brd4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description bromodomain containing 4|The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23476)
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Genes

29 genes co-occuring with the biological term brd4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AURKB aurora kinase B
BRD2 bromodomain containing 2
BRD3 bromodomain containing 3
BRD4 bromodomain containing 4
CCHCR1 coiled-coil alpha-helical rod protein 1
CCNT1 cyclin T1
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CSNK2A1 casein kinase 2, alpha 1 polypeptide
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HMOX1 heme oxygenase 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
JMJD6 jumonji domain containing 6
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO1 NAD(P)H dehydrogenase, quinone 1
NUTM1 NUT midline carcinoma, family member 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RN7SK RNA, 7SK small nuclear
RRP1B ribosomal RNA processing 1B
SIPA1 signal-induced proliferation-associated 1
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TP53 tumor protein p53
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1