bloc-1 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins. (Gene Ontology, GO_0031083)
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Genes

22 proteins co-occuring with the bloc-1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FAM91A1 family with sequence similarity 91, member A1 1.91604
DTNBP1 dystrobrevin binding protein 1 1.53218
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.49267
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 1.42486
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 1.22932
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 1.21066
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 1.16645
SNAPIN SNAP-associated protein 1.14034
HPS1 Hermansky-Pudlak syndrome 1 1.11429
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.11327
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.05892
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 1.02679
HPS4 Hermansky-Pudlak syndrome 4 0.964549
HPS3 Hermansky-Pudlak syndrome 3 0.933601
WASH7P WAS protein family homolog 7 pseudogene 0.762252
WASH6P WAS protein family homolog 6 pseudogene 0.758161
WASH1 WAS protein family homolog 1 0.755437
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.658619
TYRP1 tyrosinase-related protein 1 0.541529
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.529618
LAMP1 lysosomal-associated membrane protein 1 0.485289
CNTLN centlein, centrosomal protein 0.455214