.33651
USP9X ubiquitin specific peptidase 9, X-linked 0.335778
MYOM1 myomesin 1 0.335046
TIMP1 TIMP metallopeptidase inhibitor 1 0.335046
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.333949
MEF2C myocyte enhancer factor 2C 0.331756
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.331025
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.33066
EPHA2 EPH receptor A2 0.329565
RAB1A RAB1A, member RAS oncogene family 0.328834
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.328469
TSPO translocator protein (18kDa) 0.328469
PITX1 paired-like homeodomain 1 0.32774
RSAD2 radical S-adenosyl methionine domain containing 2 0.326646
PDC phosducin 0.325916
NLRX1 NLR family member X1 0.325916
HMOX2 heme oxygenase 2 0.325552
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.324458
LACRT lacritin 0.324458
ANGPT2 angiopoietin 2 0.322637
COL15A1 collagen, type XV, alpha 1 0.321909
PLCB4 phospholipase C, beta 4 0.320817
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.319363
LIG3 ligase III, DNA, ATP-dependent 0.318635
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 0.317909
NR2E1 nuclear receptor subfamily 2, group E, member 1 0.317545
NPHP4 nephronophthisis 4 0.314278
IL15RA interleukin 15 receptor, alpha 0.314278
TAS2R38 taste receptor, type 2, member 38 0.313915
GJA3 gap junction protein, alpha 3, 46kDa 0.313915
CFHR3 complement factor H-related 3 0.313552
SAP30 Sin3A-associated protein, 30kDa 0.313189
LTBP2 latent transforming growth factor beta binding protein 2 0.312102
PGF placental growth factor 0.310652
PRPH2 peripherin 2 (retinal degeneration, slow) 0.308118
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.308118
PLCB2 phospholipase C, beta 2 0.308118
COTL1 coactosin-like F-actin binding protein 1 0.307757
TGFBI transforming growth factor, beta-induced, 68kDa 0.307033
TSTA3 tissue specific transplantation antigen P35B 0.30631
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.305226
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.305226
HSPG2 heparan sulfate proteoglycan 2 0.304142
IMPG1 interphotoreceptor matrix proteoglycan 1 0.301615
MIP major intrinsic protein of lens fiber 0.301615
KDR kinase insert domain receptor 0.301615
TLR4 toll-like receptor 4 0.301254
TNNT1 troponin T type 1 (skeletal, slow) 0.298371
LPAR3 lysophosphatidic acid receptor 3 0.296931
MIPEP mitochondrial intermediate peptidase 0.296931
CRYBA2 crystallin, beta A2 0.296931
ANO1 anoctamin 1, calcium activated chloride channel 0.295851
CHML choroideremia-like (Rab escort protein 2) 0.294772
TXN thioredoxin 0.290462
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.290103
HBA1 hemoglobin, alpha 1 0.290103
MYO5A myosin VA (heavy chain 12, myoxin) 0.288668
PPARG peroxisome proliferator-activated receptor gamma 0.287593
LYPLAL1 lysophospholipase-like 1 0.287593
ELOVL1 ELOVL fatty acid elongase 1 0.284728
GCLM glutamate-cysteine ligase, modifier subunit 0.283655
NF2 neurofibromin 2 (merlin) 0.281153
APOE apolipoprotein E 0.280796
POU4F1 POU class 4 homeobox 1 0.280796
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.280082
MFN1 mitofusin 1 0.279724
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.279011
UBIAD1 UbiA prenyltransferase domain containing 1 0.278297
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.27687
CRYGB crystallin, gamma B 0.276158
EFNA4 ephrin-A4 0.275089
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.274732
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.274376
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.274021
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.273664
COL2A1 collagen, type II, alpha 1 0.272953
GLUD2 glutamate dehydrogenase 2 0.272597
LOXL1 lysyl oxidase-like 1 0.272597
FCHSD2 FCH and double SH3 domains 2 0.270464
ZFYVE1 zinc finger, FYVE domain containing 1 0.270108
HBA2 hemoglobin, alpha 2 0.269398
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.267622
GJA8 gap junction protein, alpha 8, 50kDa 0.266558
DOCK5 dedicator of cytokinesis 5 0.26514
CA4 carbonic anhydrase IV 0.264785
SZRD1 SUZ RNA binding domain containing 1 0.264431
SRSF9 serine/arginine-rich splicing factor 9 0.264077
HLX H2.0-like homeobox 0.264077
DOCK2 dedicator of cytokinesis 2 0.263368
CLEC6A C-type lectin domain family 6, member A 0.261952
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.260538
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.257358
CAST calpastatin 0.255946
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.255594
WDR19 WD repeat domain 19 0.255241
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.254536
VRK2 vaccinia related kinase 2 0.254536
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.253479
COL11A2 collagen, type XI, alpha 2 0.253479
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 0.25207
