| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the brinzolamide-1615 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT11 | acyl-CoA thioesterase 11 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| ATR | ATR serine/threonine kinase |
| BAX | BCL2-associated X protein |
| BRAP | BRCA1 associated protein |
| C11ORF58 | chromosome 11 open reading frame 58 |
| CAPRIN1 | cell cycle associated protein 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCND2 | cyclin D2 |
| CD164 | CD164 molecule, sialomucin |
| CD300A | CD300a molecule |
| CDC5L | cell division cycle 5-like |
| CDK8 | cyclin-dependent kinase 8 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CRY1 | cryptochrome circadian clock 1 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTBP2 | C-terminal binding protein 2 |
| CXORF56 | chromosome X open reading frame 56 |
| DAXX | death-domain associated protein |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DERL1 | derlin 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DST | dystonin |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FASTK | Fas-activated serine/threonine kinase |
| FNBP1 | formin binding protein 1 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| FYB | FYN binding protein |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOLM1 | golgi membrane protein 1 |
| GTPBP4 | GTP binding protein 4 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIRA | histone cell cycle regulator |
| HIST1H2BD | histone cluster 1, H2bd |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSF2 | heat shock transcription factor 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| INSIG1 | insulin induced gene 1 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LMAN1 | lectin, mannose-binding, 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| METAP2 | methionyl aminopeptidase 2 |
| METTL8 | methyltransferase like 8 |
| MFN1 | mitofusin 1 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MTMR2 | myotubularin related protein 2 |
| NDRG2 | NDRG family member 2 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NMD3 | NMD3 ribosome export adaptor |
| NRBP1 | nuclear receptor binding protein 1 |
| PDCL | phosducin-like |
| PDZD8 | PDZ domain containing 8 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PFDN1 | prefoldin subunit 1 |
| PHF8 | PHD finger protein 8 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRRC1 | proline-rich coiled-coil 1 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
| RAD17 | RAD17 homolog (S. pombe) |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RDX | radixin |
| RGS1 | regulator of G-protein signaling 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRT1 | sirtuin 1 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B |
| SOAT1 | sterol O-acyltransferase 1 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SQLE | squalene epoxidase |
| SRI | sorcin |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| THADA | thyroid adenoma associated |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMOD1 | tropomodulin 1 |
| TOX4 | TOX high mobility group box family member 4 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UNC119B | unc-119 homolog B (C. elegans) |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| ZFR | zinc finger RNA binding protein |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| ACOT8 | acyl-CoA thioesterase 8 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BIN2 | bridging integrator 2 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CALHM2 | calcium homeostasis modulator 2 |
| CARD9 | caspase recruitment domain family, member 9 |
| CASZ1 | castor zinc finger 1 |
| CD33 | CD33 molecule |
| CD69 | CD69 molecule |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CPNE1 | copine I |
| CPOX | coproporphyrinogen oxidase |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEXI | Dexi homolog (mouse) |
| DNM1 | dynamin 1 |
| EGR2 | early growth response 2 |
| EXOSC10 | exosome component 10 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| GALE | UDP-galactose-4-epimerase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GOLGA3 | golgin A3 |
| GPATCH2 | G patch domain containing 2 |
| GYS1 | glycogen synthase 1 (muscle) |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF7 | interferon regulatory factor 7 |
| KIF1BP | KIF1 binding protein |
| KIF3B | kinesin family member 3B |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LMBRD1 | LMBR1 domain containing 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC59 | leucine rich repeat containing 59 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MARCKSL1 | MARCKS-like 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRR3 | proline rich 3 |
| PSKH1 | protein serine kinase H1 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB5B | RAB5B, member RAS oncogene family |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SDC4 | syndecan 4 |
| SEC13 | SEC13 homolog (S. cerevisiae) |
| SEC24C | SEC24 family member C |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH2D3C | SH2 domain containing 3C |
| SIRT6 | sirtuin 6 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STX18 | syntaxin 18 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| THAP7 | THAP domain containing 7 |
| TJP2 | tight junction protein 2 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TUBA1A | tubulin, alpha 1a |
| VASP | vasodilator-stimulated phosphoprotein |
| VGLL4 | vestigial-like family member 4 |
| XAF1 | XIAP associated factor 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZDHHC4 | zinc finger, DHHC-type containing 4 |
| ZNF189 | zinc finger protein 189 |
| ZNF629 | zinc finger protein 629 |
