| Dataset | GO Cellular Component Annotations 2015 |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. (Gene Ontology, GO_0070531) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0070531 |
| Similar Terms | |
| Downloads & Tools |
7 proteins localized to the brca1-a complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.
| Symbol | Name |
|---|---|
| BABAM1 | BRISC and BRCA1 A complex member 1 |
| BARD1 | BRCA1 associated RING domain 1 |
| BRCA1 | breast cancer 1, early onset |
| BRCC3 | BRCA1/BRCA2-containing complex, subunit 3 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| FAM175A | family with sequence similarity 175, member A |
| UIMC1 | ubiquitin interaction motif containing 1 |