ADORA3 adenosine A3 receptor 0.250663
USH1G Usher syndrome 1G (autosomal recessive) 0.248905
DNASE1L1 deoxyribonuclease I-like 1 0.248203
WTAP Wilms tumor 1 associated protein 0.246098
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.245396
SLC38A5 solute carrier family 38, member 5 0.244696
CRYAB crystallin, alpha B 0.244696
FAM120A family with sequence similarity 120A 0.243995
CXCL9 chemokine (C-X-C motif) ligand 9 0.243295
GSTM5 glutathione S-transferase mu 5 0.241546
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.240497
LAMA1 laminin, alpha 1 0.240497
SAE1 SUMO1 activating enzyme subunit 1 0.239899
RBMS1 RNA binding motif, single stranded interacting protein 1 0.238054
MBP myelin basic protein 0.237009
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.23666
GPNMB glycoprotein (transmembrane) nmb 0.236312
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.236312
WNT8B wingless-type MMTV integration site family, member 8B 0.235616
B3GALTL beta 1,3-galactosyltransferase-like 0.23353
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.232836
VSX1 visual system homeobox 1 0.231102
INADL InaD-like (Drosophila) 0.22937
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.226607
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.226262
MAOB monoamine oxidase B 0.225917
TCERG1 transcription elongation regulator 1 0.225573
LGALS9 lectin, galactoside-binding, soluble, 9 0.225229
BSG basigin (Ok blood group) 0.223509
TBC1D4 TBC1 domain family, member 4 0.222822
MFSD8 major facilitator superfamily domain containing 8 0.22145
GLP1R glucagon-like peptide 1 receptor 0.220424
CLDN5 claudin 5 0.219398
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.217012
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.216672
NGB neuroglobin 0.216332
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.215314
JCHAIN joining chain of multimeric IgA and IgM 0.214975
TBK1 TANK-binding kinase 1 0.214636
TNP1 transition protein 1 (during histone to protamine replacement) 0.213621
LY96 lymphocyte antigen 96 0.213621
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.213283
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.212945
THY1 Thy-1 cell surface antigen 0.211934
SALL2 spalt-like transcription factor 2 0.211597
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 0.211261
RAB27B RAB27B, member RAS oncogene family 0.211261
GUCA2A guanylate cyclase activator 2A (guanylin) 0.211261
MSN moesin 0.210925
BEND3 BEN domain containing 3 0.210589
GALK1 galactokinase 1 0.210253
CST1 cystatin SN 0.207245
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.205916
FES FES proto-oncogene, tyrosine kinase 0.205916
ANGPT1 angiopoietin 1 0.205916
CST4 cystatin S 0.205585
IL18 interleukin 18 0.204923
IL1B interleukin 1, beta 0.204263
PRKCQ protein kinase C, theta 0.204263
CFHR1 complement factor H-related 1 0.203933
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.203275
FBXO11 F-box protein 11 0.203275
BBS2 Bardet-Biedl syndrome 2 0.202946
DOCK4 dedicator of cytokinesis 4 0.200656
LGALS1 lectin, galactoside-binding, soluble, 1 0.200331
ASGR1 asialoglycoprotein receptor 1 0.200331
NGF nerve growth factor (beta polypeptide) 0.199033
NOTCH1 notch 1 0.198709
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.198386
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.196779
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.196139
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.19582
OTX2 orthodenticle homeobox 2 0.19582
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.195501
ATOH7 atonal homolog 7 (Drosophila) 0.195501
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.195183
C5AR1 complement component 5a receptor 1 0.194232
PRAMEF12 PRAME family member 12 0.1936
XK X-linked Kx blood group 0.1936
MEIS2 Meis homeobox 2 0.1936
UNC119 unc-119 homolog (C. elegans) 0.192031
ANXA5 annexin A5 0.191719
RAB27A RAB27A, member RAS oncogene family 0.191097
NOL9 nucleolar protein 9 0.190786
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.190786
PROM1 prominin 1 0.190168
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.189551
COL4A1 collagen, type IV, alpha 1 0.188022
HLA-C major histocompatibility complex, class I, C 0.187719
NCK1 NCK adaptor protein 1 0.187719
GMDS GDP-mannose 4,6-dehydratase 0.187113
GCG glucagon 0.187113
CLRN1 clarin 1 0.18651
BBS1 Bardet-Biedl syndrome 1 0.18651
MYO15A myosin XVA 0.18591
GJA1 gap junction protein, alpha 1, 43kDa 0.185313
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.184424
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.183835
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 0.182168
CISD1 CDGSH iron sulfur domain 1 0.178403
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.178126
