bmi Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention) (Experimental Factor Ontology, EFO_0004340)
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Genes

212 genes co-occuring with the biological term bmi in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGRP agouti related neuropeptide
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSG alpha-2-HS-glycoprotein
AIF1 allograft inflammatory factor 1
AMH anti-Mullerian hormone
ANKH ANKH inorganic pyrophosphate transport regulator
APLN apelin
APLNR apelin receptor
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASIP agouti signaling protein
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4ORF32 chromosome 4 open reading frame 32
CAPN10 calpain 10
CASR calcium-sensing receptor
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD247 CD247 molecule
CD68 CD68 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
COPA coatomer protein complex, subunit alpha
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DIO2 deiodinase, iodothyronine, type II
DPP4 dipeptidyl-peptidase 4
DRD4 dopamine receptor D4
ENO2 enolase 2 (gamma, neuronal)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FABP4 fatty acid binding protein 4, adipocyte
FAIM2 Fas apoptotic inhibitory molecule 2
FGA fibrinogen alpha chain
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FNDC5 fibronectin type III domain containing 5
FOXA2 forkhead box A2
FTO fat mass and obesity associated
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCG glucagon
GGT1 gamma-glutamyltransferase 1
GGT2 gamma-glutamyltransferase 2
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIP gastric inhibitory polypeptide
GLP1R glucagon-like peptide 1 receptor
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HHEX hematopoietically expressed homeobox
HLA-C major histocompatibility complex, class I, C
HMGA2 high mobility group AT-hook 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IAPP islet amyloid polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
IL33 interleukin 33
IL4R interleukin 4 receptor
IL6 interleukin 6
INS insulin
INSIG2 insulin induced gene 2
IRS1 insulin receptor substrate 1
ITLN1 intelectin 1 (galactofuranose binding)
KCNK9 potassium channel, two pore domain subfamily K, member 9
KLK3 kallikrein-related peptidase 3
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
LCT lactase
LEP leptin
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LHB luteinizing hormone beta polypeptide
LIN28B lin-28 homolog B (C. elegans)
LIPC lipase, hepatic
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAOA monoamine oxidase A
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP2K5 mitogen-activated protein kinase kinase 5
MC4R melanocortin 4 receptor
MGLL monoglyceride lipase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MLH1 mutL homolog 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1B melatonin receptor 1B
MTTP microsomal triglyceride transfer protein
NAMPT nicotinamide phosphoribosyltransferase
NEUROG3 neurogenin 3
NNT nicotinamide nucleotide transhydrogenase
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPY5R neuropeptide Y receptor Y5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
OGG1 8-oxoguanine DNA glycosylase
OXTR oxytocin receptor
PEPD peptidase D
PF4 platelet factor 4
PGR progesterone receptor
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRDX3 peroxiredoxin 3
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRL prolactin
PTGES2 prostaglandin E synthase 2
PYY peptide YY
RAD51B RAD51 paralog B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RETN resistin
RLN1 relaxin 1
RPL21P7 ribosomal protein L21 pseudogene 7
SDC1 syndecan 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCZ sarcoglycan, zeta
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOCS3 suppressor of cytokine signaling 3
SOST sclerostin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK33 serine/threonine kinase 33
STS steroid sulfatase (microsomal), isozyme S
TAS2R38 taste receptor, type 2, member 38
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TF transferrin
TFRC transferrin receptor
TGFBI transforming growth factor, beta-induced, 68kDa
THADA thyroid adenoma associated
TMEM18 transmembrane protein 18
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USF1 upstream transcription factor 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WNT10B wingless-type MMTV integration site family, member 10B