bradykinin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation. (Chemical Entities of Biological Interest Ontology, CHEBI_3165)
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Genes

39 genes co-occuring with the biological term bradykinin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AGTR1 angiotensin II receptor, type 1
ATF1 activating transcription factor 1
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CPB2 carboxypeptidase B2 (plasma)
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
EPHX2 epoxide hydrolase 2, cytoplasmic
F12 coagulation factor XII (Hageman factor)
HCRTR1 hypocretin (orexin) receptor 1
IL6 interleukin 6
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KNG1 kininogen 1
LMNA lamin A/C
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PLAT plasminogen activator, tissue
PON1 paraoxonase 1
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RAB11A RAB11A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RHOA ras homolog family member A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
VEGFA vascular endothelial growth factor A