| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the brinzolamide-5016 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALS2CL | ALS2 C-terminal like |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| AVPR1A | arginine vasopressin receptor 1A |
| BAX | BCL2-associated X protein |
| BMP4 | bone morphogenetic protein 4 |
| BMP5 | bone morphogenetic protein 5 |
| CAPN9 | calpain 9 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNO | cyclin O |
| CDH8 | cadherin 8, type 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DMPK | dystrophia myotonica-protein kinase |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK5 | docking protein 5 |
| EPHB6 | EPH receptor B6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXPH5 | exophilin 5 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FSCN1 | fascin actin-bundling protein 1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GK | glycerol kinase |
| GM2A | GM2 ganglioside activator |
| GPR22 | G protein-coupled receptor 22 |
| H2AFX | H2A histone family, member X |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HIC2 | hypermethylated in cancer 2 |
| HIRA | histone cell cycle regulator |
| HN1L | hematological and neurological expressed 1-like |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL1B | interleukin 1, beta |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL6ST | interleukin 6 signal transducer |
| IRF9 | interferon regulatory factor 9 |
| IRS2 | insulin receptor substrate 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISL1 | ISL LIM homeobox 1 |
| ITGB8 | integrin, beta 8 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KHSRP | KH-type splicing regulatory protein |
| KIFC1 | kinesin family member C1 |
| KLHL22 | kelch-like family member 22 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC644450 | uncharacterized LOC644450 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MARS | methionyl-tRNA synthetase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED1 | mediator complex subunit 1 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MFAP2 | microfibrillar-associated protein 2 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RRBP1 | ribosome binding protein 1 |
| S100A8 | S100 calcium binding protein A8 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SH2D2A | SH2 domain containing 2A |
| SLC16A4 | solute carrier family 16, member 4 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| STRA6 | stimulated by retinoic acid 6 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TLR5 | toll-like receptor 5 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM45A | transmembrane protein 45A |
| TMEM63A | transmembrane protein 63A |
| TRD | T cell receptor delta locus |
| TUBA3C | tubulin, alpha 3c |
| VASH2 | vasohibin 2 |
| VIM | vimentin |
| ZNF230 | zinc finger protein 230 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ARRB1 | arrestin, beta 1 |
| ATF3 | activating transcription factor 3 |
| AXIN1 | axin 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B9D2 | B9 protein domain 2 |
| BLNK | B-cell linker |
| BMP15 | bone morphogenetic protein 15 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DMTN | dematin actin binding protein |
| DOC2A | double C2-like domains, alpha |
| EFNA3 | ephrin-A3 |
| EPPK1 | epiplakin 1 |
| FAM120C | family with sequence similarity 120C |
| FAM186A | family with sequence similarity 186, member A |
| FAM63A | family with sequence similarity 63, member A |
| FGL1 | fibrinogen-like 1 |
| FRMD1 | FERM domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HDAC5 | histone deacetylase 5 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0754 | KIAA0754 |
| KIZ | kizuna centrosomal protein |
| KLHL36 | kelch-like family member 36 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAMA3 | laminin, alpha 3 |
| LHX6 | LIM homeobox 6 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP2 | matrix metallopeptidase 2 |
| MYOZ3 | myozenin 3 |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ONECUT2 | one cut homeobox 2 |
| PDE8B | phosphodiesterase 8B |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G3 | phospholipase A2, group III |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCPEP1 | serine carboxypeptidase 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLN | sarcolipin |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCP10 | t-complex 10 |
| TCTN2 | tectonic family member 2 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPYL2 | TSPY-like 2 |
| XAB2 | XPA binding protein 2 |
| XDH | xanthine dehydrogenase |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF442 | zinc finger protein 442 |
| ZNF574 | zinc finger protein 574 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
