blm Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Bloom syndrome, RecQ helicase-like|The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 641)
Similar Terms
Downloads & Tools

Genes

57 genes co-occuring with the biological term blm in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK1 cyclin-dependent kinase 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CLDN3 claudin 3
CLDN4 claudin 4
DNA2 DNA replication helicase/nuclease 2
ERCC6L excision repair cross-complementation group 6-like
EXO1 exonuclease 1
FANCC Fanconi anemia, complementation group C
FEN1 flap structure-specific endonuclease 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
LIG4 ligase IV, DNA, ATP-dependent
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH6 mutS homolog 6
MUS81 MUS81 structure-specific endonuclease subunit
MYH10 myosin, heavy chain 10, non-muscle
NBN nibrin
PML promyelocytic leukemia
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POT1 protection of telomeres 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RECQL RecQ helicase-like
RECQL4 RecQ protein-like 4
RECQL5 RecQ protein-like 5
RIF1 replication timing regulatory factor 1
RMI1 RecQ mediated genome instability 1
RMI2 RecQ mediated genome instability 2
RPA1 replication protein A1, 70kDa
SIRT1 sirtuin 1
SLX4 SLX4 structure-specific endonuclease subunit
SPIDR scaffolding protein involved in DNA repair
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TEP1 telomerase-associated protein 1
TERF2 telomeric repeat binding factor 2
TOP1MT topoisomerase (DNA) I, mitochondrial
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP3A topoisomerase (DNA) III alpha
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TTK TTK protein kinase
WRN Werner syndrome, RecQ helicase-like