bloom syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_2717)
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Genes

102 genes co-occuring with the disease bloom syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BLM Bloom syndrome, RecQ helicase-like 2.79109
WRN Werner syndrome, RecQ helicase-like 2.37008
RECQL RecQ helicase-like 2.09383
RMI1 RecQ mediated genome instability 1 1.96239
RECQL5 RecQ protein-like 5 1.95347
RECQL4 RecQ protein-like 4 1.9436
RMI2 RecQ mediated genome instability 2 1.83636
MUS81 MUS81 structure-specific endonuclease subunit 1.69815
RAD51 RAD51 recombinase 1.62605
TOP3A topoisomerase (DNA) III alpha 1.31843
SPIDR scaffolding protein involved in DNA repair 1.23386
GEN1 GEN1 Holliday junction 5' flap endonuclease 1.21695
FANCM Fanconi anemia, complementation group M 1.20742
RAD54L RAD54-like (S. cerevisiae) 1.1507
LIG1 ligase I, DNA, ATP-dependent 1.14475
SMC5 structural maintenance of chromosomes 5 1.1312
EME1 essential meiotic structure-specific endonuclease 1 1.10132
ATM ATM serine/threonine kinase 1.06648
SLX4 SLX4 structure-specific endonuclease subunit 1.02271
TREX2 three prime repair exonuclease 2 1.01638
RAD52 RAD52 homolog (S. cerevisiae) 0.990222
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.975903
RAD17 RAD17 homolog (S. pombe) 0.962472
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.942027
FANCD2 Fanconi anemia, complementation group D2 0.882292
H2AFX H2A histone family, member X 0.878605
RAD51D RAD51 paralog D 0.872872
FEN1 flap structure-specific endonuclease 1 0.872872
POT1 protection of telomeres 1 0.871234
ERCC2 excision repair cross-complementation group 2 0.866321
BSX brain-specific homeobox 0.831099
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.757378
FANCI Fanconi anemia, complementation group I 0.750457
BRCA1 breast cancer 1, early onset 0.75005
CAMKV CaM kinase-like vesicle-associated 0.736243
PML promyelocytic leukemia 0.728952
MSH4 mutS homolog 4 0.725716
BRCA2 breast cancer 2, early onset 0.72127
PKM pyruvate kinase, muscle 0.720461
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.712392
LIG3 ligase III, DNA, ATP-dependent 0.710378
UNG uracil-DNA glycosylase 0.681495
MCM8 minichromosome maintenance complex component 8 0.680697
TP53 tumor protein p53 0.680297
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.664372
RFXANK regulatory factor X-associated ankyrin-containing protein 0.63907
DNA2 DNA replication helicase/nuclease 2 0.616312
CDC7 cell division cycle 7 0.591727
WRNIP1 Werner helicase interacting protein 1 0.591727
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.576161
RAD18 RAD18 E3 ubiquitin protein ligase 0.575772
TOPBP1 topoisomerase (DNA) II binding protein 1 0.575383
MSH5 mutS homolog 5 0.57305
UBE2N ubiquitin-conjugating enzyme E2N 0.571495
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.559839
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 0.55945
FANCC Fanconi anemia, complementation group C 0.549359
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.54393
SUMO1 small ubiquitin-like modifier 1 0.539667
GPR148 G protein-coupled receptor 148 0.532701
SUMO3 small ubiquitin-like modifier 3 0.528063
FERMT1 fermitin family member 1 0.526904
ERCC6 excision repair cross-complementation group 6 0.520346
OPHN1 oligophrenin 1 0.51534
C1QBP complement component 1, q subcomponent binding protein 0.511496
SUMO2 small ubiquitin-like modifier 2 0.510728
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.507273
ERCC3 excision repair cross-complementation group 3 0.503058
CDA cytidine deaminase 0.484744
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.476014
TOP2B topoisomerase (DNA) II beta 180kDa 0.472982
FANCA Fanconi anemia, complementation group A 0.461261
EYA1 EYA transcriptional coactivator and phosphatase 1 0.420641
PLK2 polo-like kinase 2 0.401572
PCNA proliferating cell nuclear antigen 0.368149
MSH3 mutS homolog 3 0.367779
FANCF Fanconi anemia, complementation group F 0.362239
CHEK1 checkpoint kinase 1 0.351923
DDB1 damage-specific DNA binding protein 1, 127kDa 0.350452
DAXX death-domain associated protein 0.349349
TOP1 topoisomerase (DNA) I 0.3292
DNAH8 dynein, axonemal, heavy chain 8 0.304503
NBN nibrin 0.299812
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.275445
SP100 SP100 nuclear antigen 0.271886
MCOLN1 mucolipin 1 0.269398
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.267267
LIG4 ligase IV, DNA, ATP-dependent 0.259477
NUCLEOLIN nucleolin multifunctional protein 0.256652
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.251366
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.251015
APEH acylaminoacyl-peptide hydrolase 0.241895
DLK1 delta-like 1 homolog (Drosophila) 0.232142
APRT adenine phosphoribosyltransferase 0.221108
ERCC4 excision repair cross-complementation group 4 0.198386
RAD50 RAD50 homolog (S. cerevisiae) 0.196459
E2F3 E2F transcription factor 3 0.188022
CDC25C cell division cycle 25C 0.18651
ATR ATR serine/threonine kinase 0.16933
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.165435
ERCC5 excision repair cross-complementation group 5 0.161912
COX5A cytochrome c oxidase subunit Va 0.159658