MYL12B myosin, light chain 12B, regulatory 0.176757
LHX2 LIM homeobox 2 0.176485
SEPT7 septin 7 0.175411
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.174881
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.174354
SRSF5 serine/arginine-rich splicing factor 5 0.172799
BMP8B bone morphogenetic protein 8b 0.172327
ENO2 enolase 2 (gamma, neuronal) 0.172291
RDH8 retinol dehydrogenase 8 (all-trans) 0.171785
COL8A1 collagen, type VIII, alpha 1 0.170789
TF transferrin 0.167682
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.167682
OCLN occludin 0.167682
CXCL10 chemokine (C-X-C motif) ligand 10 0.167224
DNTT DNA nucleotidylexotransferase 0.167224
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.166768
SEC63 SEC63 homolog (S. cerevisiae) 0.165874
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.165874
LIMK2 LIM domain kinase 2 0.165435
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.164571
SIX1 SIX homeobox 1 0.164359
RAB11A RAB11A, member RAS oncogene family 0.164359
PRG1 p53-responsive gene 1 0.164149
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.164149
GSTA3 glutathione S-transferase alpha 3 0.163523
PAX2 paired box 2 0.163317
ITGAD integrin, alpha D 0.163111
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.162908
MVK mevalonate kinase 0.162908
CD59 CD59 molecule, complement regulatory protein 0.162109
M6PR mannose-6-phosphate receptor (cation dependent) 0.160761
CERK ceramide kinase 0.160574
UBC ubiquitin C 0.160387
PXDN peroxidasin 0.160021
OCRL oculocerebrorenal syndrome of Lowe 0.159658
NYX nyctalopin 0.159
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.158951
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 0.158778
GAS7 growth arrest-specific 7 0.158266
VLDLR very low density lipoprotein receptor 0.157929
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.149633
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.14855
RORC RAR-related orphan receptor C 0.148255
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.14569
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.145339
BACE1 beta-site APP-cleaving enzyme 1 0.145044
GK glycerol kinase 0.144527
AIF1 allograft inflammatory factor 1 0.143709
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.143247
G6PD glucose-6-phosphate dehydrogenase 0.14316
PDE5A phosphodiesterase 5A, cGMP-specific 0.142467
SLC38A8 solute carrier family 38, member 8 0.142256
SOX3 SRY (sex determining region Y)-box 3 0.141389
FRMD7 FERM domain containing 7 0.141233
F9 coagulation factor IX 0.141011
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.140852
F8 coagulation factor VIII, procoagulant component 0.140016
KIAA1109 KIAA1109 0.139559
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.139499
MXD4 MAX dimerization protein 4 0.139481
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 0.139355
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.139289
RGR retinal G protein coupled receptor 0.139149
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.13811
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.13675
ARR3 arrestin 3, retinal (X-arrestin) 0.136473
PROKR2 prokineticin receptor 2 0.13587
OSCAR osteoclast associated, immunoglobulin-like receptor 0.135551
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.135427
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.135252
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.135184
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.134809
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.133998
PROK2 prokineticin 2 0.133527
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.133212
RD3 retinal degeneration 3 0.132563
CHD7 chromodomain helicase DNA binding protein 7 0.132552
MFRP membrane frizzled-related protein 0.132084
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.131633
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.13138
HRH2 histamine receptor H2 0.130855
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.130828
FGF8 fibroblast growth factor 8 (androgen-induced) 0.129738
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.128893
ENDOG endonuclease G 0.128569
ANOS1 anosmin 1 0.128153
DRD4 dopamine receptor D4 0.127078
GLB1 galactosidase, beta 1 0.126459
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.125794
ALLC allantoicase 0.125114
TES testin LIM domain protein 0.12458
GC group-specific component (vitamin D binding protein) 0.124297
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.123893
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.116283
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.114126
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.110022
CBS cystathionine-beta-synthase 0.104954
CASR calcium-sensing receptor 0.104723
FGFR1 fibroblast growth factor receptor 1 0.102245