brain neoplasms; glioma Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cancer (Genetic Association Database)
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Genes

66 genes associated with the disease brain neoplasms; glioma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATM ATM serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTBD2 BTB (POZ) domain containing 2
CCDC26 CCDC26 long non-coding RNA
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHAF1A chromatin assembly factor 1, subunit A (p150)
DCLRE1C DNA cross-link repair 1C
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EME1 essential meiotic structure-specific endonuclease 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
GEN1 GEN1 Holliday junction 5' flap endonuclease
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HMGA2 high mobility group AT-hook 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL12B interleukin 12B
IL27 interleukin 27
IL4 interleukin 4
IL6 interleukin 6
KDR kinase insert domain receptor
LIG1 ligase I, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3
MGMT O-6-methylguanine-DNA methyltransferase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUS81 MUS81 structure-specific endonuclease subunit
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NQO1 NAD(P)H dehydrogenase, quinone 1
PARP1 poly (ADP-ribose) polymerase 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
POMT1 protein-O-mannosyltransferase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAD52 RAD52 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
SHFM1 split hand/foot malformation (ectrodactyly) type 1
TERT telomerase reverse transcriptase
TP53 tumor protein p53
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6