brain Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description 1: The portion of the vertebrate central nervous system that constitutes the organ of thought and neural coordination, includes all the higher nervous centers receiving stimuli from the sense organs and interpreting and correlating them to formulate the motor impulses, is made up of neurons and supporting and nutritive structures, is enclosed within the skull, and is continuous with the spinal cord through the foramen magnum. Also named encephalon. 2: A nervous center in invertebrates comparable in position and function to the vertebrate brain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000142)
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Genes

33 genes associated with the disease brain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
BOK BCL2-related ovarian killer
CADPS2 Ca++-dependent secretion activator 2
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CNTN5 contactin 5
CSMD2 CUB and Sushi multiple domains 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DENND4A DENN/MADD domain containing 4A
DNAH11 dynein, axonemal, heavy chain 11
ELMO1 engulfment and cell motility 1
EMC1 ER membrane protein complex subunit 1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FGF14 fibroblast growth factor 14
FRMD6 FERM domain containing 6
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLYATL3 glycine-N-acyltransferase-like 3
HMGA2 high mobility group AT-hook 2
KANSL1 KAT8 regulatory NSL complex subunit 1
KCNIP4 Kv channel interacting protein 4
NTN4 netrin 4
PTPRD protein tyrosine phosphatase, receptor type, D
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
SBNO1 strawberry notch homolog 1 (Drosophila)
SGCZ sarcoglycan, zeta
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SHB Src homology 2 domain containing adaptor protein B
SLIT1 slit homolog 1 (Drosophila)
SNTG1 syntrophin, gamma 1
ST5 suppression of tumorigenicity 5
THSD7B thrombospondin, type I, domain containing 7B
TNNI3K TNNI3 interacting kinase
ULK4 unc-51 like kinase 4
WDR70 WD repeat domain 70
YAP1 Yes-associated protein 1