| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the brinzolamide-3230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA4 | carbonic anhydrase IV |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CD8B | CD8b molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CLEC2B | C-type lectin domain family 2, member B |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCN | decorin |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EFNB3 | ephrin-B3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR4 | early growth response 4 |
| EXPH5 | exophilin 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GYG2 | glycogenin 2 |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HHAT | hedgehog acyltransferase |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IFT54 | intraflagellar transport 54 |
| IL22 | interleukin 22 |
| IQCG | IQ motif containing G |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF1C | kinesin family member 1C |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK4 | mitogen-activated protein kinase 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MCAM | melanoma cell adhesion molecule |
| MTA1 | metastasis associated 1 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NF1 | neurofibromin 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY2R | neuropeptide Y receptor Y2 |
| NTM | neurotrimin |
| PARVA | parvin, alpha |
| PLCE1 | phospholipase C, epsilon 1 |
| POLM | polymerase (DNA directed), mu |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PROL1 | proline rich, lacrimal 1 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB3B | RAB3B, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHAG | Rh-associated glycoprotein |
| RUNDC3B | RUN domain containing 3B |
| S100A9 | S100 calcium binding protein A9 |
| SC5D | sterol-C5-desaturase |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SLC16A4 | solute carrier family 16, member 4 |
| SMAD4 | SMAD family member 4 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TPM2 | tropomyosin 2 (beta) |
| TRIM3 | tripartite motif containing 3 |
| TRO | trophinin |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| USP46 | ubiquitin specific peptidase 46 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| YOD1 | YOD1 deubiquitinase |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CDON | cell adhesion associated, oncogene regulated |
| CEP85 | centrosomal protein 85kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CFAP69 | cilia and flagella associated protein 69 |
| CIC | capicua transcriptional repressor |
| CLSPN | claspin |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRLF1 | cytokine receptor-like factor 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMID1 | EMI domain containing 1 |
| FAM131A | family with sequence similarity 131, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAN | gigaxonin |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| H1F0 | H1 histone family, member 0 |
| HIST1H2AL | histone cluster 1, H2al |
| HOXD11 | homeobox D11 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI35 | interferon-induced protein 35 |
| IL15RA | interleukin 15 receptor, alpha |
| INO80D | INO80 complex subunit D |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDHB | lactate dehydrogenase B |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYZ | lysozyme |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MSI1 | musashi RNA-binding protein 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTSS1L | metastasis suppressor 1-like |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| NBEAL2 | neurobeachin-like 2 |
| NLGN1 | neuroligin 1 |
| NLRX1 | NLR family member X1 |
| NRSN2 | neurensin 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| POMT2 | protein-O-mannosyltransferase 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD51B | RAD51 paralog B |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| REEP1 | receptor accessory protein 1 |
| RGS20 | regulator of G-protein signaling 20 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TIGD6 | tigger transposable element derived 6 |
| TOM1 | target of myb1 (chicken) |
| TSPYL2 | TSPY-like 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBTD1 | ubiquitin domain containing 1 |
| VASH2 | vasohibin 2 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF442 | zinc finger protein 442 |
