bortezomib Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

81 genes co-occuring with the biological term bortezomib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA2 annexin A2
APOC1 apolipoprotein C-I
ATF4 activating transcription factor 4
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC7 baculoviral IAP repeat containing 7
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD34 CD34 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFLAR CASP8 and FADD-like apoptosis regulator
CKS1B CDC28 protein kinase regulatory subunit 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR3 chemokine (C-X-C motif) receptor 3
DICER1 dicer 1, ribonuclease type III
E2F1 E2F transcription factor 1
ESR1 estrogen receptor 1
FGFR3 fibroblast growth factor receptor 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
IL6 interleukin 6
IRF4 interferon regulatory factor 4
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIAA1524 KIAA1524
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR15A microRNA 15a
MIR187 microRNA 187
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRDM1 PR domain containing 1, with ZNF domain
PRKCD protein kinase C, delta
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RRAD Ras-related associated with diabetes
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIGAR TP53 induced glycolysis regulatory phosphatase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRAF3 TNF receptor-associated factor 3
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase