botulism Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F) located_in neuromuscular junction, resulting in descending muscle paralysis, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F. (Human Disease Ontology, DOID_11976)
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Genes

74 genes co-occuring with the disease botulism in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SYT2 synaptotagmin II 2.24364
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.15716
NSF N-ethylmaleimide-sensitive factor 1.87469
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.77631
SNAP23 synaptosomal-associated protein, 23kDa 1.77225
HCFC2 host cell factor C2 1.43157
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.38297
TSN translin 1.35333
CRTAC1 cartilage acidic protein 1 1.22605
SV2C synaptic vesicle glycoprotein 2C 1.07782
ZMPSTE24 zinc metallopeptidase STE24 1.0753
C1D C1D nuclear receptor corepressor 1.07488
FBXW2 F-box and WD repeat domain containing 2 1.06942
SYT1 synaptotagmin I 1.00625
STX1A syntaxin 1A (brain) 0.977165
SMAD9 SMAD family member 9 0.888848
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.879014
HAS1 hyaluronan synthase 1 0.860999
ALLC allantoicase 0.851583
IGHV3-30 immunoglobulin heavy variable 3-30 0.814283
TECR trans-2,3-enoyl-CoA reductase 0.808949
STX1B syntaxin 1B 0.804436
MTO1 mitochondrial tRNA translation optimization 1 0.802795
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 0.777386
VAMP3 vesicle-associated membrane protein 3 0.699116
CHAD chondroadherin 0.697911
ANGPTL7 angiopoietin-like 7 0.695103
STX4 syntaxin 4 0.690293
COIL coilin 0.689092
SNAP25 synaptosomal-associated protein, 25kDa 0.688291
LY96 lymphocyte antigen 96 0.660404
RARA retinoic acid receptor, alpha 0.637495
CLEC3A C-type lectin domain family 3, member A 0.637495
PATE1 prostate and testis expressed 1 0.636315
PRDX5 peroxiredoxin 5 0.633956
CLEC2B C-type lectin domain family 2, member B 0.631991
STXBP1 syntaxin binding protein 1 0.628457
DYNLRB1 dynein, light chain, roadblock-type 1 0.614747
CLEC10A C-type lectin domain family 10, member A 0.607714
NAGA N-acetylgalactosaminidase, alpha- 0.557509
PAX3 paired box 3 0.552463
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.542767
PAX4 paired box 4 0.531541
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.530381
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.525746
YME1L1 YME1-like 1 ATPase 0.524588
MUSK muscle, skeletal, receptor tyrosine kinase 0.524202
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.521502
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.518805
FXYD1 FXYD domain containing ion transport regulator 1 0.505739
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.499997
GFER growth factor, augmenter of liver regeneration 0.487027
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.475634
ACHE acetylcholinesterase (Yt blood group) 0.465038
CLTC clathrin, heavy chain (Hc) 0.454093
NLE1 notchless homolog 1 (Drosophila) 0.44129
NMT1 N-myristoyltransferase 1 0.431519
CD79A CD79a molecule, immunoglobulin-associated alpha 0.416147
TXN thioredoxin 0.394118
AMD1 adenosylmethionine decarboxylase 1 0.351555
EPHA4 EPH receptor A4 0.314278
SUMF2 sulfatase modifying factor 2 0.298371
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.260891
WDFY2 WD repeat and FYVE domain containing 2 0.252774
BSG basigin (Ok blood group) 0.185612
LCT lactase 0.169812
TYMP thymidine phosphorylase 0.146294
NTS neurotensin 0.145765
NKX2-1 NK2 homeobox 1 0.139739
ADCY2 adenylate cyclase 2 (brain) 0.137037
LCK LCK proto-oncogene, Src family tyrosine kinase 0.136749
AVP arginine vasopressin 0.135253
F2 coagulation factor II (thrombin) 0.130957
PARP1 poly (ADP-ribose) polymerase 1 0.12894